Does Illness Perception Predict Hopelessness and Death Anxiety in Palliative Care Patients?

Illness perception is crucial in how patients navigate health challenges. Investigating if it predicts hopelessness and death anxiety is vital, especially in palliative care where these burdens are common. This descriptive, cross-sectional study was conducted with 129 patients receiving treatment in the palliative care clinics of a university hospital.

Short-term effects of dapagliflozin on biomarkers of bone and mineral metabolism in patients with diabetic kidney disease: A prospective observational study.

Background: There is still a lack of information regarding the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on bone and mineral metabolism in patients with diabetes and chronic kidney disease (CKD). Therefore, we aimed to investigate the effects of SGLT2i in a cohort of patients suffering from diabetic kidney disease (DKD).

Methods: In this prospective observational study, patients with type 2 diabetes and biopsy-proven diabetic nephropathy or presumptive DKD with eGFR levels ≥20 ml/min/1.

Multimorbidity clusters and their contribution to well-being among the oldest old: Results based on a nationally representative sample in Germany.

Aim: Our aim was to identify multimorbidity clusters and, in particular, to examine their contribution to well-being outcomes among the oldest old in Germany.

Methods: Data were taken from the large nationally representative D80+ study including community-dwelling and institutionalized individuals aged 80 years and over residing in Germany (n = 8,773). The mean age was 85.

Therapeutic Potential of Stromal Vascular Fraction in Enhancing Wound Healing: A Preclinical Study.

Background: Adipose tissue provides an abundant source of stromal vascular fraction (SVF) cells for immediate administration. It can also give rise to many multipotent adipose-derived stromal cells. SVF is the population of cells obtained from mechanical or enzymatic digestion of lipoaspirate with no necessity for cell culture or expansion.

Lithium Intoxication After Sleeve Gastrectomy: A Case Report and Differential Diagnosis.

Bariatric surgery rates have been increasing in the treatment of obesity worldwide recently. In addition to many physical changes after bariatric surgery, the bioavailability of medications can also be significantly affected. In this article, we present a 51-year-old female patient diagnosed with lithium toxicity after sleeve gastrectomy surgery.

Evaluation of the Awareness and Anxiety Levels and Oral Hygiene Habits of University Students During the Coronavirus Disease 2019 (COVID-19) Pandemic.

Aim: The aim of this study was to evaluate the awareness and anxiety levels and oral hygiene habits of university students during the coronavirus disease 2019 (COVID-19) pandemic.

Materials And Methods: A total number of 560 university students were included at different education levels. Sociodemographic data regarding age, gender, current school level, family income, and smoking frequency status were obtained.

Investigation of Trace and Macro Element Contents in Commercial Cat Foods.

Background: Nutritional profiles and guidelines are determined by various associations to ensure optimum health of cats and provide pet food manufacturers nutritional recommendations to ensure the well-balanced and nutritionally adequate pet food.

Objectives: It was aimed to determine some trace elements and macro minerals in prescription and non-prescription dry cat foods and compare the contents with the suggested guidelines to evaluate the potential in-compliance.

Methods: A total of 96 dry cat foods were evaluated.

Association of Proximal Vessel Tortuosity with Technical Success and Clinical Outcomes: Analysis From the Progress-CTO Registry.

Background: Proximal vessel tortuosity can hinder wiring and equipment delivery during chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Aims: We sought to examine the association of proximal vessel tortuosity with the short and long-term outcomes of patients undergoing CTO PCI.

Methods: We examined the association of proximal vessel tortuosity with clinical outcomes in patients who underwent CTO PCI at 50 US and non-US centers between 2012 and 2024.

Depressor Labii Inferioris Muscle Palsy After Chin Augmentation.

The depressor labii inferioris (DLI) muscle helps to lower and turn the lower lip outward and receives innervation from the marginal mandibular branch of the facial nerve. Paralysis of this muscle is a rare but potential complication of chin augmentation injections. Paralysis of the DLI causes symptoms such as difficulty smiling on the affected side, difficulty speaking clearly, and facial asymmetry, especially when smiling.

Formulation of nasal analgesic sprays with diclofenac sodium, ibuprofen, paracetamol, and evaluation of toxicity.

Objective: Intranasal analgesic sprays represent a safe, efficacious method for pain relief, with a shorter working time compared to oral painkillers. This study aimed to develop nasal sprays using commonly available over-the-counter analgesics, providing an alternative treatment option that is more convenient and potentially more effective in managing pain, particularly in pediatric patients.

