Comprehensive phenolic profiling and biological evaluation of L. (Asteraceae).

The present investigation focused on the comprehensive analysis of the phenolic profile of L. (Asteraceae) and the assessment of its diverse biological activities. Utilising LC-MS/MS, the phytochemical composition of the 70% methanol extract of (CG-ME) was thoroughly elucidated, revealing the presence of 30 distinct phytochemical compounds.

Melatonin hormone level in nurses and factors affecting it; Investigation according to shift working pattern.

This study aimed to determine the relationship between melatonin hormone levels, sleep, and factors affecting sleep, psychological resilience, and depression in nurses working with a shift work system. Conducted between February 5-12, 2021, at the Training and Research Hospital in Ağrı province, the descriptive study included 41 night shift nurses and 35 day shift nurses, totaling 76 participants. Blood samples for melatonin analysis were collected and data were gathered using the Sociodemographic Information Form, Epworth Sleepiness Scale, Sleep Disorder Scale Short Form, Brief Psychological Resilience Scale, and Beck Depression Scale Short Form.

Classification of 3D shoe prints using the PointNet architecture: proof of concept investigation of binary classification of nike and adidas outsoles.

Shoe prints are one of the most common types of evidence found at crime scenes, second only to fingerprints. However, studies involving modern approaches such as machine learning and deep learning for the detection and analysis of shoe prints are quite limited in this field. With advancements in technology, positive results have recently emerged for the detection of 2D shoe prints.

The role of blood nitric oxide level in predicting return of spontaneous circulation: a prospective case-control study.

Objective: The aim of this study was to investigate whether there is a difference in serum nitric oxide levels between patients who return spontaneously after cardiopulmonary resuscitation and those who do not. We also examined the potential of using serum nitric oxide levels as a marker to make an accurate decision about patient survival.

Methods: We included 100 consecutive patients who were brought to the emergency clinic due to cardiac arrest.

Sinonasal Anatomic Variations in the Adult Population: CT Examination of 1200 Patients.

Background: The nasal cavity and paranasal sinuses are one of the most frequently anatomically varied regions. Their size and shape vary from person to person, and ethnic origin may have a role in this variety. Recognizing this variations is so important for ear nose throat (ENT) specialists because they predispose to sinonasal pathologies and affect the complication rate and success of endoscopic sinus surgery.

Effectiveness of Apparent Diffusion Coefficient Values in Predicting Pathologic Subtypes and Grade in Non-Small-Cell Lung Cancer.

Background And Objective: The aim of this study is to evaluate the effectiveness of apparent diffusion coefficient (ADC) values in predicting pathologic subtypes and grade in non-small-cell lung cancer (NSCLC).

Materials And Methods: From January 2018 to March 2020, 48 surgically diagnosed NSCLC cases were included in this study. To obtain ADC values, ADC maps were constructed, and a region of interest was put on the tumor.

Measurement of multijet azimuthal correlations and determination of the strong coupling in proton-proton collisions at .

A measurement is presented of a ratio observable that provides a measure of the azimuthal correlations among jets with large transverse momentum . This observable is measured in multijet events over the range of - based on data collected by the CMS experiment in proton-proton collisions at a centre-of-mass energy of 13 , corresponding to an integrated luminosity of 134 . The results are compared with predictions from Monte Carlo parton-shower event generator simulations, as well as with fixed-order perturbative quantum chromodynamics (pQCD) predictions at next-to-leading-order (NLO) accuracy obtained with different parton distribution functions (PDFs) and corrected for nonperturbative and electroweak effects.

Adverse effects of metamizole on heart, lung, liver, kidney, and stomach in rats.

Background: Metamizole is banned in some countries because of its toxicity, although it is widely used in some European countries. In addition, there is limited information on its safety profile, and it is still debated whether it is toxic to the heart, lungs, liver, kidneys, and stomach.

Aims: Our study investigated the effects of metamizole on the heart, lung, liver, kidney, and stomach tissues of rats.

Effect of abemaciclib and curcumin administration on sex hormones, reproductive functions, and oxidative DNA expression in rats.

This study investigated whether abemaciclib (ABE) administration had any adverse effects on ovarian and sex hormones in female rats, and the protective effect of curcumin. Forty female rats were equally divided into the sham control, DMSO, curcumin (CMN), ABE, and ABE+CMN groups. Pharmaceuticals were administered by gavage daily for 28 days.

Turkish Adaptation of Social Media Questionnaire for Nursing Training.

The use of social media in education has many effects such as rapid dissemination of information, crowdsourced information sharing, learning, and social interaction. In the study, it was aimed to determine the validity and reliability of the Social Media Questionnaire for Nursing Training (SMQNT), which can be used to determine the effect of social media in nursing education. The data of this methodological study were obtained from 262 nursing students.

Evaluation of Femoral Head Avascular Necrosis With Virtual Noncalcium Dual-Energy Computed Tomography.

Objective: Our aim was to investigate the effectiveness of the dual-energy computed tomography (DECT) virtual noncalcium (VNCa) technique in avascular necrosis (AVN) for detecting bone marrow edema (BME) and staging.

