3 results match your criteria: "Biomedical Research Institute of Southern California (BRISC)[Affiliation]"
Post-acute COVID-19 syndrome after reinfection and vaccine breakthrough by the SARS-CoV-2 Gamma variant in Brazil.
Int J Infect Dis
January 2022
Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation (Fiocruz) Avenida Brasil 4365 - Manguinhos, Rio de Janeiro, RJ, 21040-3608, Brazil. Electronic address:
We describe a case of prolonged COVID-19 caused by the SARS-CoV-2 Gamma variant in a fully vaccinated healthcare worker, 387 days after an infection caused by lineage B.1.1.
View Article and Find Full Text PDFThe Potential for Immunospecific Therapy in Multiple Sclerosis Based on Identification of Driver Clones of the Disease.
Crit Rev Immunol
June 2021
University of California, San Diego, UCSD Extension, La Jolla, CA 92093-0176.
The autoimmune disease multiple sclerosis (MS) is driven by T cells that are reactive to self-antigens of the brain and spinal cord. Many drugs have been developed to treat MS, but we believe that immune-specific targeting of pathogenic T cells may be a better approach for treatment. This type of therapy identifies specific components of the self-reactive T-cell repertoire that would undergo similar natural selection criteria as those found in driver genes in cancer genesis.
View Article and Find Full Text PDFZika virus and diagnostics.
Curr Opin Pediatr
February 2017
Biomedical Research Institute of Southern California (BRISC), Oceanside, California, USA.
Purpose Of Review: The purpose of this review is to present what is known about the Zika virus (ZIKV) at the time of writing this review. The viral structure and its phylogeny, as well as the limitations of current available techniques used for diagnosis, are discussed.
Recent Findings: Crystallography and cryo-electron microscopy of the whole ZIKV, or a few of its proteins, are confirming its overall antigenic relatedness to other flaviviruses.