8,472 results match your criteria: "Benign and Malignant Soft Tissue Tumors"

Articular masses comprise various disease entities including benign or malignant proliferative processes and other non-neoplastic processes such as infection, deposition diseases, vascular malformations, and other lesions. Many diseases that lead to intra-articular or para-articular masses have distinct imaging features, particularly on MRI. Radiologists can localize masses to the joint space by knowing the articular anatomy and can reach a suggested diagnosis by looking at precise imaging findings.

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Background: Tenosynovial giant cell tumor is a rare soft tissue tumor of the synovium of joint, bursae, or tendon sheath. It is divided into localized or diffuse types on the basis of the growth pattern. Localized tenosynovial giant cell tumors are usually benign and treated successfully by excision.

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Article Synopsis
  • * An 80-year-old Caucasian man experienced upper airway obstruction and significant bleeding due to a large tracheal glomus tumor, which was diagnosed as glomangioma.
  • * GTs comprise about 1.6% of soft tissue tumors, with tracheal cases posing the greatest risk of malignancy and potential airway obstruction; diagnosis is confirmed through histological analysis, and surgical resection is the main treatment.
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Introduction And Importance: Fibroepithelial polyps are rare benign lesions with uncertain origins. They are commonly found in the skin and genitourinary system. Fibroepithelial polyps in the external auditory canal are infrequent.

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  • * A 47-year-old woman with multiple UFs developed heart failure due to the tumors invading the right iliac vein and extending into the heart, but she successfully underwent a single-stage surgical resection.
  • * Post-surgery, she has survived more than 24 months with significant improvement in heart function and no recurrence of UFs, highlighting the benefits of this surgical approach.
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  • Hydatid cyst is a parasitic infection caused by tapeworm species that can sometimes occur in unusual locations, like intermuscular tissues, which can be confused with other types of tumors.
  • Diagnosing intermuscular hydatid cysts is crucial, and magnetic resonance imaging (MRI) is key for identifying their specific characteristics, as demonstrated in a reported case.
  • A 34-year-old man had a left thigh swelling for 5 years, and MRI revealed encapsulated cysts; he underwent surgery and received albendazole treatment before and after the procedure.
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Extravascular lipoma over the subclavian vein.

BMJ Case Rep

September 2024

General Surgery, Chettinad Academy of Research and Education, Kanchipuram, Tamil Nadu, India

A rare instance of extravascular lipomas located over the subclavian vein in a woman in her early 60s presented unique diagnostic and therapeutic challenges due to their close proximity to critical structures. Lipomas, which are the most commonly occurring benign soft tissue tumours, are typically composed of mature adipocytes. Although lipomas can develop in any region of the body, they are most commonly found in the subcutaneous tissues of the trunk and proximal limbs.

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Soft tissue masses are very common and may appear in the context of rheumatic diseases. They usually occur alone but may occasionally be part of the syndromes and can sometimes involve periarticular tissues. Soft tissue masses can be divided into several categories.

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Synovial sarcoma is a malignant soft tissue tumor of uncertain differentiation. It is typically seen in the deep soft tissue of the extremities; however, it has been reported to occur anywhere in the body. Synovial sarcoma by histomorphology has multiple subtypes, including monophasic spindle cell, biphasic and poorly differentiated subtypes.

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Benign glomus tumor of prostate: a case report.

BMC Urol

September 2024

Department of Radiology, Yunnan Cancer Hospital, Third Affiliated Hospital of Kunming Medical University, 519 Kunzhou Road, Xishan District, Kunming, 650118, China.

Article Synopsis
  • Glomus tumors (GT) are special growths that come from a type of tissue in the body.
  • Most of these tumors appear in soft parts of the body like arms and legs, but they can show up anywhere.
  • This text talks about a rare case of a glomus tumor found in the prostate, which is unusual.
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Myxomas are a group of benign tumors that have a common histologic appearance of fibrous and myxoid ground substance. According to literature, myxomas often occur between the ages of 30 and 50 years. Very often, intraoral soft tissue myxoma can be misinterpreted as malignant and is difficult to differentiate from other tumors with myxoid stroma.

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Urachal tumors are rare and comprise of both benign and malignant neoplasms. Epithelial origin tumors are more common than mesenchymal origin tumors. We report a case Urachal inflammatory myofibroblastic tumor (IMFT) in a 12 year old boy who presented with symptoms of lower abdominal pain and burning micturition.

