592 results match your criteria: "Benign Vulvar Lesions"
Vulvar Lactating Adenoma: A Rare Representation of Mammary-Like Anogenital Glands.
Int J Surg Pathol
December 2024
Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
Mammary-like anogenital glands are considered a normal constituent of the anogenital area. These glands can have epithelial components with eccrine or apocrine features. They often undergo transformation into mammary-like lesions, including lactational changes that occur during pregnancy and the breastfeeding period.
View Article and Find Full Text PDFPrevalence and impact of vulvar lesions diagnosed prior to vulvar squamous cell carcinoma: A population-based cohort study.
Gynecol Oncol
December 2024
Amsterdam UMC location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, the Netherlands; Cancer Centre Amsterdam, Imaging and Biomarkers, Amsterdam, the Netherlands. Electronic address:
Objective: To systematically explore vulvar pathology diagnosed prior to vulvar squamous cell carcinoma (VSCC), as well as the association with tumor characteristics, stage and survival outcome, with the aim of improving vulvar cancer prevention strategies.
Methods: VSCC diagnosed between 2005 and 2019 were identified from a population-based cohort provided by the Dutch Nationwide Pathology Databank. Pathology reports were reviewed to identify vulvar pathology diagnosed before primary VSCC.
Vulvar leiomyoma mimicking Bartholin's gland cyst: A case report.
Case Rep Womens Health
December 2024
Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Article Synopsis
Response to 1064 nm Nd:YAG LASER in treatment of vulvar Fordyce's Angiokeratoma: case report.
J Vasc Bras
October 2024
Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.
Article Synopsis
- - Fordyce's Angiokeratoma (AKF) is a benign vascular lesion found on the external genitalia of both males and females, with unknown prevalence and no known hereditary factors.
- - Diagnosis involves observing distinctive purple, bluish, black, or red papules on the affected areas, with most individuals experiencing no symptoms.
- - A case study of a 56-year-old woman with painful vulvar lesions revealed that treatment using the 1064 nm Nd:YAG LASER was effective, providing satisfactory results with minimal complications.
Vulval leiomyoma with acute postoperative delirium.
Prz Menopauzalny
June 2024
All India Institute of Medical Sciences, Bhubaneswar, India.
Article Synopsis
- - Leiomyomas are benign tumors, and while uterine versions are common, vulval leiomyomas are rare; this case involves a 41-year-old woman with a significant mass in her vulva and discomfort.
- - A preoperative ultrasound indicated a likely vulval leiomyoma, leading to surgical excision, but the patient experienced acute postoperative delirium shortly after the procedure.
- - After treatment for delirium, which included medication and electrolyte correction, the patient recovered well, and follow-up confirmed no recurrence, highlighting the need for awareness of postoperative complications in gynecological practices.
Invasive acantholytic anaplastic extramammary Paget disease: A previously unreported neoplasm in the vulva and review of the literature.
Gynecol Oncol Rep
December 2024
Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Providence, RI 02905, United States.
Article Synopsis
- The report discusses a unique case of invasive acantholytic anaplastic extramammary Paget disease (AAEMPD) found in an 87-year-old woman after multiple treatments for a persistent vulvar lesion.
- Microscopic examination revealed unusual features such as intraepidermal acantholysis and atypical cell growth, raising concerns of both EMPD and invasive carcinoma.
- Accurate diagnosis of AAEMPD is essential as it has different treatment strategies compared to other potential conditions, highlighting the need for careful assessment in clinical practice.
Vulvar Lymphangioma Arising in the Setting of May-Thurner Syndrome.
Case Rep Vasc Med
September 2024
Department of Pathology and Laboratory Medicine University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Article Synopsis
- The case report details a rare instance of vulvar lymphangioma in a 29-year-old woman with May-Thurner syndrome (MTS), a vascular condition causing left iliac vein obstruction.
