Safety assessment of HEA-enriched mycelia on the central nervous system (CNS), cardiovascular system, and respiratory system in ICR male mice.

, an entomopathogenic fungus, is a source of traditional Chinese medicine in China. Due to the low yield of wild , artificial cultivation approaches will be needed to meet the increasing market demand. Using bioreactor culture can increase mass production and the abundance of the active component, N6-(2-hydroxyethyl)-adenosine (HEA).