Phenylboronic Acid-Dopamine Dynamic Covalent Bond Involved Dual-Responsive Polymeric Complex: Construction and Anticancer Investigation.

In cancer treatment, prolonging the retention time of therapeutic agents in tumor tissues is a key point in enhancing the therapeutic efficacy. However, drug delivery by intravenous injection is always subjected to a "CAPIR" cascade, including circulation, accumulation, penetration, internalization, and release. Intratumoral administration has gradually emerged as an ideal alternative approach for nanomedicine because of its independence of blood constituents and minimal systemic toxicities.

Recent Advances in Controlled Synthesis of Upconversion Nanoparticles and Semiconductor Heterostructures.

It's of great importance for construction of upconversion nanoparticles (UCNPs)/semiconductor heterostructures activated by near infrared light, which have gained worldwide research interests owing to important applications in photocatalysis, solar cells, nanomedicine, and etc. In this review, we highlight the synthetic strategies developed to fabricate upconversion nanoparticles based heterostructures, such as chemical epitaxial growth method, electrospinning technique, self-assembly method, hydrothermal method, and etc. Numerous examples are given concerning the use of the strategies to fabricate various microstructures/nanostructures incorporated with UCNPs and semiconductors materials.

Construction of ZnCdS/BiS composite nanospheres with photothermal effect for enhanced photocatalytic activities.

Rational design of photocatalysts with heterostructure is of scientific and technological interest for taking full advantage use of solar energy. Here we demonstrate a facile method to fabricate ZnCdS/BiS composite nanospheres, in which BiS nanorods grown on the surface of ZnCdS nanospheres. The as-prepared ZnCdS@ZnS core-shell nanospheres play a vital role in formation of the ZnCdS@BiS composite nanospheres.

Positively charged helical chain-modified stimuli-responsive nanoassembly capable of targeted drug delivery and photoacoustic imaging-guided chemo-photothermal synergistic therapy.

In cancer treatment, surface modification by penetrating peptides and size control have been exploited as the two main strategies to tackle the problems of deep tumor penetration and cell internalization for nanocarriers. Polymeric nanocarriers with small size are beneficial for deep tumor penetration; however, they always undergo rapid clearance during body circulation and have low tumor accumulation efficiency. To solve this dilemma, a tumor-targeted size-switchable CPT/IR780@H30-PCL-PPI(L-)/PEI(-COOH/FA) nanoassembly with a "pomegranate" construction was designed in this study.

Magnetically Recyclable FeO@Zn CdS Core-Shell Microspheres for Visible Light-Mediated Photocatalysis.

Magnetically recyclable photocatalyst has drawn considerable research interest because of its importance in practical applications. Herein, we demonstrate a facile hydrothermal process to fabricate magnetic core-shell microspheres of FeO@Zn CdS, successfully using FeO@ZnS core-shell microspheres as sacrificed templates. The as-prepared magnetically recyclable photocatalysts show efficient photochemical reduction of Cr(VI) under irradiation of visible light.