Methods: Three different nasal spray formulations with the contents of diclofenac sodium, ibuprofen, and paracetamol were created, and characterization studies were completed.

Impact of diabetes on epicardial reperfusion and mortality in a contemporary STEMI population undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry.

Background And Aim: Diabetes has been shown in last decades to be associated with a significantly higher mortality among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary PCI (PPCI). Therefore, the aim of current study was to evaluate the impact of diabetes on times delays, reperfusion and mortality in a contemporary STEMI population undergoing PPCI, including treatment during the COVID pandemic.

Methods And Results: The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry involving PPCI centers from Europe, Latin America, South-East Asia and North-Africa, including patients treated from 1st of March until June 30, 2019 and 2020.

Chenodeoxycholic acid alleviated the cyclosporine-induced nephrotoxicity by decreasing oxidative stress and suppressing renin-angiotensin system through AT2R and ACE2 mRNA upregulation in rats.

Oxidative stress, inflammation and renin-angiotensin system (RAS) activation play an important role in the nephrotoxicity which is caused by the long-term use of the immunosuppressive drug cyclosporine (CsA). This study investigates whether chenodeoxycholic acid (CDCA), an endogenous farnesoid X receptor (FXR) agonist with antioxidant and anti-inflammatory effects, modulates CsA nephrotoxicity. CsA (25 mg/kg/day; s.

The Effect of Immediate Dentin Sealing Using Different Universal Adhesives on the Bond Strength of Pretreated Monolithic Zirconia to Dentin and Microscopic Morphological Alterations.

This study evaluated the effects of immediate dentin sealing (IDS) using different universal adhesives on microtensile bond strength (μTBS) of pretreated monolithic translucent tetragonal polycrystalline zirconia-based CAD/CAM restoration to dentin and microscopic morphological alterations. Mid-coronal dentin were obtained from 32 human molars and randomly allocated into 8 groups according to the presence/absence of IDS, universal adhesives for IDS (Single Bond Universal/SBU, Clearfil Quick Bond/CUQ, Optibond Universal/OBU) and zirconia surface pretreatments (tribochemical silica coating-30 μm CoJet particles/TSC, sandblasting-50 μm AlO/SB): Group TSC, Group TSC+SBU, Group TSC+CUQ, Group TSC+OBU, Group SB, Group SB+SBU, Group SB+CUQ, Group SB+OBU. CAD/CAM restorations (Lava Plus High Translucency Zirconia Disc) were produced, luted, and subjected to 10.

Sample Preparation Techniques for Analysis of Endocannabinoids in Biological Fluids and Tissues.

This review discusses various sample pretreatment methods for the analytical assessment of endocannabinoids in biological fluids and tissues. Techniques like liquid-liquid extraction, protein precipitation, SALLE, SPME, and micro-solid phase extraction (µ-SPE) are investigated. The findings show that SALLE and SPME provide phase separation as a fast and environmentally friendly method and allow high sensitivity in the analyses.

Assessment of erectile dysfunction prevalence and associated factors in hypertensive men.

Background: This study aimed to assess the prevalence of erectile dysfunction and identify associated factors among male patients with hypertension.

Methods: A cross-sectional descriptive study was conducted. Data were gathered from 223 individuals aged 18 and above, solely diagnosed with hypertension.

Effects of Nutritional Protocol Changes on Hemodialysis Adequacy and Patient Health During the COVID-19 Pandemic.

BACKGROUND During the COVID-19 pandemic, strict feeding restrictions were implemented in many dialysis centers to minimize transmission between patients. This study aims to evaluate the effects of these feeding restrictions on dry weight, intradialytic hypotension (IDH), and dialysis adequacy in hemodialysis patients. MATERIAL AND METHODS In this retrospective single-center study involving 76 hemodialysis patients, data from 2 consecutive 6-month periods were analyzed: the first before the COVID-19 pandemic when intradialytic nutrition was supported, and the second during the pandemic when intradialytic nutrition was restricted.

Evaluation of White Matter Integrity by Using Diffusion Tensor Imaging in Patients with Presbycusis.

Rationale And Objectives: This study aims to evaluate white matter microstructure integrity in patients diagnosed with presbycusis (age-related hearing loss) using diffusion tensor imaging (DTI) and to investigate the relationship between DTI parameters and hearing loss severity.

Materials And Methods: Patients aged 50 and above with presbycusis (pure-tone average [PTA] ≥20dB) were categorized as mild (PTA 20-34dB), moderate (PTA 35-49dB), or severe (PTA ≥50dB). Fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were measured in 16 white matter regions.