5,884 results match your criteria: "Bielefeld University.[Affiliation]"

Article Synopsis
  • The study investigated whether e-learning could effectively supplement face-to-face CPR training for schoolchildren in Germany, focusing on measuring CPR knowledge and self-efficacy.
  • A total of 342 students participated, with one group receiving traditional instructor-led CPR training and the other completing a shorter e-learning module before hands-on practice.
  • Results showed that both groups improved their CPR knowledge and self-efficacy, but there was no significant difference in effectiveness between the e-learning and traditional methods.
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Social interactions influence disease spread, information flow and resource allocation across species, yet heterogeneity in social interaction frequency and its fitness consequences are still poorly understood. Additionally, the role of exogenous chemicals, such as non-nutritive plant metabolites that are utilised by several animal species, in shaping social networks remains unclear. Here, we investigated how non-nutritive plant metabolites impact social interactions and the lifespan of the turnip sawfly, Athalia rosae.

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Chromatographic fractionation of CHCl:MeOH (1:1) extract of Schott cultivated in Egypt afforded four compounds, lupeol acetate (), -13--manoyl oxide (), 5-methoxymethyl-7,8-dimethyltocol (), and -tocopherol quinone (). The planar structures of the isolated compounds were concluded based on HRESIMS and NMR spectroscopy. X-ray crystallography of is reported herein for the first time and its unambiguous absolute configuration was deduced from anomalous dispersion.

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Chromosome-level genome assembly of Tritrichomonas foetus, the causative agent of Bovine Trichomonosis.

Sci Data

September 2024

Friedrich-Loeffler-Institut, Institut für Bakterielle Infektionen und Zoonosen (IBIZ), Naumburger Str. 96a, 07743, Jena, Germany.

Tritrichomonas foetus is a parasitic protist responsible for bovine trichomonosis, a reproductive disease associated with significant economic burden to the livestock industry throughout the world. Here, we present a chromosome-level reference genome of T. foetus -KV-1 (ATCC 30924) using short-read (Illumina Miseq), long-read (Oxford Nanopore) and chromatin-linked (Hi-C) sequencing.

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Child maltreatment in a high adversity context: Associations of age, type and timing of exposure with psychopathology in middle childhood.

Child Abuse Negl

November 2024

Department of Human Sciences, Institute of Psychology, Universität der Bundeswehr München, Germany; Non-Governmental Organization Vivo International e.V., Konstanz, Germany.

Background: While cumulative childhood maltreatment (CM) has been linked to psychopathological outcomes, recent studies point to the relevance of the type and timing of exposure. The aim of the current study was to better understand their importance beyond the cumulative burden of CM for psychopathological symptoms in middle childhood.

Methods: A total of N = 341 children (M = 9.

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Introduction: Phages are viruses that infect prokaryotes and can shape microbial communities by lysis, thus offering applications in various fields. However, challenges exist in sampling, isolation and accurate prediction of the host specificity of phages as well as in the identification of newly replicated virions in response to environmental challenges.

Methods: A new workflow using biorthogonal non-canonical amino acid tagging (BONCAT) and click chemistry (CC) allowed the combined analysis of phages and their hosts, the identification of newly replicated virions, and the specific tagging of phages with biotin for affinity chromatography.

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The gender gap in fair earnings increases with age due to higher age premium for men.

Br J Sociol

January 2025

Research Group Gender Economics, German Institute for Economic Research (DIW Berlin), University of Potsdam, Potsdam, Germany.

This study explores how gender and age interact in shaping beliefs about fair pay through a factorial survey experiment conducted with German employees. Respondents evaluated hypothetical worker descriptions varying in age, gender, and earnings. While no gender gap in fair earnings was found for the youngest hypothetical workers, a significant gap favoring men emerged with increasing age.

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Magnetic cooling, a solid-state refrigeration technology based on the magnetocaloric effect, has attracted significant attention in space cooling due to its high energy-efficiency and environmental friendliness. Transition metal-based magnetocaloric materials (MCMs) with the merit of low-cost have emerged as promising candidates for efficient magnetic refrigeration applications. This review explores the intricate relationship between microstructure and multiple properties (e.

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Effects of acute stress on biological motion perception.

PLoS One

September 2024

Neurocognition and Action-Biomechanics Research Group, Faculty of Psychology and Sports Science, Bielefeld University, Bielefeld, Germany.

