16 results match your criteria: "Bhojani Clinic[Affiliation]"

Dermoscopic and Onychoscopic Features of Dyskeratosis Congenita.

Indian Dermatol Online J

October 2022

Government Hospital for Mental Care, King George Hospital, Visakhapatnam, Andhra Pradesh, India.

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Article Synopsis
  • A novel observation highlights chronic eczema developing on skin lesions of tinea cruris/tinea corporis in six atopic individuals who were adequately treated.
  • It is recommended that skin with dermatophytosis in atopic patients be closely monitored for any secondary changes even after the lesions have healed.
  • The study encourages the use of mild moisturizers and topical antifungal treatments, and suggests further research on the impaired skin barrier in atopic individuals with fungal infections.
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Violence against women and girls (VAWG) is one of the most widespread, persistent and devastating human rights violations in the world today and remains largely unreported due to the impunity, silence, stigma and shame surrounding it even in this era with huge social communication. The incidences of domestic violence, emotional violence, economical violence, sexual assault, rape, molestation, harassment at work place, exploitation, acid attack are increasing in our country and across the world. Violence against women commences before birth and continues throughout life in various forms.

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Introduction: Superficial dermatophytoses constitute a common and growing problem in India. However, the associated impact on the affected individuals' quality of life (QoL) has rarely been investigated.

Aim: To assess the quality of life of patients with different dermatophytoses.

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One of the canonical features of the current outbreak of dermatophytosis in India is its unresponsiveness to treatment in majority of cases. Though there appears to be discordance between in vivo and in vitro resistance, demonstration of in vitro resistance of dermatophytes to antifungals by antifungal susceptibility testing is essential as it may help in appropriate management. The practical problem in the interpretation of antifungal susceptibility testing is the absence of clinical breakpoints and epidemiologic cutoff values.

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Trichophyton (T.) mentagrophytes now accounts for an overwhelming majority of clinical cases in India, a new "Indian genotype" (T. mentagrophytes ITS genotype VIII) having been isolated from skin samples obtained from cases across a wide geographical distribution in this country.

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Dermatophytosis has attained unprecedented dimensions in recent years in India. Its clinical presentation is now multifarious, often with atypical morphology, severe forms and unusually extensive disease in all age groups. We hesitate to call it an epidemic owing to the lack of population-based prevalence surveys.

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A rather quick change in epidemiological shift from Trichophyton rubrum to Trichophyton mentagrophytes (ITS genotype VIII), several changes in clinical presentation of superficial dermatophytoses and the the response/ the lack of it, makes this current epidemic very interesting and novel. We present here some of the relatively less discussed variants that have been described under the broad terms of tinea corporis and tinea faceie. Many of them are found to occur uncharacteristically frequently and some in areas that were never described.

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Background: An alarming increase in recalcitrant dermatophytosis has been witnessed in India over the past decade. Drug resistance may play a major role in this scenario.

Objectives: The aim of the present study was to determine the prevalence of in vitro resistance to terbinafine, itraconazole and voriconazole in dermatophytes, and to identify underlying mutations in the fungal squalene epoxidase (SQLE) gene.

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Background: Itch is an integral part of clinical picture of superficial dermatophytoses which constitute a common and growing problem in India.

Objectives: The study aimed to evaluate the prevalence, intensity and clinical characteristics of itch in superficial dermatophytosis.

Methods: The data concerning disease history and clinical type of dermatophytosis were obtained.

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The disease burden of chronic-relapsing and therapy-refractory superficial dermatophytosis dramatically increased in India within the past 5-6 years. In order to evaluate the prevalence of this trend, 201 skin scrapings were collected from patients from all parts of India and were tested for dermatophytes using both fungal culture and a PCR-ELISA directly performed with native skin scrapings. Fungal culture material was identified by genomic Sanger sequencing of the internal transcribed spacer (ITS) region and the translation elongation factor (TEF)-1α gene.

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