Biocontrol of virulent Listeria monocytogenes using green carboxylated cellulose nanocrystals-silver nano-biohybrids.

L. monocytogenes is a Gram-positive bacterial pathogen, known to cause food poisoning and systemic disease, specifically listeriosis. This species has shown resistance to many commonly used antibiotics, making the search for new alternative therapies is a pressing matter.

Protective effects of quercetin against tongue injury and oxidative stress triggered by irinotecan: a histopathological, biochemical and molecular study.

Introduction: About 80% of patients receiving chemotherapeutics suffer from side effects related to the gastrointestinal tract. Irinotecan (CPT-11) is a chemotherapeutic agent usually used in treating solid tumors. Quercetin (QRT), a bioflavonoid, is an antioxidant and scavenger reactive oxygen species scavenger.

Carbohydrate-mediated interactions between chloroviruses and the immune system.

Understanding the molecular mechanisms which drive and modulate host-pathogen interactions are essential when designing effective therapeutic and diagnostic approaches aimed at controlling infectious diseases. Certain large and giant viruses have recently been discovered as components of the human virome, yet little is known about their interactions with the host immune system. We have dissected the role of viral N-linked glycans during the interaction between the glycoproteins from six chloroviruses (belonging to three chlorovirus classes: NC64A, SAG, and Osy viruses) and the representative carbohydrate-binding receptors of the innate immune system.

Avian pathogenic Escherichia coli and ostriches: a deep dive into pathological and microbiological investigation.

Objective: A comprehensive research was conducted to investigate the incidence of avian pathogenic Escherichia coli (APEC) in ostrich farms in Egypt.

Methods: The study involved seven farms with bird ages ranging from 1 to 12 weeks and capacities of 2,000 to 5,000 birds per farm. 175 tissue specimens were collected from different organs (liver, spleen, heart, lung, kidney, intestine, and meat).

Innovative CO-NBs-assisted ultrasonication for the phytochemical extraction of peanut (Arachis hypoga) shells: Synthesis and characterization of CO-nanobubbles.

This study was designed to obtain the maximum extraction yield of peanut shell (PS) polyphenols using a novel carbon dioxide nanobubbles (CO-NBs) assisted ultrasonic extraction method. CO-NBs were generated in distilled water with a self-developed high-pressure nano-jet homogenization method and characterized by size, zeta potential and transmission electron microscopy (TEM). The obtained nanobubble's mean size and zeta potential were 229.

Could hawthorn have a cardioprotective impact against obesity-induced cardiac injury in rats via antioxidant, hypolipidemic, anti-inflammatory, antiapoptotic, and antifibrotic properties?

Obesity is a major worldwide health problem affecting one billion people. The purported cardioprotective benefits of hawthorn against cardiovascular diseases (CVDs) are controversial and may be attributed to its antioxidant and anti-inflammatory properties. The current study explored the underlying protective mechanisms of hawthorn berry extract (HBE) against obesity-induced cardiac injury in rats.

Effect of Tui-Na versus positional release techniques on pregnancy-related low back pain in the third-trimester: A randomized comparative trial.

Background: Researchers are prioritizing the development of an effective treatment approach for third-trimester pregnancy-related low back pain (LBP), a prevalent and costly disorder. Therefore, this study aimed to examine the effects of Tui-Na (TN) versus positional release techniques (PRT) on third trimester pregnancy-related LBP.

Methods: Fifty pregnant women in their third trimester with low back pain were randomly assigned to 1 of 2 groups for 4 weeks of prescribed treatment (TN or PRT).

Anorectal Remodeling in the Transitional Zone with Increased Expression of LGR5, SOX9, SOX2, and Keratin 13 and 5 in a Dextran Sodium Sulfate-Induced Mouse Model of Ulcerative Colitis.

Although hyperplasia of the anorectal transitional zone (TZ) has been reported in mouse models of ulcerative colitis, the mechanisms underlying this phenomenon are not fully understood. We characterized keratin subtypes and examined the expression of stem cell markers in the TZ. Dextran sodium sulfate-treated mice showed abnormal repair of the anorectal region, which consisted of mixed hyperplastic TZ and regenerating crypts.

The role of the hypothalamus-gut microbiota in the pathogenesis of periparturient fatty liver disease in dairy cows.

During the periparturient period, dairy cows experience negative energy balance due to reduced feed intake, leading to adipose tissue breakdown, liver damage, and fat accumulation. This study examined the gut-liver-brain axis to explore the link between fatty liver disease, changes in hypothalamic appetite-related neurons, and microbiome shifts in dairy cows. Thirty cows were monitored, with daily DMI recordings and blood sampling.

Safety of erythrocyte transfusion over a short period in pediatric patients assessed using cardiac deformation imaging.

Erythrocyte transfusion is a time-consuming process for both health care personnel and patients. This research is aimed at assessing the safety of erythrocyte transfusion over a short period of time in pediatric patients using innovative echocardiographic parameters, such as tissue Doppler imaging and 2D speckle-tracking echocardiography. Twenty pediatric patients with chronic hemolytic anemia were included in the study.

On stratified single-valued soft topogenous structures.

This paper presents novel concepts including stratified single-valued neutrosophic soft topogenous (), stratified single-valued neutrosophic soft filter (), stratified single-valued neutrosophic soft quasi uniformity () and stratified single-valued neutrosophic soft quasi proximity (). Additionally, we present the idea of single-valued neutrosophic soft topogenous structures, formed by integrating svns-topogenous with svns-filter, and discuss their properties. Furthermore, we explore the connections between these single-valued neutrosophic soft topological structures and their corresponding stratifications.

