1 results match your criteria: "Belgium (Dr Dal Lago). Dr Mattei is now with Denver Health Hospital[Affiliation]"
Gastrin-releasing peptide receptor expression in lung cancer.
Arch Pathol Lab Med
January 2014
From the Departments of Internal Medicine (Dr Mattei) and Pathology (Drs Meurer and Kulczynski), School of Medicine, the Laboratory of Molecular Neuropharmacology, Department of Pharmacology, Institute for Basic Health Sciences (Dr Roesler), and the Cancer Research Laboratory, University Hospital Research Center (CPE-HCPA) (Dr Macedo, Roesler, Brunetto, and Schwartsmann), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; the Departments of Urology (Dr Mattei) and Oncology (Mr Cano and Ms Batlle), University of Colorado, Denver; the Pathology Division, Department of Medicine, National Jewish Health, Denver, Colorado (Drs Achcar and Groshong); the National Institutes for Translational Medicine, Porto Alegre, Brazil (Drs Roesler and Schwartsmann); and the Department of Medical Oncology, Institut Jules Bordet, Brussels, Belgium (Dr Dal Lago). Dr Mattei is now with Denver Health Hospital, Denver, Colorado.
Context: Gastrin-releasing peptide receptors (GRPRs) activate mitogen-activated protein kinase signaling pathway primarily through epidermal growth factor receptor activation and are under investigation as a molecular target because they are overexpressed in several solid tumors.
Objective: To determine GRPR expression in both non-small cell lung carcinoma and small cell lung carcinoma, comparing results with clinical stages and demographic data.
Design: We analyzed the immunohistochemical expression of GRPR in 200 non-small cell lung carcinoma and 38 small cell lung carcinoma archival cases from 2004 to 2008.