Investigation of transient extreme events in a mutually coupled star network of theoretical Brusselator system.

In this article, we present evidence of a distinct class of extreme events that occur during the transient chaotic state within network modeling using the Brusselator with a mutually coupled star network. We analyze the phenomenon of transient extreme events in the network by focusing on the lifetimes of chaotic states. These events are identified through the finite-time Lyapunov exponent and quantified using threshold and statistical methods, including the probability distribution function (PDF), generalized extreme value (GEV) distribution, and return period plots.

Piperine's potential in treating polycystic ovarian syndrome explored through in-silico docking.

Polycystic Ovarian Syndrome (PCOS) is a multifaceted metabolic and hormonal condition that impacts women in their procreative ages, identified by ovarian dysfunction, hyperandrogenaemia overweight and insulin insensitivity. The piperine, an important alkaloid compound of black pepper has shown promise in modulating various physiological processes. In this work, employed computational docking studies to explore the potential of piperine as a treatment for PCOS.

Impact of Gd doping on structural and magnetic characteristics of SrFeOperovskite nanomaterial.

The SrFeOnanoparticles doped with 5% and 10% Gd were synthesized using the solution combustion method. The phase formation of the synthesized nanoparticles was confirmed by powder x-ray diffraction analysis. Field emission scanning electron microscope and HRTEM were employed to examine the morphology of the samples, revealing well-ordered, agglomerated nanoparticles.

Biological synthesis of silver nanoparticles using Senna auriculata flower extract for antibacterial activities.

In this study, biological synthesis of silver nanoparticles (AgNPs) using Senna auriculata flower extract for antibacterial activities was reported. The silver spectra compared to the plant extract show a rightward shift in AgNP peaks, indicating successful nanoparticle formation. The absorption band at 302 nm and the disappearance or shift of other peaks further confirm the synthesis.

Bis[μ-3-(pyridin-2-yl)pyrazolato]bis-[acetato-(3,5-dimethyl-1-pyrazole)-nickel(II)].

The title compound, [Ni(CHN)(CHO)(CHN)] or [Ni(-OOCCH)(2-PyPz)(MePzH)] () [2-PyPz = 3-(pyridin-2-yl) pyrazole; MePzH = 3,5-dimethyl pyrazole] was synthesized from Ni(OOCCH)·4HO, 2-PyPzH, MePzH and tri-ethyl-amine as a base. Compound {[Ni(CHNNiO)]} at 100 K has monoclinic (2/) symmetry and the mol-ecules have crystallographic inversion symmetry. Mol-ecules of comprise an almost planar dinuclear Ni core with an NO coordination environment.

Green synthesis of silver and copper nanoparticles and their composites using leaf extract displayed enhanced antibacterial, antioxidant and anticancer potentials.

Green-synthesized silver and copper nanoparticles (NPs), along with their composites, exhibit various biological activities. (Holy basil), traditionally used as medicine in South Asia, treats respiratory disorders, digestive issues, skin diseases and inflammatory conditions. Modern scientific studies support these bioactivities; however, no studies have investigated their bioactivity in combination with NPs.

Phytochemical composition, simulated digestive bioaccessibility and cytotoxicity of Ficus auriculata Lour. fruits: In vitro and in silico insights.

Ficus auriculata Lour. (Moraceae) is an underutilized wild edible fruit widely consumed for its nutritional properties. The present study aimed to determine the phytochemical composition and in vitro antioxidant, enzyme inhibitory, anti-inflammatory and anti-cancerous properties of the F.

Exploring methandienone metabolites generated via homogenized camel liver: Advancements for anti-doping applications through High Resolution-Liquid Chromatography Mass Spectrometry analysis.

Rationale: Anabolic steroids, also known as anabolic-androgenic steroids (AAS), encompass steroidal androgens such as testosterone, as well as synthetic counterparts with similar structures and effects. The misuse of AAS has increased over the years, leading to ethical and welfare concerns in sports. The World Anti-Doping Agency (WADA) and the International Federation for Equestrian Sports (FEI) have banned AAS in relevant sports.

A critical review on pharmacological properties of sulfated polysaccharides from marine macroalgae.

