High Expression of Lysophosphatidic Acid Induces Nerve Injury in LSS Patients via AKT Mediated NF-κB p65 Pathway.

Lumbar spinal stenosis (LSS) is a spinal degenerative disease, complicated with nerve injury. Lysophosphatidic acid (LPA), a kind of glycerophospholipid molecule is elevated in the initial stages of neural injury. This research aimed to investigate the patho-mechanism of nerve injury caused by LPA in LSS patients.

miRNA-200b improves hepatic fibrosis induced by CCL by regulating toll-like receptor 4 in mice.

To study the effect of miRNA-200b on hepatic fibrosis induced by CCl in mice. The C59BL/6 mice were randomly divided into three groups (normal control [NC], CCLR model [Model], and CCl  + miRNA-200b [miRNA]). The hepatic fibrosis was induced by CCl injected subcutaneously twice per week in Model and miRNA groups.

Analysis of Factors Influencing the Grading of Condition Severity and Zoning Management in an Emergency Triage System.

Background: To identify and analyze factors that influence the grading and zoning management model of emergency triage as a first step in the improvement of the system.

Methods: Questionnaires were used to extract data from clinical histories of 286 patients who attended the Emergency Department of Binzhou Central Hospital (Binzhou City, Shandong Province, China) from September to November of 2015. Through logistic regression analysis, influencing factors for unreasonable (≥ 2h) emergency department retention times were identified.