4,491 results match your criteria: "Benign Gastric Tumors"

Gastric duplication cysts (GDCs) are rare congenital anomalies, often identified during infancy or childhood. Although typically benign, there have been sporadic reports of malignant transformations, including adenocarcinoma and rare mixed tumors. Herein, we describe a rare case of mixed pancreatobiliary ductal adenocarcinoma and squamous cell carcinoma occurring within a GDC in a 54-year-old Korean woman with a history of melena and hematemesis.

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Objectives: This study aimed to investigate the causal effects of metabolic syndrome (MetS) components, including fasting blood glucose (FBG), HDL cholesterol (HDL-C), triglycerides (TG), waist circumference (WC), and hypertension, on the risks of chronic gastritis, benign gastric tumors, and gastric cancer using Mendelian randomization (MR) analyses.

Methods: Univariable two-sample Mendelian randomization (TSMR) and multivariable Mendelian randomization (MVMR) analyses were employed to evaluate the independent and combined effects of MetS components on gastric disorders. The primary MR method used was the random effects inverse variance weighted (IVW) approach.

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[Pancreatic cystic neoplasms: work-up and surveillance].

Praxis (Bern 1994)

November 2024

Abteilung für Gastroenterologie und Hepatologie, Stadtspital Zürich, Zürich

Whereas pancreatic masses are often difficult to detect with transabdominal ultrasound, cross-sectional imaging features high sensitivity for the pancreatic tumors. However, increasing availability of magnetic resonance imaging (MRI) has led to a surge in the detection of benign or precancerous pancreatic lesions. The medical history is characteristic only for two entities.

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Article Synopsis
  • - Mucosa-associated lymphoid tissue (MALT) lymphoma is a rare B-cell lymphoma that can affect various organs, and patients with Sjögren's syndrome (SjS) have significantly higher risks of developing it.
  • - A case study is presented of primary thymic MALT lymphoma found incidentally during routine chest imaging, alongside cystic lung disease, primarily observed in women with SjS.
  • - Imaging techniques revealed a large mass in the mediastinum and numerous pulmonary cysts; the diagnosis was confirmed via biopsy, and treatment improved lung function, emphasizing the link between SjS and MALT lymphoma's lung manifestations.
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Prognostic effect of immunohistochemically determined molecular subtypes in gastric cancer.

BMC Cancer

December 2024

Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, PO Box 340, Haartmaninkatu 4, Helsinki, HUS , FIN-00029, Finland.

Article Synopsis
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Prevalence of Neoplasms in Patients with Acromegaly-A Single-Center Polish Study.

J Clin Med

November 2024

Department and Clinic of Endocrinology and Internal Medicine, Wroclaw Medical University, Wybrzeże Pasteura 4, 50-367 Wroclaw, Poland.

Article Synopsis
  • Neoplasms are a leading cause of death in patients with acromegaly, which prompted this study to analyze the incidence and types of benign and malignant tumors in these patients.
  • Researchers examined the relationship between tumor prevalence, disease activity, diagnosis timing, and symptom onset, alongside hormone levels from the pituitary gland.
  • The study involved a review of records from 230 acromegaly patients in Poland, revealing significantly higher rates of both benign and malignant neoplasms in active cases compared to those who had been cured.
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Endoscopic submucosal dissection for the treatment of gastrointestinal neoplasia in a tertiary-care center in Mexico.

Cir Cir

November 2024

Departamento de Endoscopia Gastrointestinal, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Ciudad de México, México.

Objective: The aim of this study was to evaluate the experience of using endoscopic submucosal dissection (ESD), a technique considered as first-line of treatment, for the management of early neoplastic lesions (ENL), and subepithelial lesions (SEL) < 4 cms in size, in a tertiary-care, high-volume medical center in Mexico.

Method: Patients > 18 years-old, candidates to ESD with ENL and SMT, between January 2008 and October 2022 were included.

Results: ESD was performed in 246 patients (137 ENL and 109 SMT), 52.

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ILF2 protein is a promising serum biomarker for early detection of gastric cancer.

BMC Cancer

November 2024

Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, No 17, Yongwai Zheng Street, Nanchang, Jiangxi, 330006, China.

Background: Our previous small-sample study indicated that serum levels of interleukin enhancer binding factor 2 (ILF2) may have the potential for gastric cancer (GC) detection. The present study was conducted to further validate the diagnostic value of serum ILF2 protein for GC.

