Facile Synthesis and Characterization of Chitosan Functionalized Silver Nanoparticles for Antibacterial and Anti-Lung Cancer Applications.

In the treatment of bacterial contamination, the problem of multi-drug resistance is becoming an increasingly pressing concern. Nanotechnology advancements enable the preparation of metal nanoparticles that can be assembled into complex systems to control bacterial and tumor cell growth. The current work investigates the green production of chitosan functionalized silver nanoparticles (CS/Ag NPs) using and their inhibition efficacy against bacterial pathogens and lung cancer cells (A549).

Observer-based state estimation for discrete-time semi-Markovian jump neural networks with round-robin protocol against cyber attacks.

This paper investigates an observer-based state estimation issue for discrete-time semi-Markovian jump neural networks with Round-Robin protocol and cyber attacks. In order to avoid the network congestion and save the communication resources, the Round-Robin protocol is used to schedule the data transmissions over the networks. Specifically, the cyber attacks are modeled as a set of random variables satisfying the Bernoulli distribution.

Sustainable assessment of plastic and mixed waste disposal problem during COVID-19 pandemic: an integrated multi-criteria decision-making approach.

This article focuses on India's inorganic solid waste disposal problem, with a particular emphasis on plastic and mixed waste. It aims to identify the current COVID-19 pandemic situation as well as provide a suitable disposal technique for wastes that are specifically related to municipal solid waste management. We propose an integrated approach to disposing of paper and plastic and mixed wastes in an interval-valued q-rung orthopair fuzzy (IVq-ROF) environment for this problem.

Selection of suitable biomass conservation process techniques: a versatile approach to normal wiggly interval-valued hesitant fuzzy set using multi-criteria decision making.

A country that relies on developing industrialization and GDP requires a lot of energy. Biomass is emerging as one of the possible renewable energy resources that may be used to generate energy. Through the proper channels, such as chemical, biochemical, and thermochemical processes, it can be turned into electricity.

An innovative probabilistic hesitant fuzzy set MCDM perspective for selecting flexible packaging bags after the prohibition on single-use plastics.

The probabilistic hesitant elements (PHFEs) are a beneficial augmentation to the hesitant fuzzy element (HFE), which is intended to give decision-makers more flexibility in expressing their biases while using hesitant fuzzy information. To extrapolate a more accurate interpretation of the decision documentation, it is sufficient to standardize the organization of the elements in PHFEs without introducing fictional elements. Several processes for unifying and arranging components in PHFEs have been proposed so far, but most of them result in various disadvantages that are critically explored in this paper.

Ipomoea pes-tigridis L. extract accelerates wound healing in Wistar albino rats in excision and incision models.

Ethnopharmacological Relevance: An annual herb, Ipomoea pes-tigridis L. (Convolvulaceae) is widely used for its anti-inflammatory and anti-spasmodic properties in traditional medicine. As well as treating wounds, fever, skin disorders, and other ailments, it is also used for other purposes.

Conservation linkages of endangered medicinal plant and exploration of phytochemicals, pharmaceutical screening and in silico validation against diabetics using in vivo wild and in vitro regenerated plant Wight.

Unlabelled: Wight. is an important endangered medicinal plant belonging to the family Asclepiadaceae. In this study, an efficient protocol has been developed for using nodal explants for callus induction and direct organogenesis.

Efficiency of hematological, enzymological and oxidative stress biomarkers of Cyprinus carpio to an emerging organic compound (alphamethrin) toxicity.

Alphamethrin is one of the extensively used pyrethroids. Its non-specific mode-of-action might affect the non-target-organisms. Its toxicity data on aquatic organisms are lacking.

Ecotoxicological evaluation of the UV-filter octocrylene (OC) in embryonic zebrafish (Danio rerio): Developmental, biochemical and cellular biomarkers.

Octocrylene (OC), an UV-filter (OUVF) is used in many cosmetic products to protect the skin against the harmful effects of UV radiation. Octocrylene has been detected in the environment and become an emerging contaminant of concern. However, the eco-toxicological data on octocrylene and their molecular effects and mechanism of action on freshwater fish are very limited.

Proteomic investigation and understanding on IgY purification and product development.

An increasing demand for the development of immunoglobin Y (IgY) illustrates the necessity of the component analysis in the process of conduction and quality control. This study investigated the proteomic changes in crude IgY extracts and purified IgY products obtained by sequential polyethylene glycol precipitation (PEG) of egg yolks followed by human mycoplasma protein-based affinity chromatography compared with intact egg yolks. After confirming the extraction efficiency and purity by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis, liquid chromatography tandem-mass spectrometry (LC-MS/MS) was performed with samples including fresh yolk, IgY extracted product and purified product.

Toxicogenomic analysis of physiologically important metals: An integrated in silico approach.

Biologically important metals regulate cellular homeostasis in living systems. Anthropogenic exposure to these metals can cause adverse effects, including an increased incidence of diseases in humans such as cancer, lung, and cardiovascular defects. However, the effects of metals and the common genes/signaling pathways involved in metal toxicity have not been elucidated.

