8,472 results match your criteria: "Benign and Malignant Soft Tissue Tumors"

Osseous and cartilaginous soft tissue tumours are a heterogenous group of neoplasms characterised by the presence of an osseous or cartilaginous component. Mineralisation of the osseous or cartilaginous component is a common finding amongst these lesions, presenting as calcification/ossification on radiological imaging. This pictorial review examines the key imaging findings and characteristics of osseous and cartilaginous soft tissue tumours with a focus on the distinguishing features which can help the radiologist to differentiate benign and malignant lesions.

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Rationale And Objectives: Angioleiomyomas are benign perivascular tumors that originate from the tunica media of blood vessels. While frequently described in the head, neck, and uterus, angioleiomyomas can manifest in various regions throughout the body. The purpose of this study was to review the history and imaging features of angioleiomyomas of the trunk and extremities.

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Article Synopsis
  • * Imaging tests revealed a significant mass in the left bladder and a nonfunctional right kidney, leading to surgical removal of both the kidney and part of the bladder.
  • * The final diagnosis was a bladder glomus tumor, and the patient remains healthy with no signs of recurrence after 15 months, underscoring the need for urologists to consider glomus tumors in their diagnostic process.
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Scapulothoracic Disorders: Anatomy, Kinematics, Clinical Assessment, and Multimodality Imaging.

Radiographics

January 2025

From the Department of Musculoskeletal Radiology, Fleury Medicina E Saúde Higienópolis, Rua Mato Grosso 306, 1st Floor, Higienópolis, São Paulo, SP 01239-040, Brazil (I.A.N.d.C., M.C.F., L.N.M.d.S., F.F.A., D.V.C.G., M.A.C.N., J.B.G., A.G.O.F.); Department of Radiology, Mayo Clinic, Rochester, Minn (N.G.R.); and Department of Knee Surgery, Instituto Vita Ortopedia e Fisioterapia Higienópolis, São Paulo, Brazil (B.S.).

Shoulder and neck concerns are prevalent musculoskeletal issues prompting medical attention, often stemming from scapulothoracic disorders that can serve as both the cause and consequence of other shoulder abnormalities. Scapular dyskinesis, fractures, benign and malignant masses, and neuropathies are frequently overlooked yet can substantially affect shoulder pain and function, particularly in athletes. Scapulothoracic disorders may lead to and/or be worsened by common shoulder abnormalities including those of the rotator cuff, neighboring bursae, and the glenohumeral articulation and labrum.

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Myopericytoma is a rare benign smooth-muscle cell neoplasm of the subcutaneous soft tissues that is primarily found in young adults with a male predominance. We present the clinical, radiologic, and histopathologic features of a longstanding myopericytoma of the hand. We emphasize the features that help the radiologist and pathologist to accurately characterize this entity.

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Article Synopsis
  • The study aimed to analyze the epidemiology of patients with musculoskeletal tumors treated at a reference hospital from 2009 to 2022.
  • A total of 1978 patients were examined, revealing that 1477 (74.67%) had sarcomas, categorized into 446 bone tumors and 1,031 soft tissue tumors.
  • The findings highlighted the most common tumors, including enchondroma for benign bone tumors, osteosarcoma for malignant, lipomas for benign soft tissue tumors, and sarcomas of uncertain differentiation as the most frequent malignant soft tissue tumors.
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Synovial sarcoma under the lens: a case report.

Pan Afr Med J

December 2024

Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India.

Article Synopsis
  • A 56-year-old male patient presented with swelling above his right ankle, which was diagnosed as synovial sarcoma after imaging and histopathology.
  • Treatment involved surgical removal and chemotherapy; however, the 5-year survival rate is low, highlighting the challenge of accurately diagnosing this tumor due to its misleading characteristics.
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  • * A young man was found to have a right scrotal mass initially thought to be a solitary fibrous tumor but was later identified as a benign fibrous pseudotumor after thorough examination.
  • * This case underscores the need for detailed diagnostic methods, like advanced imaging and intraoperative evaluations, to prevent unnecessary surgeries and ensure correct treatment of these benign conditions.
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Pediatric soft tissue tumors.

Orthop Traumatol Surg Res

November 2024

Pediatric Orthopedics Department, Hôpital des enfants, CHU Purpan, Toulouse University, Toulouse, France.

The initial approach to soft tissue tumors in children and teenagers is everyone's responsibility. While the vast majority is benign, all practitioners dread missing a malignant lesion. The first step involves taking the patient's history and performing a clinical examination.