The marine ecosystem contains an assorted range of organisms, among which macroalgae stands out marine resources as an invaluable reservoir of structurally diverse bioactive compounds. Marine macroalgae are considered as primary consumers have gained more attention for their bioactive components. Sulfated polysaccharides (SPs) are complex polymers found in macroalgae that play a crucial role in their cell wall composition.

Anticandidal Properties of among the Salt Marsh Plants Collected from Palk Bay and the Gulf of Mannar Coast, Southeastern India.

Tidal wetlands, commonly known as salt marshes, are highly productive ecosystems in temperate regions worldwide. These environments constitute a unique flora composed primarily of salt-tolerant herbs, grasses, and shrubs. This study investigated the therapeutic properties of ten salt marsh plants collected mainly from Palk Bay and Mannar Gulf against Candida disease.

In situ bioaccumulation of metals by Prosopis juliflora and its detoxification potential at the metal contaminated sites.

Heavy metals emanate from diverse anthropogenic activities and the top soil in the vicinity of these activities acts as an immediate sink and facilitates diffusion of heavy metals into the food chain. In the semi-arid plains of India, Prosopis juliflora is the most common and dominant weed along the motorways and barren lands including industrial environs. This investigation hypothesizes the adaptive nature of Prosopis juliflora in the metal enriched soils and attempts to understand its hyper-accumulating potential of metals besides bioconversion/detoxification capability.

Intestinal parasitic co-infections associated with Helicobacter pylori among paediatric patients with gastrointestinal illness attending a general hospital in southern Ethiopia.

Background: Concurrent infections or co-infections caused by intestinal parasites and Helicobacter pylori are quite rampant in paediatrics living in endemic areas of sub-Saharan Africa, including Ethiopia, and if left untreated, can result in severe complications and hence must be addressed to ensure their health and well-being.

Objectives: To determine the prevalence of intestinal parasitic and H. pylori co-infections and associated factors among paediatric patients with gastrointestinal symptoms who attended the Arba Minch General Hospital (AMGH), Arba Minch, southern Ethiopia, from September to November 2020.

Realization of logic gates in bi-directionally coupled nonlinear oscillators.

Implementation of logic gates has been investigated in nonlinear dynamical systems from various perspectives over the years. Specifically, logic gates have been implemented in both single nonlinear systems and coupled nonlinear oscillators. The majority of the works in the literature have been done on the evolution of single oscillators into OR/AND or NOR/NAND logic gates.

Minor limonoid constituents from by simultaneous isolation using supercritical fluid chromatography and their biological activities.

This study reports simultaneous isolation of three new limonoids (1-3), six known regio isomers (6, 7, 9-12), and three more known limonoids (4, 5, 8) from () seeds. Structures of these compounds were determined extensive study of their 1D/2D-NMR and mass spectral data. Known limonoids (4-12) were identified by comparing their physical and spectroscopic data with literature values.

Induction and comparative resuscitation of viable but nonculturable state on Vibrio parahaemolyticus serotypes O3:K6 and O1:K25.

Vibrio parahaemolyticus, an important food-borne pathogens found to be associated with seafoods and marine environs. It has been a topic of debate for many decades that most pathogens are known to enter a viable but nonculturable (VBNC) state under cold temperature and nutrient limited conditions. The present study examined the time required for the induction of VBNC state and the revival strategies of both the endemic O3:K6 and O1:K25 sporadic strains of V.

Coconut husk waste products valorization for fabrication of luminescent titanium dioxide NPs as powerful tool for photodecomposition and food born infection: A sustainable strategy.

Fabricating metal oxide nanoparticles has garnered much attention lately because creating safe chemicals, sustainable materials, economic processes, and renewable resources is becoming increasingly important. This research shows how TiO nanoparticles (NPs) could be generated in an ecologically responsible way using waste coconut husk with the help of tender coconut. This extract functions as both a reducing agent and a sealing agent.

Phytoconstituent Profiling and Antifungal Efficacy of Artemisia absinthium L.: Towards Sustainable Bio-Fungicide Development.