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Article Synopsis
  • - Mesenchymal tumors, which arise from mesenchymal cells, can be benign or malignant and often require complex surgical procedures for treatment; however, the COVID-19 pandemic has led to a need for non-surgical alternatives due to limited surgical resources.
  • - This review discusses various non-surgical treatments, including active surveillance, cryoablation, and tyrosine kinase inhibitors, aimed at improving surgical outcomes, serving as pre-surgery bridges, or providing non-curative options when surgery isn't feasible.
  • - The Sarculator tool is mentioned as a means to personalize treatment plans for high-risk sarcoma patients, emphasizing the importance of a multidisciplinary approach in referral centers to optimize treatment strategies.
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  • - Sclerosing epithelioid fibrosarcoma (SEF) is a rare, aggressive soft tissue sarcoma typically found in middle-aged adults but has been documented in children, associated with a high rate of local recurrence and metastasis.
  • - A case study details a 10-year-old girl with Graves' disease who was diagnosed with SEF after developing a large mass in her left eye muscle, and she remained disease-free 18 months post-incomplete surgical resection and radiation therapy.
  • - The identification of SEF relies on genetic testing and immunohistochemistry for certain gene expressions, and the text suggests that DNA methylation profiling could enhance the diagnosis of pediatric sarcomas.
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Pathological crystallization within soft tissues often yields biominerals with properties differing from those of their geological or synthetic counterparts. Microcalcifications (MCs) are abundant in breast tumors, particularly in non-invasive lesions, such as ductal carcinoma (DCIS). Given the challenge of predicting DCIS progression into invasive cancer, it has been suggested that MCs can be leveraged to inform DCIS prognosis.

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Objectives: Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue neoplasm of uncertain histogenesis. Most OFMTs have benign behavior, and many harbor gene fusions involving the PHD finger protein 1 (PHF1), such as EP400::PHF1, MEAF6::PHF1, EPC1::PHF1, and PHF1::TFE3. The PHF1::TFE3 fusion is unique because PHF1 is at 5' instead of residing at 3' in the other fusions.

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Atypical Presentation of Tenosynovial Giant Cell Tumor on the Hallucal Flexor Tendon Sheath: A Case Report.

J Am Podiatr Med Assoc

September 2024

†Department of Pathology and Laboratory Medicine, Temple University School of Podiatric Medicine, Philadelphia, PA. Dr. Arriola is now with Department of Pathology, Cooper University Health Care, Camden, NJ, and Cooper Medical School of Rowan University, Camden, NJ.

Article Synopsis
  • - Tenosynovial giant cell tumor (TGCT) is a rare, usually benign neoplasm that can be aggressive, found mainly in joints and tendon sheaths, particularly in the fingers and less often in the feet.
  • - TGCT is classified into two subtypes: localized and diffuse, and its symptoms can mimic other conditions like lipomas or ganglion cysts, making diagnosis tricky.
  • - A case study on a 30-year-old woman presented with pain and a mass in her foot, which was diagnosed as TGCT after surgical excision and testing, highlighting the importance of advanced imaging and histology for accurate diagnosis and treatment.
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Postauricular Myofibroma of the Facial Canal: A Case Report.

J Audiol Otol

October 2024

Department of Special Surgery, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Myofibromatosis is a proliferative disorder characterized by the development of soft tissue neoplasms referred to as myofibromas that predominantly occur in infants and young children. These lesions have been described using varied terminologies since they were first reported in 1951. However, these neoplasms are histopathologically characterized by benign fibroblast and myofibroblast proliferation containing a biphasic presentation of spindle-shaped cells surrounding a central zone of less differentiated cells arranged in a hemangiopericytoma-like pattern in all cases.

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Risk factors and incidence of oral tumors: Findings from a longitudinal population-based study.

Oral Dis

September 2024

The Shapiro Family Laboratory of Viral Oncology and Aging Research, School of Dentistry, University of California Los Angeles, Los Angeles, California, USA.

Objective: This study investigated risk factors contributed to benign and malignant oral tumors using longitudinal cohort big data.

Materials And Methods: We included individuals aged ≥40 years who participated in the National Health Examination in South Korea between 2003 and 2004. National Health Insurance claims data after 16 years were used to determine the incidence of oral tumors and the related risk factors.

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A large thigh hibernoma in a 23-years-old man: Case report.

Int J Surg Case Rep

October 2024

Multidisciplinary Department of Medical-Surgical and Dental Specialties, Plastic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.

Introduction And Importance: Hibernomas are benign soft tissue tumors containing prominent brown adipocytes that resemble normal brown fat, they occur in a wide age range (from 2 to 75 years) and make up for about 1 % of all adipocytic tumors <2 % of benign fatty neoplasms. They have traditionally been regarded as benign tumors with no potential for malignancy; due to their similarity in clinical and radiographical presentation, they are often misdiagnosed as malignant tumors like liposarcomas. While these tumors are generally considered non-malignant, their distinctive characteristics and uncommon occurrence make them an intriguing subject for medical study.

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Leiomyomas and schwannomas are both types of rare benign soft tissue tumours. Leiomyomas are more commonly found in the lower limbs than in the upper extremities, while schwannomas are rare peripheral nerve sheath tumours that can occur in different anatomical regions. However, they rarely occur in the saphenous nerve.

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Introduction: Benign esophageal tumors are uncommon, accounting for approximately 2% of esophageal tumors. Esophageal schwannoma is a much rarer solid tumor with few cases reported in the literature. Open surgery is the surgical approach of choice for the treatment of esophageal tumors.

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Background: Dermatofibromas, also known as benign fibrous histiocytomas, are among the most common cutaneous soft-tissue lesions. Association of multiple dermatofibromas with some diseases was described and it has not been reported with Ehlers-Danlos syndrome before. We present a case with Ehlers-Danlos syndrome and multiple dermatofibromas.

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