Methods: This prospective study included adult patients diagnosed with unilateral or bilateral femoral head AVN between January 2023 and December 2023, who had magnetic resonance imaging (MRI) and DECT. Two participants were excluded from the study due to undergoing surgical procedures during the period between the scans.

Fine-tuning inflow prediction models: integrating optimization algorithms and TRMM data for enhanced accuracy.

This research explores machine learning algorithms for reservoir inflow prediction, including long short-term memory (LSTM), random forest (RF), and metaheuristic-optimized models. The impact of feature engineering techniques such as discrete wavelet transform (DWT) and XGBoost feature selection is investigated. LSTM shows promise, with LSTM-XGBoost exhibiting strong generalization from 179.

The study of the number and localization of the nutrient foramen on the clavicle and its relationship with other clavicle parameters.

Background: Nutrient foramen (NF) is a hole on the long bones that allows the passage of the nutrient artery. The vasculature of the bone is very important for fracture healing and vascularized bone grafting. Therefore, information about the location and number of NFs is important for surgical and clinical practice.

Comparative in silico and in vitro evaluation of possible toxic effects of bisphenol derivatives in HepG2 cells.

Introduction: Bisphenols are widely used in the production of polycarbonate plastics and resin coatings. Bisphenol A (BPA) is suggested to cause a wide range of unwanted effects and "low dose toxicity". With the search for alternative substances to BPA, the use of other bisphenol derivatives namely bisphenol F (BPF) and bisphenol S (BPS) has increased.

Advancements in reusable SERS substrates for trace analysis applications.

Surface Enhanced Raman Spectroscopy (SERS) technique is an effective analytical technique in which fingerprint information about analytes can be obtained, can provide detection limit performance at the single molecule level, and analyzes are performed in a single step without any intermediate steps. SERS technique offers additional benefits rather than other analytical techniques including high selectivity, ultrasensitive detection, uncomplicated protocols, in situ sampling, on-set capability and cost-effectiveness. As a result of the combination of developments in materials and nanotechnology science with the SERS analysis technique, this technique strengthens its use advantage day by day.

Understanding the side effects of chronic silodosin administration via untargeted metabolomics approach.

Background: Precision medicine, which looks for high efficacy and low toxicity in therapies, has increased in popularity with omics technology. This work aims to discover novel and low-toxicity therapy options by examining the complex relationship between silodosin-induced side effects and the metabolomic profiles associated with its administration.

Materials And Methods: The plasma samples of the control group and silodosin-treated rats were analyzed by LC-Q-TOF-MS/MS.

Gingerol containing polymeric nanofibers: a healing touch for accelerated wound recovery.

Objective: In the current research, 6-gingerol (GA)-loaded were developed, and their potential usage in wound healing was evaluated.

Significance: This study investigates the effectiveness of nanofibrous membranes composed of sodium alginate (SA), poly(vinyl alcohol) (PVA), and 6-gingerol (GA) as delivery systems for anti-inflammatory agents in the context of wound dressings.

Methods: GA-loaded SA/PVA nanofiber was prepared using electrospinning.

Constraints on anomalous Higgs boson couplings from its production and decay using the WW channel in proton-proton collisions at .

A study of the anomalous couplings of the Higgs boson to vector bosons, including -violation effects, has been conducted using its production and decay in the WW channel. This analysis is performed on proton-proton collision data collected with the CMS detector at the CERN LHC during 2016-2018 at a center-of-mass energy of 13 TeV, and corresponds to an integrated luminosity of 138 . The different-flavor dilepton final state is analyzed, with dedicated categories targeting gluon fusion, electroweak vector boson fusion, and associated production with a W or Z boson.

Synthesis of new two 1,2-disubstituted benzimidazole compounds: their in vitro anticancer and in silico molecular docking studies.

In this study, two new molecules were synthesized from the reaction of 2-methyl-1H-benzo[d]imidazole with aryl halides in the presence of a strong base. The structures newly of synthesized 1,2-disubstituted benzimidazole compounds were characterized using spectroscopic techniques (FT-IR, HNMR, CNMR) and chromatographic technique (LC/MS). For discovering an effective anticancer drug, the developed heterocyclic compounds were screened against three different human cancer cell lines (A549, DLD-1, and L929).

Docosahexaenoic acid eliminates endoplasmic reticulum stress and inflammatory pathways in diabetic rat keratopathy.

Diabetic keratopathy, characterized by corneal structural changes, is a common complication of diabetes mellitus (DM). Docosahexaenoic acid (DHA), an omega-3 fatty acid, has shown potential therapeutic benefits in various diabetic complications. This study aimed to investigate the protective effect of DHA on corneal tissue in streptozotocin (STZ)-induced type 2 DM in rats.

The relationship between serum uric acid level and carotid intima-media thickness in hemodialysis patients.

Introduction: We aimed to evaluate the relationship between carotid intima-media thickness (CIMT), which is a known indicator of cardiovascular risk and atherosclerosis, and uric acid level, which may be an easy marker for cardiovascular diseases due to its antioxidant and pro-oxidant properties in hemodialysis patients.

Methods: In this cross-sectional study, we evaluated 77 hemodialysis patients. The mean CIMT of these patients was measured and recorded by Doppler ultrasonography.