Biological motion perception is an essential part of the cognitive process. Stress can affect the cognitive process. The present study explored the intrinsic ERP features of the effects of acute psychological stress on biological motion perception.

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, also knowen as the Japanese tea hortensia, is known for its sweet taste and health properties of bevarages produced from this plant. The 3,4-dihydroisocoumarins, hydrangenol and phyllodulcin harbour a variety of biological activities and pharmacological properties. Therefore, a detailed understanding of dihydroisocoumarin biosynthesis in is of major interest.

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A combination of life history traits and environmental conditions has been highlighted as the main drivers of avian breeding success. While drivers of breeding success are well known in some species, especially birds in northern, temperate regions; species in other parts of the world have received relatively little attention. In this study, we used a long-term dataset on breeding success of tropical plovers from south-west Madagascar to investigate whether nest survival changed over time and whether the drivers of nest survival were similar for multiple species breeding in the same arid habitat.

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Background: While the efficacy of digital interventions for the treatment of depression is well established, comprehensive knowledge on how therapeutic changes come about is still limited. This systematic review aimed to provide an overview of research on change mechanisms in digital interventions for depression and meta-analytically evaluate indirect effects of potential mediators.

Methods: The databases CENTRAL, Embase, MEDLINE, and PsycINFO were systematically searched for randomized controlled trials investigating mediators of digital interventions for adults with depression.

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One the development of a professional mandate by social workers in medical rehabilitation- key results from the SWIMMER Project.

Front Rehabil Sci

August 2024

Faculty of Medicine, Institute for Rehabilitation Medicine, Interdisciplinary Centre of Health Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

Social work in the German rehabilitation sector is practiced with great variation and its interventions lack research evidence. The SWIMMER project aims to develop a program theory of social work in rehabilitation to explain this variation and to discuss possible conditions. The dealing with ethical dilemmas by social workers is one possible influence and the focus of this paper.

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Chronic Activation of Tubulin Tyrosination Improves Heart Function.

Circ Res

October 2024

Department of Experimental Pharmacology and Toxicology (N.P., B.G., E.K., G.M., S.S., L.C.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Article Synopsis
  • - Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder linked to sarcomere gene mutations, resulting in left ventricular thickening and diastolic dysfunction; new research emphasizes the importance of microtubule alterations in heart failure.
  • - The study explored the effects of increasing tubulin tyrosination via adeno-associated virus transfer in various models, including HCM human cardiomyocytes and specific mouse models, revealing that this approach improved heart function by reducing harmful microtubule modifications and enhancing contractility.
  • - Results indicated that enhancing tubulin tyrosination led to better heart function metrics such as contractility and cardiac output in both human and mouse models, while also suggesting potential benefits of targeting the micro
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Mammals show faster recovery from capture and tagging in human-disturbed landscapes.

Nat Commun

September 2024

Plant Ecology and Nature Conservation, Institute of Biochemistry and Biology, University of Potsdam, 14469, Potsdam, Germany.

Article Synopsis
  • Wildlife tagging is important for understanding animal behavior and ecology, but the stress from this process can affect their movement and activity levels after being released.
  • An analysis of 1585 individuals from 42 mammal species showed that over 70% exhibited significant behavioral changes post-tagging, with herbivores traveling farther while omnivores and carnivores were less active initially.
  • Recovery from stress was generally quick, typically within 4-7 days, and animals in areas with a high human presence adapted faster, suggesting that tracking durations should be longer and consider species and location when designing studies.
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Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants.

Environ Int

September 2024

Physiology and Pathophysiology of Cells and Membranes, Medical School OWL, Bielefeld University, 33615 Bielefeld, Germany. Electronic address:

Faced with unpredictable changes in global weather patterns, release and redistribution of metals through land erosion and water movements add to the increasing use of metals in industrial activities causing high levels of environmental pollution and concern to the health of all living organisms. Cadmium is released into the environment by smelting and mining, entering the food chain via contaminated soils, water, and phosphate fertilizers. Bioaccumulation of cadmium in plants represents the first major step into the human food chain and contributes to toxicity of several organs, especially the kidneys, where biomagnification of cadmium occurs over decades of exposure.

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Integrating federated learning for improved counterfactual explanations in clinical decision support systems for sepsis therapy.

