In vitro Investigation of Antimicrobial and Antioxidant Properties of Green Silver Nanoparticles Synthesized Using Ephedra gerardiana Plant Extract.

Background: The increasing prevalence of antibiotic-resistant bacteria necessitates exploring nanotechnology as a potential solution for microbial elimination.

Objectives: This study aimed to investigate the antimicrobial and antioxidant effects of silver nanoparticles synthesized using aqueous extract from the Ephedra gerardiana (E. gerardiana) plant (EG@AgNPs).

Development and validation of the Iranian Minimum Data Set for Epidermolysis Bullosa: A mixed method approach.

Minimum Data Set (MDS) enables integration in data collection, uniform data reporting, and data exchange across clinical and research information systems. The current study was conducted to determine a comprehensive national MDS for the Epidermolysis Bullosa (EB) information management system in Iran. This cross-sectional descriptive study consists of three steps: systematic review, focus group discussion, and the Delphi technique.

The mediating role of physical activity, morning wake-up time, and sleep-inducing medication use in the relationship between age and depression: a path analysis of a large kurdish cohort study in Iran.

Background: Depression is a common and debilitating psychiatric disorder worldwide. Recognizing the relationships between depression-related factors can play a significant role in depression management. However, no study has yet used path analysis to examine the mediating role of physical activity, morning wake-up time, and sleep-inducing medication in the relationship between age and depression.

Efficacy of umbilical cord-derived mesenchymal stem cells and exosomes in conjunction with standard IBD drug on immune responses in an IBD mouse model.

Background: Inflammatory bowel disease (IBD) is a persistent inflammation of the digestive system, and Mesenchymal Stem Cells (MSCs) and their exosomes have demonstrated potential as treatments for this condition. The objective of this research was to examine the possible effectiveness of intraperitoneal injection of umbilical cord-MSCs (UC-MSCs) and their exosomes through a two-time injection regimen in a mouse model.

Method: In this study, an animal model of a specific type of IBD in C57BL/6 mice, induced by dextran sulfate sodium (DSS), was utilized.

Computational investigation of the global prevalence of multidrug resistant : A systematic review and meta-analysis.

Background: Leprosy is a chronic infectious disease caused by () However, the emergence of drug-resistant strains of this bacterium, especially multidrug-resistant (MDR) strains, is a serious concern. This study aimed to evaluate the global prevalence of MDR and its implications.

Methods: Using PRISMA guidelines, we systematically reviewed ISI Web of Science, MEDLINE, and EMBASE up to August 2023 to assess the prevalence of MDR .

Assessment of Coffee Consumption on Post-Cesarean Section Bowel Movements.

Objectives: Gastrointestinal complications and bowel movement disorders are common complications of abdominal surgery. Considering the effects of coffee and the high prevalence of cesarean section operations, this study aimed to assess how coffee consumption affected the motility of the intestines.

Methods: This was a triple-blind clinical trial study performed on 200 cases of randomly chosen women who had undergone cesarean section in both Akbarabadi and Firouzgar hospitals, and they were randomly divided into two groups.

Cerebrovascular accident and essential and toxic metals: cluster analysis and principal component analysis.

Background: Cerebrovascular accidents are known as a great cause of morbidity and mortality worldwide. Although there are known risk factors for ischemic stroke, the cases that cannot be justified with these risk factors are increasing. Toxic metals as a potential risk factor for other diseases in humans are assessed in this study in the CVA group and compared to controls.

Association between latent toxoplasmosis and bipolar disorder: a case-control seroprevalence study.

Background: Toxoplasma gondii (T. gondii) is the most successful obligate protozoan that can infect warm-blooded vertebrate hosts. Some researchers suggest that the presence of Toxoplasma cysts in the brain can lead to mental disorders.

Anchoring spinel cobalt and zinc ferrites on zeolite for highly synergic photocatalytic reduction of chromium (VI).

To tackle the challenges of increasing the efficiency of photocatalysts, a ternary magnetic heterojunction photocatalyst containing spinel cobalt and zinc ferrites, and zeolite (CZZ) was designed and fabricated. The physicochemical properties of the novel photocatalyst were verified using characterization techniques such as XRD, FT-IR, FE-SEM, EDS mapping, N adsorption-desorption, VSM, PL, and UV-Vis DRS. The CZZ photocatalyst exhibited a significant Cr (VI) reduction rate of 0.

Exploring oral candidiasis among cancer patients undergoing chemotherapy in eastern Iran.

Background And Objectives: Understanding the epidemiology of species among cancer patients is crucial for preventing invasive infections. This study aimed to identify species and assess risk factors among cancer patients receiving chemotherapy in Birjand, eastern Iran.

Materials And Methods: The samples were obtained from the oral cavity of 140 patients and the initial identification of species was carried out through fungal cultures.

The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran.

Background And Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.

Materials And Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. Antifungal susceptibility testing was done by the CLSI M27-A4 document.

The effect of educational intervention through sending emails on improving physical posture in female computer users of Eastern Iran: a quasi-experiment study.

Background: Musculoskeletal disorders are among the most common occupational injuries and disabilities in developing and industrialized countries. This study aims to determine the effectiveness of e-mail training to improve the physical posture of female computer users at Birjand University of Medical Sciences in Iran.

