1 results match your criteria: "Beijing dThe Fourth Hospital of Hebei Medical University[Affiliation]"
Transplanted iNSCs migrate through SDF-1/CXCR4 signaling to promote neural recovery in a rat model of spinal cord injury.
Neuroreport
April 2014
aClinical College of General Hospital of Beijing Military Region, Anhui Medical University, Hefei bAffiliated Bayi Brain Hospital, General Hospital of Beijing Military Region cNeurosurgery Institute of Beijing Military Region, Beijing dThe Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
The ability of transplanted induced neural stem cells (iNSCs) to promote functional recovery after spinal cord injury and the mechanism by which iNSCs migrate to injured areas are poorly understood. Stromal cell-derived factor-1 (SDF-1) is a cytokine, whereas CXCR4 is its cognate receptor. The aim of this study was to determine whether SDF-1 regulates the migration of iNSCs and to explore the potential mechanism by which iNSCs promotes functional recovery.
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