- Lymphangioma, a benign lesion characterized by abnormal lymphatic channel dilation, is noted to be rare in the vulvar area.
- The report aims to highlight this unique association between vulvar lymphangioma and MTS, discussing the clinical aspects, causes, and potential connections between the two conditions.
Unusual Location of a Rare Tumor: Cutaneous Myxoma of the Scrotum.
Cureus
August 2024
General Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Article Synopsis
- Myxoma is a rare, non-cancerous tumor that can occur in various body parts, including the scrotum, and can be either cutaneous or intramuscular.
- Scrotal myxomas, though infrequent, can pose challenges in diagnosis due to their nonspecific clinical presentation, often requiring biopsy for confirmation.
- A case study of a 64-year-old male with a 20-year history of scrotal swelling revealed it to be a cutaneous myxoma after surgical excision and histopathological analysis.
A Rare Case of Vulval Leiomyoma.
Cureus
August 2024
Pathology, Jawaharlal Nehru Medical College, Wardha, IND.
Article Synopsis
- Vulval leiomyomas are very rare benign tumors made of smooth muscle, often difficult to diagnose due to their unusual location and similarity to other vulval conditions.
- A case study highlighted a 40-year-old woman with a painless mass on her vulva, which was diagnosed as a vulval leiomyoma after being biopsied.
- The typical treatment for vulval leiomyomas is surgical excision, which usually resolves the issue effectively.
Vulvar epidermal cyst in a 54-year-old virgin female: A very rare case report.
Int J Surg Case Rep
October 2024
University of Aleppo, Faculty of Medicine, Aleppo, Syria.
Article Synopsis
- Epidermal cysts, which may form due to female genital mutilation or trauma, are benign tumors that can appear in the vulvar or clitoral areas, especially in different age groups, warranting distinct diagnostic considerations.
- A 54-year-old woman experienced urinary retention due to a large vulvar epidermal cyst, which was successfully excised, alleviating her symptoms and restoring normal appearance.
- Accurate diagnosis and management of vulvar epidermoid cysts require thorough clinical evaluation and imaging, as they can cause significant issues when large, and surgical excision is typically recommended for symptomatic cases.
Clinicopathological Findings and Comprehensive Review of Buschke-Lowenstein Tumors Based on a Case Study.
J Pers Med
August 2024
Department 11, Discipline Plastic and Reconstructive Surgery, Bucharest Clinical Emergency Hospital, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania.
Article Synopsis
- The Buschke-Löwenstein tumor (BLT) is a rare, exophytic tumor linked to low-risk HPV strains, primarily appearing as a large, cauliflower-like growth in genital areas, which can be locally aggressive and has a notable recurrence rate.
- A 68-year-old patient with multiple health issues presented with a sizable tumor causing erectile dysfunction and urinary problems, which was successfully surgically excised with reconstruction.
- Histopathological analysis confirmed the diagnosis, and the patient's recovery underscores the importance of early diagnosis and surgical intervention to manage BLT and prevent complications like malignancy and recurrence.
MR imaging of benign vulvar lesions: a pictorial essay.
Abdom Radiol (NY)
August 2024
Mayo Clinic, Rochester, USA.
Article Synopsis
- - Benign vulvar lesions can be tricky to identify due to limited research on their imaging characteristics, despite many being diagnosed and treated clinically.
- - The rise in pelvic MRI use has led to more incidental findings of these lesions, helping clinicians better understand their anatomical context.
- - This essay reviews key MRI sequences for vulvar imaging and showcases various cystic and solid benign vulvar lesions to enhance radiologists' familiarity with their typical MRI appearances.
The Rarity in the Rarity: Presentation of Two Rare and Unusual Cases of Nodular Fasciitis and Proliferative Fasciitis.
Cureus
June 2024
Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Bari, ITA.
