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Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease.

J Biol Chem

December 2024

Biosciences Institute, Newcastle University, Newcastle Upon Tyne, UK; NIHR, Biomedical Research Centre, Newcastle Upon Tyne, UK. Electronic address:

Regulatory T cells (Tregs) are immune regulatory T cells that are vital for controlling inflammation. The role of Tregs in inflammatory diseases namely psoriatic arthritis (PsA) is still poorly understood. The underlying reason being a lack of robust unbiased analysis to test the immune regulatory phenotype of human Tregs.

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