8 results match your criteria: "Biological Research Centre (CIB)[Affiliation]"

1,3-β-glucans are extracellular polysaccharides synthesized by microorganisms and plants, with therapeutic potential. Among them, the 2-substituted-(1-3)-β-D-glucan, synthesized by some lactic acid bacteria (LAB), has a prebiotic effect on probiotic strains, an immunomodulatory effect on monocyte-derived macrophages, and potentiates the ability of the producer strain to adhere to Caco-2 cells differentiated to enterocytes. In this work, the 2-substituted-(1-3)-β-D-glucan polymers produced by GTF glycoyltransferase in the natural host 2.

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High 2,3-butanediol production from glycerol by Raoultella terrigena CECT 4519.

Bioprocess Biosyst Eng

April 2020

Department of Chemical and Materials Engineering, Faculty of Chemistry, Universidad Complutense de Madrid, 28040, Madrid, Spain.

Bioconversion of biodiesel-derived glycerol into 2,3-butanediol has received recently much attention due to its increasing surplus and its multiple uses in industry as bulk chemical. The influence of initial glycerol concentration on 2,3-butanediol production in batch runs has been studied. A concentration higher than 140 g/L produces an inhibitory effect on the final 2,3-butanediol concentration and its production rate.

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Autophagy is a eukaryotic catabolic pathway essential for growth and development. In plants, it is activated in response to environmental cues or developmental stimuli. However, in contrast to other eukaryotic systems, we know relatively little regarding the molecular players involved in autophagy and the regulation of this complex pathway.

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Roles of Amphipathicity and Hydrophobicity in the Micelle-Driven Structural Switch of a 14-mer Peptide Core from a Choline-Binding Repeat.

Chemistry

April 2018

Instituto de Química Física Rocasolano (IQFR), Consejo Superior de Investigaciones Científicas (CSIC), Serrano 119, 28006, Madrid, Spain.

Article Synopsis
  • Choline-binding repeats (CBRs) are common sequences in the surface proteins of various microorganisms, with a specific focus on a 14-mer sequence from S. pneumoniae's LytA autolysin.
  • Previous research shows that this peptide can switch between a stable β-hairpin form in water and an amphipathic α-helix when detergent micelles are present.
  • The study investigates factors affecting this transition, especially the roles of hydrophobicity and amphipathicity, revealing that strong cross-strand interactions are key for β-hairpin stability and that both properties are equally important for stabilizing the α-helix in micelles.
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Background Information: MAPKs (mitogen-activated protein kinases) are involved in the transduction of different signals in eukaryotes. They regulate different processes, such as differentiation, proliferation and stress response. MAPKs act through the phosphorylation cascade, being the last element that phosphorylates the final effector of the cell response.

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Background: Stressful conditions lead to formation of excessive free radicals, and lipid peroxidation is one of the major outcomes of free radical-mediated injury that directly damages membranes and generates a number of secondary products.

Objectives: To determine the levels of malondialdehyde, an end product of lipid peroxidation, according to demographic and occupational variables in workers of a prehospital emergency service and to analyse the relationship between malondialdehyde levels and burnout.

Material And Methods: One hundred and eleven healthy workers of a prehospital emergency service and eighty aged-matched healthy individuals of both sexes as a control group were surveyed.

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The plant hormone abscisic acid regulates gene expression in response to growth stimuli and abiotic stress. Previous studies have implicated members of the bZIP family of transcription factors as mediators of abscisic acid dependent gene expression through the ABRE cis-element. Here, we identify two new maize bZIP transcription factors, EmBP-2 and ZmBZ-1 related to EmBP-1 and OsBZ-8 families.

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