Article Synopsis
- Nodular fasciitis (NF) and proliferative fasciitis (PF) are benign tumors that can appear like cancer due to their fast growth and tissue characteristics, with NF mostly seen in young adults and PF in older adults.* * The article discusses two rare pediatric cases: a six-year-old with NF in the vulvar area and a ten-year-old with PF in the gluteal region, both showing rapid growth and unique tissue features.* * These cases emphasize the need for accurate diagnosis to prevent misdiagnosis and ensure proper treatment, especially since such conditions are rare in children and require more awareness among healthcare professionals.*
Leiomyoma of the Nipple: A Rare Entity at Rare Site.
Cureus
June 2024
Surgery, Maulana Azad Medical College, New Delhi, IND.
Article Synopsis
- Cutaneous leiomyomas are rare, benign smooth muscle tumors, with nipple leiomyomas being the least common and often found in middle-aged women.
- The case study describes a 40-year-old woman who had a 1cm growth on her right nipple for six months, which was excised and examined.
- Histopathological analysis confirmed a diagnosis of nipple leiomyoma, highlighting the importance of biopsy and immunohistochemistry for accurate diagnosis and effective patient management.
Unveiling the Truth: Fibroepithelial Polyp of the Vulva and Its Misdiagnosis as Cancer.
Cureus
June 2024
Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Article Synopsis
- * The case study involved a 45-year-old menopausal woman who had a progressively growing FEP in her vulva for seven years, measuring around 11x8x7 cm.
- * After surgical removal under anesthesia, the diagnosis of FEP was confirmed through histopathological examination, and the patient recovered well without any signs of recurrence.
A Rare Case of Hidradenoma Papilliferum of the Vulva.
J Obstet Gynaecol India
June 2024
Apollo Hospital, Navi Mumbai, India.
Article Synopsis
- - Hidradenoma Papilliferum is a rare but benign tumor found predominantly in the anogenital region of women aged 30-49, although it can also appear in atypical locations like the breast, ears, and eyelids, known as Ectopic Hidradenoma Papilliferum.
- - The tumor arises from apocrine or mammary-like glands and is characterized by a firm nodule with no connection to the skin's surface, often described as having a flesh to red color and a frond-like structure upon examination.
- - A case study highlights a 33-year-old woman who experienced a slow-growing nodule in her perineum for eight months; a biopsy confirmed the diagnosis
Molecular mechanisms of human papilloma virus related skin cancers: A review.
Medicine (Baltimore)
May 2024
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Article Synopsis
- HPV is a double-stranded DNA virus that often causes asymptomatic infections, with about 90% resolving on their own, but high-risk strains can lead to cancerous lesions in areas like the cervix and anus.
- The virus is known to contribute to various malignancies, particularly via its beta strains in skin cancers such as cutaneous squamous cell carcinoma, though its exact role in other skin cancers remains unclear.
- Recent studies suggest that HPV may also play a role in triggering other skin cancers, like basal cell carcinoma and melanoma, prompting a closer examination of its contributions to both benign and malignant skin lesions.
Proliferating inverted follicular keratosis of genital skin: Case series of a challenging variant.
J Cutan Pathol
August 2024
Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Article Synopsis
- Inverted follicular keratosis (IFK) is typically a harmless skin tumor, but some cases have presented similarly on genital skin with characteristics that could suggest squamous cell carcinoma (SCC).
- In a study of four young women with these genital tumors, researchers found distinct histopathological features indicating a non-invasive growth pattern, without signs of SCC, and confirmed the diagnosis through various tests.
- The findings led the authors to suggest calling these cases "proliferating IFK" to clarify that they are a variant of IFK and to prevent misdiagnosis as SCC.
Fibroadenoma of the vulva with pseudoangiomatous stromal hyperplasia: A common neoplasm in uncommon site.
J Cutan Pathol
August 2024
Department of Pathology, Cleveland Clinic, Cleveland, Ohio, USA.
