Significant correlation between glucose metabolism status and acute radiation enteritis resulting from concurrent chemoradiotherapy in rectal cancer.

Objective: To explore the relationship between glucose metabolism and acute radiation enteritis from chemoradiotherapy for rectal cancer.

Methods: In this retrospective study, the clinical data of 75 rectal cancer patients who received concurrent chemoradiotherapy in Binzhou Second People's Hospital from February 2019 to February 2022 were collected and analyzed. According to the Radiation Therapy Oncology Group (RTOG)/European Organization for Research on Treatment of Cancer (EORTC) radiation response grading criteria, the patients were classified into four groups with different glucose metabolism statuses: NGR (normal glucose regulation) group, IFG (impaired fasting glucose) group, IGT (impaired glucose tolerance) group, and DM (diabetes mellitus) group.