Development of silver oxide-loaded reduced graphene oxide nanohybrids for enhanced photocatalytic activity under visible light in aqueous solutions.

We report on the synthesis of silver oxide/reduced graphene oxide nanocomposites (Ag/rGO NCs) using a hydrothermal technique. This paper presents a simple method for synthesizing Ag/rGO hybrid nanocomposites, which can be used for environmentally treating hazardous organic pollutants. The photocatalytic degradation of model artificial Rhodamine B dye and bisphenol A was assessed under visible light illumination.

Predicting the relationship between pesticide genotoxicity and breast cancer risk in South Indian women in in vitro and in vivo experiments.

Breast cancer is the third most common cancer in women after skin and lung cancer. Pesticides are of interest in etiologic studies of breast cancer because many pesticides mimic estrogen, a known breast cancer risk factor. In this study, we discerned the toxic role of the pesticides atrazine, dichlorvos, and endosulfan in inducing breast cancer.

Calculation of set-up margin in frameless stereotactic radiotherapy accounting for translational and rotational patient positing error.

Context: Rotation corrected set-up margins in stereotactic radiotherapy (SRT).

Aims: This study aimed to calculate the rotational positional error corrected set-up margin in frameless SRT.

Settings And Design: 6D setup errors for the steriotactic radiotherapy patients were converted to 3D translational only error mathematically.

Isolation of 5' regulatory region of gene and its functional characterization through transient expression analysis in tobacco and sugarcane.

Unlabelled: Chilling Tolerant Divergence 1 () gene consists of Golgi pH Receptor (GPHR) as well as Abscisic Acid-linked G Protein-Coupled Receptor (ABA_GPCR), which are the major transmembrane proteins in plants. This gene expression has been found to be differentially regulated, under various stress conditions, in wild -related genera, , compared to commercial sugarcane variety. In this study, Rapid Amplification of Genomic Ends (RAGE) technique was employed to isolate the 5' upstream region of COLD1 gene to gain knowledge about the underlying stress regulatory mechanism.

Photocatalytic degradation of organic pollutants and inactivation of pathogens under visible light via SnO/rGO composites.

The domains of environmental cleanup and pathogen inactivation are particularly interesting in nanocomposites (NCs) due to their exceptional physicochemical properties. Tin oxide/reduced graphene oxide nanocomposites (SnO/rGO NCs) have potential uses in the biological and environmental fields, but little is known about them. This study aimed to investigate the photocatalytic activity and antibacterial efficiency of the nanocomposites.

Paeoniflorin found in Paeonia lactiflora root extract inhibits melanogenesis by regulating melanin-related signal transduction in B16F10 cells.

Background: Skin pigmentation is modulated by various processes, with melanogenesis playing a key role. Melanin is synthesized by the catalysis of melanogenesis-related enzymes, such as tyrosinase and tyrosine-related proteins TRP-1 and TRP-2. Paeoniflorin is the main bioactive component of Paeonia suffruticosa Andr.

Assessment of Inter-relationship between Anemia and COPD In Accordance with Altitude.

Background: Anemia, a common blood disorder has been analysed for the risk for chronic obstructive pulmonary disease (COPD), a predominant respiratory condition. The COPD patients have been found to have anemia due to inflammation, accounting for about 7.5-33%.

Influence of Borassus flabellifer Endocarps Hydrolysate on Fungal Biomass and Fatty Acids Production by the Marine Fungus Aspergillus sp.

Polyunsaturated Fatty Acids (PUFAs) are important nutrients for human health. We aimed to evaluate the efficiency of marine water fungus Aspergillus sp. (Accession no: MZ505709) for lipid biosynthesis.

Bipolar intuitionistic fuzzy graph based decision-making model to identify flood vulnerable region.

Bipolar intuitionistic fuzzy graphs (BIFG) are an extension of fuzzy graphs that can effectively capture uncertain or imprecise information in various applications. In graph theory, the covering, matching, and domination problems are benchmark concepts applied to various domains. These concepts may not be defined precisely using a crisp graph when the vertices and edges are more uncertain.

Nanoencapsulation of garlic essential oil using chitosan nanopolymer and its antifungal and anti-aflatoxin B1 efficacy in vitro and in situ.

The present study investigated the comparative efficacy of garlic essential oil (GEO) and its nanoencapsulated within chitosan nanomatrix (GEO-CSNPs) as a novel preservative for the protection of stored food commodities from fungal infestations, aflatoxin B1 (AFB1) contamination and lipid peroxidation against a toxigenic strain of Aspergillus flavus. GC-MS examination of GEO showed the presence of allyl methyl tri-sulfide (23.10 %) and diallyl sulfide (19.

Virtual screening of FOXO3a activators from natural product-like compound library.

FOXO3a is an inevitable transcription factor, which is involved in the regulation of biological processes such as proliferation, DNA damage repair, cell cycle arrest and cell death. Previous studies confirmed that FOXO3a is an excellent tumor suppressor and in cancer cells, it gets phosphorylated followed by proteasomal degradation. FOXO3a is found to be inactivated in cancer cells, whereas in normal cells it gets activated and upregulates its downstream targets, which induces apoptotic pathways.