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Primary intraosseous carcinoma not otherwise specified (PIOC NOS) is a rare tumor assumed to arise from the epithelium, such as odontogenic cysts or benign tumors. Its clinical and imaging diagnoses are often challenging, especially in the early stages, as it mimics jaw cysts and benign tumors, and no specific findings have been identified. This report presents the case of a 66-year-old male patient with mandibular PIOC, highlighting the imaging findings over time.

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Atypical cellular neurothekeoma: a case report with a novel NF1 mutation.

Diagn Pathol

November 2024

Sistema Nacional de Investigación, Secretaria Nacional de Ciencia, Tecnología e Innovación, Panama City, Panama.

Atypical cellular neurothekeoma is a rare benign soft-tissue tumour that usually arises in the head and neck region, shoulder girdles, and proximal extremities, predominantly in young women. This dermal neoplasm is under-reported in the literature and is not uncommonly misdiagnosed as a malignant tumour due to its worrisome histologic characteristics. Currently, the diagnosis of cellular neurothekeoma relies on a panel of non-specific immunohistochemical markers and its etiopathogenesis is unknown.

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  • Elastofibroma dorsi is a rare, non-cancerous soft-tissue tumor commonly found in elderly women, usually causing no symptoms but potentially leading to discomfort and pain in the shoulder.
  • A case study of a 78-year-old man revealed an asymptomatic mass in the subscapular region, diagnosed and confirmed via MRI, and successfully removed through surgery with no complications.
  • The findings highlight the importance of imaging and histopathological analysis to differentiate elastofibroma dorsi from malignant conditions, along with a call for further research to understand its development mechanisms.
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  • Lipomatous tumors are the most common soft tissue neoplasms, and distinguishing between benign lipomas and more serious atypical lipomatous tumors requires accurate diagnostic methods, including MDM2/CDK4 immunostaining.
  • In a study involving 109 patients, only a small fraction of those diagnosed with atypical tumors tested positive for MDM2, indicating that traditional morphological diagnoses may be unreliable.
  • The study highlighted that certain clinical features, such as older patient age and larger tumor size, could help identify potential atypical tumors, even though the overall accuracy of the diagnostic methods assessed was not very high.
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Angiomyofibroblastoma is a benign, usually small neoplasm typically constituted by spindle-shaped and epithelioid cells in a vascularized, myxoid-fibrous stromal background. It is most often seen in the superficial genitalia of female patients of reproductive age. However, various clinical and histologic features have been reported, including tumors in male patients, malignant transformation, extragenital sites, huge sizes, and a prominent lipomatous pattern.

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  • Common benign subcutaneous masses include lipomas and epidermal cysts, which are the most frequently encountered in medical practice.* -
  • Other skin-related tumors can arise from structures like hair follicles, nerves, blood vessels, and sweat glands.* -
  • When ultrasound results are uncertain, radiologists must take steps to rule out the rare possibility of a cancerous sarcoma in the subcutaneous tissue.*
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Ganglioneuromas (GN) are benign, slow-growing, non-invasive, and well differentiated neoplasms of neuroblastic origin. We reported a 4 year old girl who presented with a left lateral slow growing cervical neck mass. After surgical excision the tumour was sent for histopathological examination which confirmed ganglioneuroma.

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Angiomyxolipoma of the Cheek: A Rare Oral Tumour.

Indian J Otolaryngol Head Neck Surg

December 2024

Dept of ENT and Head & Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.

Article Synopsis
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Prognostic factors in clear cell sarcoma: an analysis of soft tissue sarcoma in 43 cases.

J Cancer Res Clin Oncol

November 2024

Department of Medical Oncology and Sarcoma Center, West German Cancer Center, Medical School, University Duisburg-Essen, Essen, Germany.

Article Synopsis
  • Clear cell sarcoma (CCS) and its similar tumor, malignant gastrointestinal neuroectodermal tumor/sarcoma (GINET), often lead to local and distant relapses, with limited success from systemic treatments.
  • A study analyzed data from 43 patients, revealing a 5-year overall survival rate of 42%, with most tumors being EWSR1::ATF1-translocation-positive and showing a high rate of metastasis.
  • The findings highlighted that complete tumor resection significantly improves survival rates compared to incomplete resection, while systemic treatments and radiation were largely ineffective.
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  • Fibrous dysplasia (FD) is a nonheritable genetic condition that causes abnormal bone growth, leading to benign lesions that can sometimes become malignant, as exemplified in a case of a 61-year-old man with painful craniofacial FD.
  • The patient presented with a rapidly growing mass in the skull, which MRI revealed as an extensive dysplastic mass causing significant pressure on the brain; he underwent surgery to remove the mass.
  • Post-surgery pathology confirmed it as a high-grade undifferentiated pleomorphic sarcoma, leading to further treatment with chemotherapy, though the effectiveness of such treatment remains debated.
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