Potential of novel electrospun core-shell structured polyurethane/starch (hyaluronic acid) nanofibers for skin tissue engineering: In vitro and in vivo evaluation.

The biomaterials with excellent biocompatibility and biodegradability ¬can lead to satisfactory wound healing. In this study, core-shell structured PU (polyurethane)/St (Starch) and PU/St (Hyaluronic Acid (HA)) nanofibers were fabricated with coaxial electrospinning technique. The morphology characterization of the core-shell structure of nanofibers was investigated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images.

Incorporation of ZnO nanoparticles into heparinised polyvinyl alcohol/chitosan hydrogels for wound dressing application.

Available wound dressings have some major deficiencies including low water vapor transmission rate (WVTR), low absorption of wound fluids, and not providing a suitable and moist environment for wound healing. The main advantage of hydrogels is giving aid to the creation of a moist and cool environment for wound healing and providing high water vapor permeability along with preventing penetration of microbes into the wound surface. Therefore, hydrogels of heparinized polyvinyl alcohol (PVA)/chitosan (CS)/nano zinc oxide (nZnO) were prepared to be used as wound dressing.

Wound healing properties of PVA/starch/chitosan hydrogel membranes with nano Zinc oxide as antibacterial wound dressing material.

In this work, hydrogel membranes were developed based on poly vinyl alcohol (PVA), starch (St), and chitosan (Cs) hydrogels with nano Zinc oxide (nZnO). PVA/St/Cs/nZnO hydrogel membranes were prepared by freezing-thawing cycles, and the aqueous PVA/St solutions were prepared by dissolving PVA in distilled water. After the dissolution of PVA, starch was mixed, and the mixture was stirred.

Effect of surface charge and hydrophobicity of polyurethanes and silicone rubbers on L929 cells response.

Wettability and zeta potential studies were performed to characterize the hydrophobicity and surface charge of virgin and oxygen plasma irradiated silicone rubbers and polyurethane (polyether and polyesther) samples and evaluate the effect of hydrophobicity and surface charge on fibroblast cells attachment and growth. The surface properties of polyurethanes and silicones and plasma irradiated surfaces were compared by water drop contact angle and zeta potential measurement. Using SEM photomicrographs to study the morphology of virgin and plasma irradiated samples surfaces and light microscopy for study the behavior of cell attachment on these surfaces.

Ultra high molecular weight polyethylene and polydimethylsiloxane blend as acetabular cup material.

An acetabular cup shock absorber implant is formed from a composite of polymer materials. The cup consists of three zones such as the articulating surface of the implant is 100% ultra high molecular weight polyethylene (UHMWPE) (zone 1) and shock absorber of the cup contains of polydimethylsiloxane (PDMS) (zone 3). Zone 2 which is designed for better adhesion between zone 1 and zone 2 consists of a blend of UHMWPE and PDMS is a cushion that from one side adheres to zone 1 and the other side to zone 2.