3,301 results match your criteria: "Benign Cardiac Tumors"

Cardiac myxoma with high standardized uptake value of FDG-PET-CT in the right ventricular outflow tract.

Gen Thorac Cardiovasc Surg Cases

December 2024

Department of Cardiovascular Surgery, Teikyo University Hospital, 2-21-1 Kaga, Itabashi-Ku, Tokyo, 173-8606, Japan.

Background: Cardiac myxoma rarely occurs in the right ventricle, and as is a benign disease, it rarely shows high positivity on 18F fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT).

Case Presentation: We present herein the case of a 77-year-old woman who was found to have a heart murmur during a routine health checkup. Further examination revealed a 27-mm tumor in the right ventricular outflow tract (RVOT) and moderate aortic valve stenosis.

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Background: Primary cardiac tumors (PCT), such as myxoma, are rare and predominantly benign. Angiofibroma tumors are an extremely rare subtype of PCT, reported in less than ten cases. In this study, we presented a mixed tumor of myxoma and angiofibroma for the first time in the human heart.

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Primary cardiac tumors are rare, most of them being benign. Most malignant cardiac tumors are sarcomas, with the most important therapeutic option being surgery, along with perioperative chemo- and radiotherapy. Here, we present a case of a 67-year-old female patient with no prior medical condition, who presented with primary cardiac sarcoma and extensive tumor growth in the pulmonary artery.

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Cardiac myxoma in its morphology is a typical benign tumor, meanwhile, the fact of its localization in the heart chamber, directly in the constant blood flow, largely determines the clinical behavior of this neoplasm, which is often manifested by the development of characteristics that formally determine the aggressive and even malignant nature of the course. Accordingly, the malignancy of cardiac myxoma is determined more by its clinical behavior (recurrence, multifocality of the lesion, the presence of mechanisms of spread similar to metastasis) rather than by its histological picture. In the structure of primary benign tumors of the heart, myxoma occupies a dominant position and its incidence is up to 85%.

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Phaeochromocytomas are rare catecholamine-secreting tumours, usually benign, originating from chromaffin cells of the adrenal glands. Their typical presentation includes the triad of headaches, sweating and tachycardia due to excessive catecholamine release. However, many patients do not exhibit all three symptoms, making diagnosis challenging.

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Introduction: Cardiac myxomas are the most common benign neoplasms of the heart, mainly located in the left atrium. The preferred treatment is the resection of the myxoma. This method not only prevents complications but also has a low recurrence rate.

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Article Synopsis
  • Uterine leiomyomas can sometimes lead to serious conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE), even in patients with no known risk factors.
  • A 38-year-old woman experienced leg swelling, pain, and breathing difficulties and was diagnosed with DVT and PE, which were confirmed through imaging.
  • The treatment involved mechanical thrombectomy and hysterectomy, resulting in a full recovery with no recurrence of thromboembolic events after 11 months.
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  • Cardiac teratomas are rare, making up less than 1% of adult heart tumors, with the intracardiac variety being even more uncommon, posing diagnosis and treatment challenges.* -
  • A 50-year-old man diagnosed with a right ventricular teratoma was successfully treated; imaging techniques revealed a significant mass, and surgery led to a good recovery with no recurrence in 2 years.* -
  • Intracardiac teratomas are mostly benign tumors, primarily affecting the right ventricle, and effective treatment through surgical removal often results in a positive outcome.*
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Article Synopsis
  • * A case study described a 39-year-old man who experienced severe chest pain due to a heart attack linked to a PFE found on imaging, which showed a mass near his aortic valve.
  • * The patient successfully underwent surgery to remove the tumor, and the case underscores the need for advanced imaging techniques to identify these rare tumors, as well as the urgency of surgery when they cause symptoms.
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Article Synopsis
  • * Surgical removal is often required to prevent issues like embolization; these tumors can appear randomly or as part of genetic conditions such as the Carney complex.
  • * A case of a 31-year-old man with a right atrial myxoma is discussed; after surgery, he later developed acute pericarditis linked to COVID-19, possibly due to his prior heart surgery.
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Reply: Type and dimensions can predict ventricular arrhythmias and cardiac death in primary benign cardiac tumors in children.

Int J Cardiol

February 2025

Pediatric Cardiology and Cardiac Arrhythmias and Syncope Unit, Bambino Gesù Children's Hospital, IRCSS, 00146 Rome, Italy; European Reference Network for Low Prevalence and Rare Disease of the Heart- ERN Guard Heart, Italy. Electronic address:

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Article Synopsis
  • Primary cardiac tumors (PCTs) like myxomas and lipomas are rare, with lipomas being soft fat masses that can lead to diagnostic challenges.
  • Lipomatous hypertrophy of the atrial septum (LHAS) is a benign condition linked to aging and obesity, distinct from true cardiac lipomas.
  • A case of a true atrial septal lipoma discovered during heart dissection is detailed, highlighting its potential effects on heart function and contributing to the scarce literature on benign primary cardiac tumors.
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Article Synopsis
  • * In a case study, a pregnant patient faced discomfort due to a large fibroid, prompting a multidisciplinary team to manage her symptoms and ultimately deliver her baby via cesarean section at 35 weeks.
  • * After delivery, she underwent a successful surgery to remove the fibroid, which weighed 7 kg; a cesarean myomectomy wasn't performed during pregnancy due to the fibroid's risky location near major blood vessels.
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A Rare Case of Solitary Cardiac Myofibroma in an Infant.

