7 results match your criteria: "Bethanian Hospital[Affiliation]"
Am J Psychiatry
May 2024
Department of Addictive Behavior and Addiction Medicine (Hoffmann, Gerhardt, Bach, Boroumand-Jazi, Aslan, Karl, Mazza, Reichl, Zaiser, Zimmermann, Vollstädt-Klein, Kiefer, Lenz), Department of Biostatistics (Hoffmann, Reinhard), Department of Psychiatry and Psychotherapy (Kuehner, Ganz, Ebner-Priemer, Meyer-Lindenberg, Tost, M. Reichert), Department of Clinical Psychology (Pinger, Weiss, Kirsch), Institute of Psychopharmacology (Müller, Sommer, Spanagel), Department of Child and Adolescent Psychiatry and Psychotherapy (Banaschewski), and Department of Genetic Epidemiology in Psychiatry (Rietschel, Witt), Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Mannheim Center for Translational Neurosciences, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (Vollstädt-Klein, Meyer-Lindenberg, Kiefer, Lenz); Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany (Mühle, Kornhuber, Müller); Mental mHealth Lab, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (D. Reichert, Ebner-Priemer, M. Reichert); Department of eHealth and Sports Analytics, Faculty of Sports Science, Ruhr University Bochum, Bochum, Germany (D. Reichert, M. Reichert); Center for Information Services and High Performance Computing (Aguilera, Strehle, Wieder) and Department of Psychiatry and Psychotherapy (Belanger, Fischbach, Großkopf, Hentschel, Steffen, Zech, Deserno, Smolka), Technische Universität Dresden, Dresden, Germany; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin (Bahr, Ebrahimi, Garbusow, Heigert, Liu, Pelz, Riemerschmid, Rosenthal, Wedemeyer, Wenzel, Walter, Heinz); Department of Social and Preventive Medicine, University of Potsdam, Potsdam, Germany (Deeken, Rapp); Center for Drug Research, Universiti Sains Malaysia, Penang, Malaysia (Müller); Bethanian Hospital for Psychiatry, Psychosomatics, and Psychotherapy, Greifswald, Germany (Sommer); Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany (Zech, Deserno); Deutsches Zentrum für psychische Gesundheit (German Center for Mental Health), Partner Site Mannheim-Heidelberg-Ulm (Sommer, Spanagel, Banaschewski, Ebner-Priemer, Flor, Kirsch, Rietschel, Meyer-Lindenberg, Tost, Kiefer), Partner Site Berlin-Potsdam (Rapp, Heinz); Department of Psychology, Clinical Psychology, and Psychotherapy, MSB Medical School Berlin (Garbusow).
Objective: Alcohol use disorder (AUD) constitutes a critical public health issue and has sex-specific characteristics. Initial evidence suggests that progesterone and estradiol might reduce or increase alcohol intake, respectively. However, there is a need for a better understanding of how the menstrual cycle in females and the ratio of progesterone to estradiol in females and males influence alcohol use patterns in individuals with AUD.
View Article and Find Full Text PDFAlcohol Alcohol
November 2023
Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, Heidelberg University, J 5, 68159 Mannheim, Germany.
Craving for alcohol is an important diagnostic criterion in alcohol use disorder (AUD) and an established predictor of future relapse. The 5-item Penn Alcohol Craving Scale (PACS) is one of the most widely used questionnaires to quantify craving and has been translated into different languages. It is assumed that the PACS constitutes one factor, although theoretical considerations suggest an additional second factor.
View Article and Find Full Text PDFTransl Psychiatry
April 2023
Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus of the Technische Universität Dresden, Dresden, Germany.
This registered clinical trial sought to validate a laboratory test system devised to screen medications for alcoholism treatment (TESMA) under different contingencies of alcohol reinforcement. Forty-six nondependent, but at least medium-risk drinkers were given the opportunity to earn intravenous infusions of ethanol, or saline, as rewards for work in a progressive-ratio paradigm. Work demand pattern and alcohol exposure dynamics were devised to achieve a gradual shift from low-demand work for alcohol (WFA) permitting quickly increasing breath alcohol concentrations (BrAC) to high-demand WFA, which could only decelerate an inevitable decrease of the previously earned BrAC.
View Article and Find Full Text PDFBMJ Ment Health
February 2023
Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty of Mannheim, Heidelberg University, Mannheim, Germany.
Background: Cue reactivity, the enhanced sensitivity to conditioned cues, is associated with habitual and compulsive alcohol consumption. However, most previous studies in alcohol use disorder (AUD) compared brain activity between alcohol and neutral conditions, solely as cue-triggered neural reactivity.
Objective: This study aims to find the neural subprocesses during the processing of visual alcohol cues in AUD individuals, and how these neural patterns are predictive for relapse.
Alcohol Alcohol
March 2023
Amsterdam UMC, Location Academic Medical Center, University of Amsterdam, Department of Psychiatry, Amsterdam Neuroscience, Meibergdreef 5, 1105AZ Amsterdam, The Netherlands.
Aims: The estimated effect of sodium oxybate (SMO) in the treatment of alcohol dependence is heterogeneous. Population severity and treatment duration have been identified as potential effect modifiers. Population severity distinguishes heavy drinking patients with <14 days of abstinence before treatment initiation (high-severity population) from other patients (mild-severity population).
View Article and Find Full Text PDFAddict Biol
January 2023
Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
A previous highly controlled pilot study revealed that body mass index (BMI) predicts outcome of in-patients with alcohol use disorder (AUD) in a sex-specific manner. We here provide translational evidence from a daily clinical routine setting and investigated whether BMI and sex interact to predict 24-month readmission risk in four naturalistic cohorts of a specialized addiction clinic (i.e.
View Article and Find Full Text PDFScand J Gastroenterol Suppl
April 1989
Dept. of Medicine, Bethanian Hospital, Hamburg, FRG.
Pharmacodynamic studies revealed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion. When administered orally as a capsule containing a granule formulation, the drug displayed modified-release properties, which led to a sustained suppression of gastric acid secretion. Clinical trials revealed that roxatidine acetate, 75 mg twice daily and 150 mg at night, was highly effective in healing duodenal and gastric ulcers and in reducing ulcer pain, over 4, 6, and 8 weeks of therapy.
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