Methods: Serum specimens and clinical data were collected from patients with GC (n = 99) or benign gastric disease (BGD) (n = 49) and healthy controls (HC) (n = 51).

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Artificial intelligence efficiently predicts gastric lesions, infection and lymph node metastasis upon endoscopic images.

Chin J Cancer Res

October 2024

Department of General Surgery of Ruijin Hospital, Shanghai Institute of Digestive Surgery, and Shanghai Key Laboratory for Gastric Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Objective: Medical images have been increased rapidly in digital medicine era, presenting an opportunity for the intervention of artificial intelligence (AI). In order to explore the value of convolutional neural network (CNN) algorithms in endoscopic images, we developed an AI-assisted comprehensive analysis system for endoscopic images and explored its performance in clinical real scenarios.

Methods: A total of 6,270 white light endoscopic images from 516 cases were used to train 14 different CNN models.

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Gastric glomus tumor with uncertain malignant potential: case report of a rare cause of upper gastrointestinal bleeding.

World J Surg Oncol

November 2024

Department of Surgery, Albert Szent-Györgyi Health Center, University of Szeged, Semmelweis Street 8, Szeged, H-6725, Hungary.

Article Synopsis
  • Glomus tumors (GTs) are mostly benign neoplasms found in the upper gastrointestinal tract, making malignant cases exceptionally rare, which complicates diagnosis due to similarities with other tumors.
  • A 52-year-old male patient experienced fatigue and bleeding, leading to the discovery of a gastric GT after multiple examinations, with histopathology confirming it as a potentially malignant tumor.
  • The case highlights the need for detailed histopathological and molecular analysis for correct diagnosis and stresses the importance of surgical intervention and long-term monitoring for recurrence and malignancy risks.
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GLI1, CDK4, and MDM2 Co-Amplification Gastric Plexiform Fibromyxoma: A Case Report and Literature Review.

Genes Chromosomes Cancer

November 2024

Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Article Synopsis
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Background: Leiomyomas are benign smooth muscle tumors found at the gastroesophageal junction (GEJ) ( Mathew G, Osueni A, Carter YM. Esophageal Leiomyoma. StatPearls.

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Endoscopic "calabash" ligation and resection for small gastric mesenchymal tumors.

World J Gastrointest Endosc

October 2024

Department of Gastroenterology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, Shenzhen 518000, Guangdong Province, China.

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Background And Aim: The implementation of computer-aided detection (CAD) devices in esophagogastroduodenoscopy (EGD) could autonomously identify gastric precancerous lesions and neoplasms and reduce the miss rate of gastric neoplasms in prospective trials. However, there is still insufficient evidence of their use in real-life clinical practice.

Methods: A real-world, two-center study was conducted at Wenzhou Central Hospital (WCH) and Renmin Hospital of Wuhan University (RHWU).

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Article Synopsis
  • A submucosal heterotopic gastric gland (SHGG) contains benign gastric tissue in the submucosa, and diagnosing related neoplasms through biopsy is difficult.
  • A 74-year-old man had an upper stomach lesion found during endoscopy, leading to an endoscopic submucosal dissection (ESD) after a biopsy indicated a possible pyloric gland adenoma.
  • The pathology confirmed SHGG with focal dysplasia, and the patient had a smooth recovery with no recurrence over 5 years, showcasing ESD's effectiveness in treating SHGG-related neoplasms.
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Article Synopsis
  • Biliary amputation neuroma is a rare benign tumor that can occur after surgeries like cholecystectomy, causing challenges in distinguishing it from cholangiocarcinoma.
  • A case involving a 64-year-old man showed a bile duct tumor discovered incidentally, leading to multiple biopsies that initially did not rule out cancer, but surgery revealed it to be a benign amputation neuroma.
  • The findings highlight the importance of considering amputation neuromas in patients with prior bile duct surgeries and the usefulness of rapid intraoperative histological examination to prevent unnecessary extensive surgeries.
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Article Synopsis
  • This study aimed to understand the relationship between Traditional Chinese Medicine syndromes and the progression of gastric diseases related to H. pylori infection by merging TCM concepts with modern molecular biology and histopathology methods.
  • It involved 203 participants, identifying key microRNA expressions (miR-499 and miR-149) and their link to various gastric conditions, revealing that miR-149 C allele is associated with lower gastric atrophy risk, while miR-499 levels correlate with higher cancer risk.
  • The findings suggest that H. pylori infection exacerbates the progression of gastric lesions, particularly in patients with specific TCM syndromes, indicating a need for targeted treatment approaches in these populations.
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