Natural alternatives to synthetic fungicides are gaining prominence as the focus sharpens on developing protective products. In this regard, the present study aimed to discern the antifungal potential of Artemisia absinthium L., a traditional medicinal plant native to Kashmir, by identifying its key phytoconstituents.

Doxorubicin downregulates cell cycle regulatory hub genes in breast cancer cells.

Breast cancer (BC) is the leading commonly diagnosed cancer in the world, with complex mechanisms underlying its development. There is an urgent need to enlighten key genes as potential therapeutic targets crucial to advancing BC treatment. This study sought to investigate the influence of doxorubicin (DOX) on identified key genes consistent across numerous BC datasets obtained through bioinformatic analysis.

Overexpression of EaALDH7, an aldehyde dehydrogenase gene from Erianthus arundinaceus enhances salinity tolerance in transgenic sugarcane (Saccharum spp. Hybrid).

Aldehyde Dehydrogenases (ALDH), a group of enzymes, are associated with the detoxification of aldehydes, produced in plants during abiotic stress conditions. Salinity remains a pivotal abiotic challenge that poses a significant threat to cultivation and yield of sugarcane. In this study, an Aldehyde dehydrogenase gene (EaALDH7) from Erianthus arundinaceus was overexpressed in the commercial sugarcane hybrid cultivar Co 86032.

A systematic review on the impact of micro-nanoplastics on human health: Potential modulation of epigenetic mechanisms and identification of biomarkers.

Epigenetic-mediated modifications, induced by adverse environmental conditions, significantly alter an organism's physiological mechanisms. Even after elimination of the stimulus, these epigenetic modifications can be inherited through mitosis, thereby triggering transgenerational epigenetics. Plastics, with their versatile properties, are indispensable in various aspects of daily life.

One-Pot Sustainable Synthesis of Highly Substituted Pyrimidines via Acceptorless Dehydrogenative Annulation of Alcohols Using Pincer Ni(II)-NNS Catalysts.

We report an efficient and sustainable synthesis of highly substituted pyrimidines promoted by nickel(II)-NNS pincer-type complexes via acceptorless dehydrogenative annulations of readily available alcohols, malononitrile, and guanidine/benzamidine salt under eco-friendly conditions for the first time. Different sets of Ni(II) complexes () encapsulated in NNS pincer-type thiosemicarbazone ligands have been synthesized and authenticated by analytical and spectroscopic (Fourier transform infrared, nuclear magnetic resonance, and high-resolution mass spectrometry) techniques. The solid state three-dimensional structure of a representative complex () has been determined with the aid of single crystal XRD analysis and confirms a square planar architecture around the nickel ion.

NNO Pincer-Supported Pd(II)-Catalyzed Reductive N-Alkylation of Challenging Nitroarenes with Alcohols via Borrowing Hydrogen Strategy.

A sustainable catalytic synthesis of selective monoalkylated amines from nitroarenes and alcohols by new palladium(II)-NNO pincer-type complexes has been described. Herein, a series of Pd(II) complexes [Pd(NNO)PPh] (-) are synthesized and characterized by analytical and spectroscopic (IR, NMR, and HR-MS) methods. The solid-state molecular structures of two complexes are established by X-ray single-crystal diffraction.

Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations.

In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile, and genetic changes in JN.

Typical pneumonia among human immunodeficiency virus-infected patients in public hospitals in southern Ethiopia.

Background: Typical pneumonia is a pressing issue in the treatment of human immunodeficiency virus (HIV) patients, especially in Sub-Saharan Africa, where it remains a significant menace. Addressing this problem is crucial in improving health outcomes and the reduction of the burden of diseases in this vulnerable category of patients.

Objective: To determine the prevalence of community-acquired typical pneumonia among HIV patients in Public Hospitals in southern Ethiopia.

Analysis of antiproliferative activity of new half-sandwich arene Ru(II) thiophene based aroylhydrazone complexes.

Efforts in researching the efficient anti-tumor properties of three novel arene ruthenium(II) complexes incorporating thiophene-based aroylhydrazone ligands have been undertaken. The complexes' elemental composition was [(--cymene)Ru(L)Cl]. They were comprehensively characterized through elemental and spectroscopic analyses (FT-IR, UV-vis, NMR, and HR-MS).