New solutions of time-fractional cancer tumor models using modified He-Laplace algorithm.

Cancer develops through cells when mutations build up in different genes that control cell proliferation. To treat these abnormal cells and minimize their growth, various cancer tumor samples have been modeled and analyzed in literature. The current study is focused on the investigation of more generalized cancer tumor model in fractional environment, where net killing rate is taken into account in different domains.

Systemic inflammatory indices as a non-invasive grading modality for endometriosis: a comparative study versus exploratory laparoscopy.

Objective: Included evaluation of the possibility of using the systemic inflammatory indices for preoperative screening for the presence and severity of endometriosis (EM) in comparison to the findings of the exploratory laparoscopy.

Methods: 88 women with clinical manifestations suggestive of EM were evaluated clinically and by US and gave blood samples for estimation of serum cancer antigen-125 (CA125), platelet and total and differential leucocytic counts for calculation of inflammatory indices; the Systemic Immune-Inflammation index, the Systemic Inflammation Response Index (SIRI), the Neutrophil-Lymphocyte ratio (NLR), the Neutrophil-Monocyte ratio, the Neutrophil-Platelet ratio and the Platelet-Lymphocyte ratio. Then, patients were prepared to undergo laparoscopy for diagnosis and staging.

A reinforcement learning approach for reducing traffic congestion using deep Q learning.

Nowadays, traffic congestion is a significant issue globally. The vehicle quantity has grown dramatically, while road and transportation infrastructure capacities have yet to expand proportionally to handle the additional traffic effectively. Road congestion and traffic-related pollution have increased, which is detrimental to society and public health.

Synthesis of eco-friendly lipid-magnetite nanocomposite encapsulated Poinciana extract as promising insecticide against Culex pipiens.

Mosquito-borne diseases represent a growing health challenge over time. Nanostructured lipid carriers (NLCs) are the second generation of solid lipid nanoparticles (SLNs), and they continue to attract significant interest as potential diagnostic and therapeutic tools in disease inhibition and insect control. Activated ingredients presented in the Poinciana leaves were extracted and GC-MS data indicated an increased abundance of terpenes, flavonoids, and phenolic substances.

Rhazes' insights on abortion and abortogenic drugs in relation to modern concepts.

Abortion remains one of the most prevalent complications of pregnancy, contributing significantly to maternal mortality and presenting a substantial public health challenge. This study aimed to explore Rhazes' perspective on abortion and abortifacient medicinal plants he mentioned in Kitāb al-Ḥāwī fī al-Ṭibb. A detailed analysis of his seminal work, Kitāb al-Ḥāwī fī al-Ṭibb, was conducted.

Correction: Reinvestigation of Passerini and Ugi scaffolds as multistep apoptotic inducers dual modulation of caspase 3/7 and P53-MDM2 signaling for halting breast cancer.

[This corrects the article DOI: 10.1039/D3RA04029A.].

The Preventive Effect of Zinc Sulfate against Olanzapine-Induced Testicular Toxicity in Male Rats.

Male infertility is a complex and multifactorial clinical condition affecting a large population attributed to several factors, including perturbation in oxidative stress and the level of essential trace elements. Oxidative stress exerts multiple issues related to reproductive health, including male infertility, decreased sperm motility, sperm DNA damage, and an increased susceptibility to genetic disorders. Besides chemical toxins and food allergens in junk food items, many drugs can also lead to male infertility.

FERDCNN: an efficient method for facial expression recognition through deep convolutional neural networks.

Facial expression recognition (FER) has caught the research community's attention recently because it can affect many real-life applications. Multiple studies have focused on automatic FER, most of which use a machine learning methodology, FER has continued to be a difficult and exciting issue in computer vision. Deep learning has recently drawn increased attention as a solution to several practical issues, including facial expression recognition.

A comparative analysis of variants of machine learning and time series models in predicting women's participation in the labor force.

Labor force participation of Egyptian women has been a chronic economic problem in Egypt. Despite the improvement in the human capital front, whether on the education or health indicators, female labor force participation remains persistently low. This study proposes a hybrid machine-learning model that integrates principal component analysis (PCA) for feature extraction with various machine learning and time-series models to predict women's employment in times of crisis.

Using supervised machine learning algorithms to predict bovine leukemia virus seropositivity in dairy cattle in Florida: A 10-year retrospective study.

Supervised machine-learning (SML) algorithms are potentially powerful tools that may be used for screening cows for infectious diseases such as bovine leukemia virus (BLV) infection. Here, we compared six different SML algorithms to identify the most important risk factors for predicting BLV seropositivity in dairy cattle in Florida. We used a dataset of 1279 dairy blood sample records from the Bronson Animal Disease Diagnostic Laboratory that were submitted for BLV antibody testing from 2012 to 2022.

Local control and patient survival after stereotactic radiosurgery for esophageal cancer brain metastases: an international multicenter analysis.

Objective: This study aimed to evaluate local control (LC) of tumors, patient overall survival (OS), and the safety of stereotactic radiosurgery (SRS) for esophageal cancer brain metastases (EBMs).

Methods: This retrospective cohort study used data from 15 International Radiosurgery Research Foundation facilities encompassing 67 patients with 185 EBMs managed using SRS between January 2000 and May 2022. The median patient age was 63 years, with a male predominance (92.