Fansidar drug induces cytotoxicity in some vital tissues in a rat model: combination defensive effect of selenium and zinc capsules.

Aim: Fansidar (FAN) is widely used as an antimalarial drug, but it may cause hepatoxicity, nephrotoxicity, and neurotoxicity. Hence, the study examines the cytoprotection of selenium (Se) and zinc (Zn) tablets against FAN induced toxicity.

Method: Group I was given distilled water.

Estimation of radon excess lung cancer near some dumpsites in, Lagos, Nigeria.

Generally, in Nigeria dumpsites are open and elevate the pollution by increasing the total environment contamination level. This affects not only the site of dumpsites but also the surrounding buildings and area. In the present work, indoor radon activity concentration is tested inside some buildings in the vicinity of dumpsites in Lagos, Nigeria.

Experimental Investigation and Time Effect on the Anticorrosion and Microstructural Properties of Zinc Flake Nickel-Phosphorus Coating Electrodeposited on Mild Steel.

In this work, the potential of ZnSO·7HO in NiP sulphate electrolyte deposited on mild steel under constant optimum pH of 5, current density of 1 A/cm, stirring rate of 200 rpm, and varying time parameter between 10, 15, 20, and 25 min were studied using the electrodeposition method. The microstructure properties and corrosion resistance characteristics were analyzed using a scanning electron microscope enhanced with an energy-dispersive spectroscope and potentiodynamic polarization apparatus, respectively. The codeposited was subjected to different media test rig of 0.

Alterations in the biochemical indices in Wistar rats exposed to an overdose of codeine and dextromethorphan.

Objective: This study investigates the impact of repeated oral exposure to two cough syrups containing codeine and dextromethorphan (DXM) on male Wistar rats.

Methods: We divided 35 rats into seven groups of five rats each. Group A was given 0.

Attenuation of potassium dichromate and sodium arsenite toxicities by methanol extract of in mice.

Objectives: Exposure to arsenic and hexavalent chromium is a major public health concern especially in the developing part of the world and there is paucity of information on reliable treatment modalilities. It is in this regard that this study evaluates the efficacy of methanol leaf extract of (MRV) when used as pretreatment agent against potassium dichromate (KCrO) and sodium arsenite (NaAsO) exposure.

Methods: Swiss albino mice between 7 and 10 weeks old were divided into eight cohorts of five animals each.

Discovery of new promising USP14 inhibitors: computational evaluation of the thumb-palm pocket.

Ubiquitin-specific protease 14 (USP14) is a member of the deubiquitinating enzymes (DUBs) involved in disrupting the ubiquitin-proteasome regulation system, responsible for the degradation of impaired and misfolded proteins, which is an essential mechanism in eukaryotic cells. The involvement of USP14 in cancer progression and neurodegenerative disorders has been reported. Thereof USP14 is a prime therapeutic target; hence, designing efficacious inhibitors against USP14 is central in curbing these conditions.

Mezoneuron benthamianum inhibits cell adherence, hyphae formation, and phospholipase production in Candida albicans.

The aim of this study was to evaluate the phytochemical constituents, antioxidant, antifungal, and anti-virulence activities of traditionally used Mezoneuron benthamianum leaves. Extracts were prepared using acetone and methanol, and the preliminary phytochemical screening was performed. The antioxidant activity was studied using the DPPH method.

Genetic studies of extra-early provitamin-A maize inbred lines and their hybrids in multiple environments.

Vitamin A deficiency, drought, low soil nitrogen (low-N), and parasitism of maize ( L.) cause malnutrition and food insecurity in sub-Saharan Africa. The objectives of this study were to determine combining abilities of extra-early provitamin A (PVA) lines, classify them into heterotic groups (HGs), identify testers, and determine yield stability of hybrids under contrasting environments in two trials.

Determination of radon exhalation rates from soil around buildings in Lagos environments using passive measurement technique.

Purpose: In this study, measurements of radon concentrations and estimation of exhalation rates were carried out in soil around buildings within Lagos State in order to determine the contribution to indoor radon concentrations from the soil, and determine the influence of soil moisture on the exhalation rates.

Methods: Fifty-four samples were collected randomly with 27 measured as wet samples and 27 dried before measurements so as to account for the moisture content. Passive measurement method, using cover cup technique with solid state nuclear track detectors, CR-39, was employed.

Impact of gas flaring on surface and underground water: a case study of Anieze and Okwuibome areas of Delta State, Nigeria.

Gas flaring is a major activity in oil exploration processes in Nigeria with concerns on its effects on the oil communities. This study investigated the contribution of flare gases to pollution burden of Anieze and Okwuibome communities. Water samples were displayed at 10-m, 50-m, and 100-m locations from gas-flaring stations, and control samples were taken in another location.

Social capital and its effect on business performance in the Nigeria informal sector.

This study was aimed at investigating the effect of internal and external social capital on the financial and non-financial performance of businesses in the Nigerian informal sector. The study further investigated the controlling role of firm age. A cross-sectional survey of 650 informal business owners in the Ikeja region of Lagos state, Nigeria was carried out.

Concentration and Distribution of Organochlorine Pesticides in Sediments of the Niger River, Nigeria.

Background: Pollution in aquatic ecosystems is a serious environmental concern. There is a great need for constant assessment and monitoring of hazardous substances, particularly in aquatic environments in developing countries, as rivers are media with easy trans-boundary transport of chemical substances.

Objectives: The present study assessed the occurrence and distribution of organochlorine pesticides (OCPs) in the sediments of the Niger River, Nigeria.

