Noncoordinating Anions as Key Modulators of Supramolecular Structures, Optical and Electrical Properties in Nickel(II) Complexes.

This study explores the synthesis, structural characterization, and examination of two nickel(II) complexes, [Ni( )](NO) (complex ) and [Ni( )](ClO) (complex ), using the newly synthesized organic heterocyclic chelating ligand [4-imidazole-2,6-di(pyrazinyl)pyridine]. Through single-crystal X-ray diffraction, we have detailed the crystal structures of these complexes, highlighting their distorted octahedral geometries and diverse supramolecular interactions including π···π stacking, anion···π, and hydrogen bonding. These interactions crucially influence the formation of distinct one- and two-dimensional supramolecular architectures.

Immunomodulatory and immune-toxicological role of nanoparticles: Potential therapeutic applications.

Nowadays, Nanoparticle-based immunotherapeutic research has invoked global interest due to their unique properties. The immune system is a shielding structure that defends living things from external threats. Before the use of any materials in drug design, it is essential to study the immunological response to avoid triggering undesirable immune responses in the body.

Role of Influenza A virus protein NS1 in regulating host nuclear body ND10 complex formation and its involvement in establishment of viral pathogenesis.

Influenza viral infection is a seasonal infection which causes widespread acute respiratory issues among humans globally. This virus changes its surface receptor composition to escape the recognition process by the host's immune cells. Therefore, the present study focussed to identify some other important viral proteins which have a significant role in establishment of infection and having apparent conserved structural composition.

Anti-cancer potentiality of linoelaidic acid isolated from marine Tapra fish oil (Ophisthopterus tardoore) via ROS generation and caspase activation on MCF-7 cell line.

The implication of inflammation in the pathophysiology of several types of cancers has been under intense investigation. Conjugated fatty acids can modulate inflammation and present anticancer effects, promoting cancer cell death. In this paper, we evaluated the efficacy of new conjugated fatty acids isolated from marine Opisthopterus tardoore (Tapra fish) in human breast cancer cell lines MCF-7.

Enhanced inflammasome-mediated inflammation and impaired autophagy in peripheral blood mononuclear cells is associated with non-alcoholic fatty liver disease severity.

Aims: Identification of the progress of non-alcoholic fatty liver disease (NAFLD) is crucial for their effective treatment. Circulating peripheral blood mononuclear cells (PBMC) could be a surrogate monitor instead of complicated and expensive biopsies. Changes in immuno-metabolic status in NAFLD patients may be reflected by an expression of different PBMC-specific molecular markers.

Antibacterial potency of cytocompatible chitosan-decorated biogenic silver nanoparticles and molecular insights towards cell-particle interaction.

In the study, leaf extract of Carica papaya was utilized for the biogenic fabrication process of chitosan functionalized silver nanoparticles (Ag-Chito NPs). HRTEM analysis revealed that the fabricated Ag-Chito NPs was spherical in shape, with an average particle size of 13.31 (±0.

Nanoinspired Biocompatible Chemosensors: Progress toward Efficient Prognosis of Arsenic Poisoning.

Diagnosing heavy metals poisoning in human beings is of paramount importance. In this work, we present the design of a biocompatible FeNiO hierarchical nanostructure-based sensor for ultraselective detection of arsenate (As(V)) ions in biological environments (e.g.

Effect of Fluidized Bed Drying, Matrix Constituents and Structure on the Viability of Probiotic ATCC 55544 during Storage at 4 °C, 25 °C and 37 °C.

The stabilization of probiotics for application in non-refrigerated food products is a challenging task. In the present study, probiotic () ATCC 55544 cells were immobilized in a dairy matrix comprising of whole milk powder, skim milk powder, or milk protein isolate using fluidized bed drying technology. The samples were taken out at different drying stages, with an apparent water activity (a) of a 0.

Manganese accumulation in probiotic Lactobacillus paracasei ATCC 55544 analyzed by synchrotron X-ray fluorescence microscopy and impact of accumulation on the bacterial viability following encapsulation.

Lactobacillus spp. are known to accumulate large amounts of inorganic manganese, which protects against oxidative damage by scavenging free radicals. The ability of probiotic L.

Smokeless tobacco induces toxicity and apoptosis in neuronal cells: a mechanistic evaluation.

Smokeless tobacco (SLT) or chewing tobacco has been a highly addictive practice in India across ages, posing major threat to the systemic health and possibly neurodegeneration. Earlier studies showed components of SLT could be harmful to neuronal health. However, mechanism of SLT in neurodegeneration remained unexplored.

Voltage-controlled NiO/ZnO p-n heterojunction diode: a new approach towards selective VOC sensing.

Metal oxide resistive gas sensors suffer from poor selectivity that restricts their practical applicability. Conventional sensor arrays are used to improve selectivity which increased the system complexity. Here, we have proposed a novel NiO/ZnO-based p-n junction single-diode device for selective sensing of several volatile organic compounds (VOCs) simultaneously by tuning bias voltage.

An association study of severity of intellectual disability with peripheral biomarkers of disabled children in a rehabilitation home, Kolkata, India.

The current investigation has identified the biomarkers associated with severity of disability and correlation among plethora of systemic, cellular and molecular parameters of intellectual disability (ID) in a rehabilitation home. The background of study lies with the recent clinical evidences which identified complications in ID. Various indicators from blood and peripheral system serve as potential surrogates for disability related changes in brain functions.

Spectroscopic investigations on Naphthol and Tetrahydronaphthol. A theoretical approach.

The computational efficiencies of the semi-empirical method have been compared with those of different ab-initio methods for positional isomers of Naphthol and Tetrahydro-naphthol type molecules. The efficiencies for computations in case of optimized structure, electronic absorption and emission properties are investigated. For that semi-empirical approach ZINDO and two different nature of ab-initio approaches such as TD-HF/6-311G(d,p) and TD-DFT/B3LYP/6-311G(d,p) were considered.