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Vitamin D concentrations, endothelial progenitor cells, and cardiovascular risk factors.

Panminerva Med

June 2010

Center for the Improvement of Human Functioning International, Inc., Bio-communication Research Institute Division, Wichita, KS 67219, USA.

Our study aimed to establish the association of vitamin D status with the level of circulating endothelial progenitor cells (EPCs) and circulating angiogenic cells (CACs) and to demonstrate the effect of vitamin D on the level of lipoproteins responsible for increased cardiovascular risk and high blood pressure. 41 healthy adults were selected. EPCs were defined as CD34+/KDR+ cells, and CACs were defined as cells that expressed endothelial markers after incubation of mononuclear blood cells with endothelial growth factors during 5 days.

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