Initial Inventory of Plastics Imports in Nigeria as a Basis for More Sustainable Management Policies.

Background: Plastic is a waste stream with recycling and recovery potential. However, the recycling rates for plastic in African countries are low. Furthermore, use and production of virgin plastics are increasing.

Polychlorinated Biphenyls in Brackish Water Fish in the River Niger, Nigeria.

Background: Anthropogenic polychlorinated biphenyls (PCBs) in aquatic environments poses human and ecological health risks in Nigeria.

Objectives: This study determined the concentrations of PCBs in brackish water fish in the River Niger to assess the contamination status of fish consumed by the local population.

Methods: The sampled fish species included Drepane africana, Mochokus niloticus, Chrysichthys nigrodigitatus, Pristipoma jubelini, Vomer septapinis, Pseudotolithus senegalensis, Mugil cephalus, Pseudotolithus elongatus, Sphyraena piscatorum and Lutjanus goreensis, purchased from landing sites.

Toxicokinetics and Biliary Excretion of N-Nitrosodiethylamine in Rat Supplemented with Low and High Dietary Proteins.

Although biliary excretion is one of the biological elimination processes for foreign compounds, intake of high-protein diets was hypothesized to enhance their detoxification rates. Hence, this study investigates the effect of differential dietary protein intake on toxicokinetics and biliary excretion in rats following exposure to N-nitrosodiethylamine (NDEA) and aflatoxin B1 (AFB1). The animals were divided into five groups.

Board meeting frequency and firm performance: examining the nexus in Nigerian deposit money banks.

The main aim of this study is to examine the impact of board meeting frequency on firm performance of deposit money banks in Nigeria. Data used for the study were spawned from annual reports of the deposit money banks listed on Nigeria stock exchange (NSE) market. We employed a panel regression to test the significant association amid variables.

Survey dataset on occupants׳ satisfaction with housing and life in public residential estates in Ogun State, Nigeria.

This article describes the data associated with the research paper entitled "Subjective life satisfaction in public housing in urban areas of Ogun State" by Ibem and Amole (2013). A multistage sampling technique and questionnaire were used to extract data from occupants in 517 dwelling units in ten selected government mass housing schemes located in five urban centers in Ogun State, Nigeria. The dataset has 57 different variables describing households' demographics, dwelling units' features, supply of basic services, and neighbourhood environment in the residential estates.

Datasets for board meeting frequency and financial performance of Nigerian deposit money banks.

This article provides data on the impact of board meeting frequency and financial performance of deposit money banks in Nigeria. We obtained the dataset from Nigeria stock exchange (NSE) database. The time frame used for this work is 2010-2016.

Levels of Organochlorine Pesticides in Brackish Water Fish from Niger River, Nigeria.

Investigation of the levels of organochlorine pesticides (OCPs) in fish samples was carried out to assess the contamination status of Niger River. Ten different brackish water species of fish (6 samples for each, making a total of 60) were purchased from landing sites at the Delta area of Niger River. These were , and .

The Integrative Conjugative Element (ICEclc) of JB2.

Integrative conjugative elements (ICE) are a diverse group of chromosomally integrated, self-transmissible mobile genetic elements (MGE) that are active in shaping the functions of bacteria and bacterial communities. Each type of ICE carries a characteristic set of core genes encoding functions essential for maintenance and self-transmission, and cargo genes that endow on hosts phenotypes beneficial for niche adaptation. An important area to which ICE can contribute beneficial functions is the biodegradation of xenobiotic compounds.

Survey dataset on professional's perception on site supervision and project performance.

Effective site supervision plays an important role in construction project delivery. This situates site supervisors in taking the responsibilities of coordinating and controlling all physical aspects of the day-to-day task in construction projects. A cross-sectional design approach was adopted by administering a well-structured questionnaire to selected built environment professionals.

Peak particle velocity data acquisition for monitoring blast induced earthquakes in quarry sites.

The peak particle velocity datasets recorded during quarry blasts in the neighborhood villages and towns in Ibadan and Abeokuta were processed and analyzed in order to recommend a safe blast design for each of the quarries. The minimum peak particle velocity of 48.27 mm/s was recorded near the foundation of the nearest residence at the shot to monitored distance of 500 m.

Data exploration of social client relationship management (CRM 2.0) adoption in the Nigerian construction business.

Integrating social client relationship management (CRM 2.0) in the built environment can enhance the relationship between construction organizations and client towards sustaining a long and lasting collaboration. The data exploration analyzed the e-readiness of contracting and consulting construction firms in the uptake of CRM 2.

Data on customer perceptions on the role of celebrity endorsement on brand preference.

This research presents data on the effect of celebrity endorsement on consumers' brand preference. Copies of structured questionnaire were administered to 384 customers of telecommunication industry. Using descriptive, correlation and regression statistical analysis, the data revealed that celebrity image has an effect on consumer brand loyalty, celebrity trustworthiness has an influence on consumer brand association.

Workforce diversity among public healthcare workers in Nigeria: Implications on job satisfaction and organisational commitment.

The aim of this research was to present a data article that identify the relationship between workforce diversity, job satisfaction and employee commitment among public healthcare workers in Nigeria. Copies of structured questionnaire were administered to 133 public healthcare workers from the Lagos state ministry of health in Nigeria. Using descriptive and structural equation modelling statistical analysis, the data revealed the relationship between workforce diversity and job satisfaction, workforce diversity and organisational commitment, and the role of job satisfaction on organisational commitment was also established.