Congenital self-healing reticulohistiocytosis: An atypical presentation acquired in a 10-month-old.

Congenital self-healing reticulohistiocytosis of Hashimoto and Pritzker (CSHR) is a rare, benign form of Langerhans Cell Histiocytosis (LCH) that presents at birth and involutes by 6 months of age. We present an atypical case of CSHR with the first onset at 7 months of age, treated with surgical excision.

Sentinel lymph node melanoma metastases: Assessment of tumor burden for clinical prediction of outcome in the first Multicenter Selective Lymphadenectomy Trial (MSLT-I).

Purpose: As clinical management decisions in patients with Stage III melanoma have become more complex, precise pathologic characterization of sentinel lymph node (SLN) metastases has become critical to guide management. The extent of SLN involvement correlates with risk of adverse outcomes, but reported methods of disease quantification vary. We examined SLN metastases from patients participating in an international clinical trial and compared several methods of tumor burden quantification.

Rare Case Report of Pilomatrical Carcinosarcoma in a Pediatric Patient.

We present a case report of the exceptionally rare pilomatrical carcinosarcoma in an even rarer pediatric age group, a 9-year-old female patient. The tumor showed biphasic pilomatrical carcinoma and malignant sarcomatous transformation. To date, the patient is healing well without signs of recurrence.