Article Synopsis
- Mammary-type tissue in the vulva, first identified in 1872, is rarely documented and has historically been thought to be ectopic breast tissue from incomplete milk line regression, but new theories suggest it comes from normal vulvar glands.
- This tissue is hormonally sensitive and can develop both benign conditions like fibroadenoma and malignant changes.
- A case study of a 41-year-old woman revealed a cyst in the vulva, diagnosed as resembling a mammary fibroadenoma and highlighting the need for careful monitoring and excision due to the potential for malignancy and recurrence.
Human papillomavirus infection: Epidemiology, biology, host interactions, cancer development, prevention, and therapeutics.
Rev Med Virol
May 2024
Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.
Article Synopsis
- HPV is a common sexually transmitted infection caused by a DNA virus, which can lead to serious health issues, including various cancers associated with high-risk types like HPV-16 and HPV-18.
- Low-risk HPV types, such as HPV-6 and HPV-11, can cause benign conditions like genital warts, which, while not dangerous, can cause discomfort and distress.
- Prevention strategies include vaccination with effective HPV vaccines (such as Gardasil and Cervarix) and safe sexual practices, as HPV tests can be complicated due to the often asymptomatic nature of the infection.
Cellular angiofibroma arising from the rectocutaneous fistula in an adult: A case report.
World J Clin Cases
April 2024
Division of Colon and Rectal Surgery, Department of Surgery, Tri-Service General Hospital Songshan Branch, National Defense Medical Center, Taipei 105, Taiwan.
Article Synopsis
- Rectocutaneous fistulae develop from infections in anal glands and can lead to perineal masses, as seen in a rare case of cellular angiofibroma (CAF) associated with such a fistula.
- A 52-year-old male with a 2-year history of a painful perineal mass underwent imaging that revealed its connection to a rectocutaneous fistula, leading to surgical excision and diagnosis of CAF.
- The case illustrates that CT imaging is effective for diagnosing perineal lesions, and CAFs can be successfully removed even when linked to cutaneous fistulas.
A Case of Verruciform Xanthoma of Labia in a Child.
Clin Cosmet Investig Dermatol
April 2024
Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi, People's Republic of China.
Article Synopsis
- - The study presents a case of verruciform xanthoma (VX), a rare and benign skin condition, found in a 12-year-old female with vulvar lesions lasting over a decade without discomfort.
- - Examination revealed red, lobulated patches and specific histopathological features, including abnormal keratinization and inflammatory cell infiltration, leading to the diagnosis of VX.
- - Surgical treatment resulted in a successful outcome, highlighting an effective approach for managing this condition.
Fibroepithelial Polyp of the Vagina in Pregnancy: A Case Report.
J West Afr Coll Surg
February 2024
Department of Histopathology, University of Abuja Teaching Hospital, Abuja, Nigeria.
Article Synopsis
- - Fibroepithelial polyps of the vagina (FEPV) are benign growths that consist of a connective tissue core covered by squamous epithelium.
- - These polyps are considered rare, with only a handful of cases documented in medical literature.
- - Fibroepithelial stromal polyps can develop not only in the vagina but also in the vulva, cervix, and even in atypical locations like the breast and labia.
Pediatric Hemangiomas in the Female Genital Tract: A Literature Review.
Diseases
February 2024
Vulvar Pathology Study Center, 00161 Roma, Italy.
Article Synopsis
- - Hemangiomas are the most common benign soft tissue tumors in children, but those located in the genital area are rare, prompting this study to review literature on pediatric vulvovaginal hemangiomas for better diagnosis and treatment guidance.
- - The literature review from August 2009 to May 2023 showed that most hemangiomas are benign and often resolve on their own, but some can cause serious symptoms like heavy bleeding, necessitating advanced diagnostic methods like CT or MRI.
- - Existing treatments range from medical therapy to careful monitoring, with a need for more research on effective management, particularly for symptomatic cases; treatment should be tailored to individual circumstances and clinical expertise.