Methods: The present interventional research explores the effect of email-based training to correct the body posture of female computer users in Birjand, Iran.

Protective Effects of Some Graded Iranian Honey Samples Against Cold Water Immersion-Induced Gastric Ulcers in Rats.

Honey has a rich history of treating gastrointestinal diseases due to its diverse bioactive compounds. This study evaluated the protective effects of select Iranian honeys against cold water immersion stress (CWIS)-induced ulcers in rats. Forty male Wistar rats (250-280 g) were randomly assigned to eight groups ( = 5): control, CWIS, and groups treated with strong (eucalyptus, Annaab, and Jangale) and weak honeys (Chand Giah, Sumaq, Gaz) + CWIS.

Saline nebulizers in treatment of bronchiolitis.

Introduction: This study was conducted to assess the response to treatment and compare the effects of nebulized normal saline 0.9% and hypertonic saline 3% in the management of acute bronchiolitis, a condition associated with multiple complications in pediatric patients.

Materials And Methods: In this clinical trial, a total of 60 children diagnosed with viral bronchiolitis in the autumn and winter of 2018 at Ali Asghar Children's Hospital's emergency department were enrolled.

Corrigendum: The impact of non-coding RNAs in the epithelial to mesenchymal transition.

[This corrects the article DOI: 10.3389/fmolb.2021.

Investigating the resilience of kidneys in rats exposed to chronic partial sleep deprivation and circadian rhythm disruption as disruptive interventions.

Sleep is a vital biological function that significantly influences overall health. While sleep deprivation (SD) and circadian rhythm disruption are known to negatively impact various organs, their specific effects on kidney function remain understudied. This study aimed to investigate the impact of chronic partial sleep deprivation and circadian rhythm disruption on renal function in rats, providing insights into the relationship between sleep disturbances and kidney health.

Molecular identification and subtypes analysis of Blastocystis in South Khorasan province, Eastern Iran.

Background: Blastocystis is a prevalent intestinal parasitic protist that infects both birds and animals. There are at least 44 subtypes (ST) of Blastocystis, with ST1-ST9 being found in humans. The correlation between specific subtypes and pathogenicity has not been definitively established.

Sex differences in hypertension incidence and risk factors: a population-based cohort study in Southern Iran.

Background: Hypertension (HTN) is a major global public health concern. This study aims to identify gender differences to inform more effective prevention strategies and targeted management approaches.

Methods: This prospective cohort study included 7,710 participants aged 40 to 70 years, with a mean follow-up duration of 5.

An Survey on the Effect of Six Commercial Brands of Phosphoric Acid on the Micro-shear Bond Strength of Composite Resin to Enamel.

Statement Of The Problem: One of the most important factors in the clinical longevity of composite resin restorations is proper adhesion, which is achieved using phosphoric acid. Different phosphoric acid products might affect the micro-shear bond strength of composite resin to enamel.

Purpose: The present study aimed to evaluate the micro-shear bond strength of composite resin to sound enamel using six different brands of acid-etch agents.

The evaluation of depression prevalence and its association with obesity phenotypes in a community-dwelling aged population.

Background: Depression is one of the most debilitating mental disorders and a risk factor for many other chronic diseases that are commonly seen in the geriatric population. It has been claimed in previous studies that depression can be associated with obesity in this age group, but there is no common consensus between their results.

Aim: This study aims to evaluate the association between depression metabolic syndrome and obesity phenotypes in community-dwelling older adults living in the East of Iran.

Stimuli-responsive carrageenan-based biomaterials for biomedical applications.

Carrageenan-based biomaterials have attracted considerable attention in recent years due to their unique biological properties, including their biodegradability, compatibility, and lack of adverse effects. These biomaterials exhibit a variety of beneficial properties, such as antiviral, antitumor, and immunomodulatory effects, which set them apart from other polysaccharides. Stimuli-responsive carrageenan-based biomaterials have attracted particular attention due to their unique properties, such as reducing systemic toxicity and controlling drug release.

Association of HPA Antigens with Immune Thrombocytopenia: A Case-Control Study by PCR-SSP Method.

Human platelet antigens (HPAs) play a clinically significant role in alloimmunization and the development of immune-mediated disorders such as immune thrombocytopenia (ITP), fetal and neonatal alloimmune thrombocytopenia (FNAIT), and post-transfusion purpura (PTP). Understanding the genetic profiles of HPAs is critical for preventing and treating these conditions. Given the limitations of serological methods in determining HPA genotypes, this study aims to investigate the association between the genotypes of HPA1, HPA2, HPA3, HPA4, and HPA15 antigens and autoimmune thrombocytopenia in Lorestan Province, utilizing the PCR-SSP method.

Computer case-based reasoning simulation versus traditional lectures for medical interns teaching of diagnosis and antibiotic prescribing for acute respiratory infection: a comparative quasi-experimental study.

Background: Acute respiratory infections are a common presentation in clinical practice and medical interns must learn proper diagnosis and antibiotic prescribing. Traditional lecture-based teaching may not provide sufficient opportunities for students to apply their knowledge in realistic scenarios, whereas computer case-based simulations offer an alternative approach that allows active learning and decision-making in simulated patient cases. This study investigated the effectiveness of computer case-based reasoning simulation versus traditional lectures for medical interns teaching of diagnosis and antibiotic prescribing for acute respiratory infections.