9 results match your criteria: "Biostatistics Center of Kaohsiung Chang Gung Memorial Hospital[Affiliation]"
Background: We aimed to develop a preoperative model to predict overall survival (OS) in patients with hepatoma undergoing liver resection (LR).
Methods: Patients who underwent LR for Barcelona Clinic Liver Cancer (BCLC) stage 0, A, or B hepatoma were enrolled. Tumor burden score (TBS) scores were determined using the following equation: TBS (Pinna et al.
Background: Whether the etiology of chronic liver disease (CLD) impacts the overall survival (OS) of patients with hepatocellular carcinoma (HCC) remains unclear. We aim to clarify this issue.
Materials And Methods: Between 2011 and 2020, 3941 patients who were newly diagnosed with HCC at our institution were enrolled in this study.
Article Synopsis
- Tumor necrosis is identified as a critical factor influencing the early recurrence of hepatocellular carcinoma (HCC) after liver resection, prompting the development of a predictive model.
- The study included HCC patients who underwent liver resection between 2010 and 2018 and used a multivariate logistic regression model, analyzing six key pathological features to assess recurrence risk.
- The resulting nomogram demonstrated good predictive accuracy (concordance index of 0.722) and effectively matched predictions with observed early recurrences, indicating its utility in clinical settings.
Background: Studies have rarely reported on preoperative predictors of prognosis of patients undergoing liver resection (LR) for HCC ≥10 cm. We developed a simple model to predict overall survival (OS) of these patients.
Methods: We enrolled 305 patients with HCC ≥10 cm undergoing LR.
Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area.
Viruses
March 2023
Department of Hepatology and Gastroenterology, Division of Internal Medicine, Chang Gung Memorial Hospital, Yunlin 638502, Taiwan.
Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment.
View Article and Find Full Text PDFBackground And Aim: The updated Barcelona Clinic Liver Cancer guidelines recommend liver resection (LR) for patients with single hepatocellular carcinoma (HCC) of any size. This study developed a preoperative model for predicting early recurrence in patients undergoing LR for single HCC.
Materials And Methods: We identified 773 patients undergoing LR for single HCC between 2011 and 2017 from the cancer registry database of our institution.
Alpha-Fetoprotein Combined with Radiographic Tumor Burden Score to Predict Overall Survival after Liver Resection in Hepatocellular Carcinoma.
Cancers (Basel)
February 2023
Biostatistics Center of Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, Taiwan.
We evaluated whether combining the radiographic tumor burden score (TBS) and alpha-fetoprotein (AFP) level could be used to stratify overall survival (OS) among hepatocellular carcinoma (HCC) patients after liver resection (LR). Patients who underwent LR for Barcelona Clinic Liver Cancer stage 0, A, or B HCC between 2011 and 2018 were enrolled. TBS scores were calculated using the following equation: TBS = (largest tumor size (in cm)) + (tumor number).
View Article and Find Full Text PDFNon-B, Non-C Hepatocellular Carcinoma in an HBV- and HCV-Endemic Area: A Community-Based Prospective Longitudinal Study.
Viruses
May 2022
College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
A large community cohort of adults who participated in a health screening program from 2003 to 2013 were prospectively analyzed for the risk factors of non-B, non-C (NBNC) hepatocellular carcinoma (HCC). The serostatus of hepatitis B and C of 52,642 participants was linked to the mortality and cancer registration data of the Health and Welfare Data Science Center, Ministry of Health and Welfare, Taiwan. During a median follow-up of 6 years, 35 of the 43,545 participants who were negative for both HBsAg and anti-HCV antibody developed HCC.
View Article and Find Full Text PDFReappraisal of the roles of alpha-fetoprotein in hepatocellular carcinoma surveillance using large-scale nationwide database and hospital-based information.
J Formos Med Assoc
October 2022
Division of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Liver Cancer Clinical Professional Advisory Board of Taiwan Cooperative Oncology Group, Taiwan. Electronic address:
Background/purpose: Controversies over the use of alpha-fetoprotein (AFP) for detection of hepatocellular carcinoma (HCC) existed from guidelines. Using large-scale database and hospital-based information, we aimed to reappraise the role of AFP in HCC surveillance, including proportion of AFP elevation by stage of HCC, additional benefit of AFP in combination of ultrasonography (US) in the detection of early HCC, and survival in early HCC with high AFP levels.
Methods: This retrospective study enrolled 43,437 patients from database of the Taiwan Cancer Registry (TCR) and 4250 patients from Kaohsiung Chang Gung Memorial Hospital (KCGMH) between January 2011 and December 2017.