Artif Intell Med

November 2024

Department of Anaesthesiology, Intensive Care, Emergency Medicine, Transfusion Medicine and Pain Therapy, University Hospital OWL, Campus Bielefeld-Bethel, Protestant Hospital of the Bethel Foundation, Burgsteig 13, Bielefeld, 33617, Germany. Electronic address:

In recent years, we have witnessed both artificial intelligence obtaining remarkable results in clinical decision support systems (CDSSs) and explainable artificial intelligence (XAI) improving the interpretability of these models. In turn, this fosters the adoption by medical personnel and improves trustworthiness of CDSSs. Among others, counterfactual explanations prove to be one such XAI technique particularly suitable for the healthcare domain due to its ease of interpretation, even for less technically proficient staff.

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Background: To recognize the interplay between climate change and public health, this study examines the impact of sports organizations' environmental initiatives on members' subjective well-being (SWB) and climate change attitudes (CCA). Drawing on the theoretical tenets of pro-social behavior, organizational initiatives aiming at protecting and improving the natural environment can be viewed as altruistic. This altruism can in turn increase SWB.

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Article Synopsis
  • Parkinson's disease (PD) negatively impacts health-related quality of life (HRQoL), particularly among Arabic-speaking individuals, highlighting a need for validated measurement scales in this population.
  • A scoping review conducted in December 2022 analyzed existing studies to identify HRQoL measurement scales that are validated for Arabic speakers with PD, focusing on their psychometric properties.
  • The review found that while several HRQoL scales exist for PD, only one has been specifically validated in Arabic, indicating a significant gap in resources for this demographic.
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Validation of the Scale of Emotional Development-Short (SED-S) in Healthy Adults with an Intellectual Disability.

J Clin Med

August 2024

Medical School and University Medical Center OWL, Mara Hospital, University Clinic for People with Neurodevelopmental Disorders, Bielefeld University, 33617 Bielefeld, Germany.

The Scale of Emotional Development-Short (SED-S) assesses the level of emotional development (ED) of persons with intellectual disability (ID) in eight domains across five stages with reference ages from 0 to 12 years. The aim of this study was to apply and validate the SED-S in a sample of healthy adults with ID. Eighty-three mentally healthy adults with ID were assessed using the SED-S.

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Background: Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunctions. Consequently, the disease burden is substantial, and treatment choices are limited. In this randomized, double-blind study, we conducted repeated prefrontal electrical stimulation in 40 patients with MS to evaluate mental health variables (quality of life, sleep difficulties, psychological distress) and cognitive dysfunctions (psychomotor speed, working memory, attention/vigilance), marking it as the third largest sample size tDCS research conducted in MS to date.

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Induction and stabilization of delta frequency brain oscillations by phase-synchronized rTMS and tACS.

Brain Stimul

October 2024

Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany; Bielefeld University, University Hospital OWL, Protestant Hospital of Bethel Foundation, University Clinic of Psychiatry and Psychotherapy, Bielefeld, Germany; German Centre for Mental Health (DZPG), Bochum, Germany. Electronic address:

Background: Brain oscillations in the delta frequency band have been linked with deep sleep and consolidation of declarative memory during sleep. However, the causal relationship of these associations remains not competely clarified, primarily due to constraints by technical limitations of brain stimulation approaches suited to induce and stabilize respective oscillatory activity in the human brain. The objective of this study was to establish a non-invasive brain stimulation protocol capable of reliably inducing, and stabilizing respective oscillatory activity in the delta frequency range.

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Correction for 'Water adsorption lifts the (2 × 1) reconstruction of calcite(104)' by Jonas Heggemann , , 2024, , 21365-21369, https://doi.org/10.1039/D3CP01408H.

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Article Synopsis
  • Blood parasites from a specific genus are common in many bird species, especially raptors like common buzzards.
  • The study examined the relationship between the presence of flowing waters, blackfly vectors, and infection rates in buzzard nestlings.
  • Results showed a high prevalence of infection (56.6% in nestlings) but no strong links to nestling age or distance to streams, indicating complex transmission dynamics influenced by various habitat factors.
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The kidney is the main organ that senses changes in systemic O pressure by hypoxia-PHD-HIFa (HPH) signaling, resulting in adaptive target gene activation, including erythropoietin (EPO). The non-essential transition metal cadmium (Cd) is nephrotoxic and disrupts the renal HPH pathway, which may promote Cd-associated chronic renal disease (CKD). A deeper molecular understanding of Cd interference with renal HPH signaling is missing, and no data with renal cell lines are available.

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