World J Pediatr Congenit Heart Surg

January 2025

Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

Article Synopsis
  • Solitary myofibromas are rare, benign tumors mostly found in the head and neck, but this report focuses on an unusual case of a solitary cardiac myofibroma in an infant.
  • A two-month-old was diagnosed with a 2×1 cm mass on the mitral papillary muscle, leading to severe heart regurgitation; imaging techniques were used to assess the mass.
  • Surgical removal was performed and the patient recovered well, with follow-up showing no recurrence of the tumor and minor regurgitation issues.
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Article Synopsis
  • Cardiac hemangioma is a rare, benign tumor that can be asymptomatic or cause symptoms depending on its location and interaction with nearby structures.
  • A case study describes a 79-year-old patient diagnosed with right cardiac hemangioma after experiencing severe symptoms like fluid buildup and heart failure.
  • The tumor was successfully removed using cardiopulmonary bypass, leading to a favorable outcome after 12 months, highlighting its unusual size and location near the tricuspid valve.
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Thirty-five years of single-center experience in cardiac myxoma surgery and related postoperative complications.

Kardiochir Torakochirurgia Pol

September 2024

Department of Cardiovascular Surgery and Transplantology, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.

Article Synopsis
  • * Researchers analyzed data from 166 patients, mostly middle-aged women, noting that the majority underwent median sternotomy, with few requiring alternative methods.
  • * The procedure showed a low complication rate (12%) and a mortality rate of 3.6%, with no significant differences related to gender, indicating myxoma surgery is generally safe compared to other heart surgeries.
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Article Synopsis
  • * While often asymptomatic, IHHs can lead to serious complications in infants, such as heart issues, low thyroid hormone levels, and stunted growth if not treated promptly.
  • * The case study discusses a boy with both small skin hemangiomas and multiple liver tumors, emphasizing the diverse locations and patterns of these vascular lesions in the body.
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Article Synopsis
  • - Papillary fibroelastoma is a rare benign tumor of the aortic valve that may cause obstruction, embolization, or be asymptomatic; diagnosis mainly relies on echocardiography.
  • - Transthoracic echocardiography may miss small tumors due to size sensitivity, which can lead to missed diagnoses.
  • - A case study showed a tumor detected by intraoperative transesophageal echocardiography, leading to successful surgical resection while preserving the aortic valve, emphasizing the importance of intraoperative imaging for accurate diagnosis.
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Article Synopsis
  • The study evaluated the outcomes of cardiac tumor resections using minimally invasive endoscopic (ENDO) techniques versus conventional sternotomy (CS) methods over 13 years with 34 patients involved.
  • The ENDO group consisted of younger and more female patients, and both groups had similar rates of in-hospital mortality and strokes, with no significant differences in recovery times.
  • Ultimately, both surgical approaches proved to be safe and effective, with no tumor recurrences in either group during follow-up.
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Effects of patient pleural effusion fluids on the BBSome components expression of human benign mesothelial cells.

Am J Physiol Lung Cell Mol Physiol

January 2025

Department of Physiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, Larissa, Greece.

Article Synopsis
  • The study investigates how benign mesothelial cells respond to different types of pleural effusion fluids (PF) and focuses on the role of the BBSome in this process.
  • Benign human mesothelial cells were exposed to PF from various conditions (mesothelioma, breast cancer, hemothorax, congestive heart failure) and changes in gene expression were measured using PCR to assess cell response.
  • Results show that BBSome gene expression changes more significantly in 2D cultures compared to 3D, and that inducing disturbances in the Primary Cilium affects cell migration in both culture formats when exposed to PF.
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Article Synopsis
  • MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in regulating gene expression and may serve as biomarkers for various diseases through their presence in plasma.
  • The study analyzed 2083 plasma circulating miRNAs from participants in the Rotterdam Study, uncovering 3292 associations between SNPs and miRNAs, with a significant portion confirmed in further studies.
  • Findings suggest that specific miRNAs can influence a range of clinical conditions, with miR-1908-5p showing a protective effect against benign colon neoplasm, highlighting the potential for miRNA-targeted therapies in medicine.
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Article Synopsis
  • Papillary fibroelastoma is a rare but potentially dangerous benign heart tumor that can lead to serious complications like ischemic strokes and sudden death if not surgically removed urgently.
  • A case study of a 34-year-old man who experienced an ischemic stroke revealed a mobile tumor located near the mitral valve, which was successfully excised via surgery with no complications.
  • The surgery confirmed the diagnosis of papillary fibroelastoma and the patient's condition improved, highlighting the importance of surgical intervention to prevent future embolic events.
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