Effect of artificial intelligence-based video-game system on dysphagia in patients with stroke: A randomized controlled trial.

Background And Aims: Post-stroke dysphagia is highly prevalent and causes complication. While video games have demonstrated potential to increase patient engagement in rehabilitation, their efficacy in stroke patients with dysphagia remains unclear. This aim of this study was to explore the effectiveness of the artificial intelligence-based video-game (AI-VG) intervention in improving swallowing function among stroke patients with dysphagia.

Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study.

Cervical spondylotic myelopathy (CSM) is a neurological disorder characterized by degenerative changes in the spinal cord and compression of the spinal cord and its adjacent structures due to various reasons, such as intervertebral disc herniation. The Japan Orthopaedic Association score is a disease-specific outcome tool that provides quantitative measurements for CSM patients. At present, no scholars have developed a model that can directly predict the prognosis of CSM patients.

Research hotspots and frontiers of vagus nerve stimulation in stroke: a bibliometric analysis.

Background: Vagus nerve stimulation (VNS) has emerged as a promising therapeutic approach for stroke treatment, drawing significant attention due to its potential benefits. However, despite this growing interest, a systematic bibliometric analysis of the research landscape is yet to be conducted.

Methods: We performed a comprehensive search of the Web of Science Core Collection (WoSCC) database for literature published between January 1, 2005, and August 31, 2024.

Global research hotspots and trends of theta burst stimulation from 2004 to 2023: a bibliometric analysis.

Background: Theta burst stimulation (TBS) has garnered widespread attention in the scientific community, but a comprehensive bibliometric analysis of TBS research remains absent. This study aims to fill this gap by elucidating the characteristics, hotspots, and trends in TBS publications over the past 20 years using bibliometric methods.

Methods: We retrieved TBS-related publications from January 1, 2004, to December 31, 2023, from the Web of Science Core Collection (WoSCC).

Adverse reactions associated with SSRIs and PD-1/PD-L1 inhibitors: a disproportionality analysis of the FDA Adverse Event Reporting System.

Background: Selective serotonin reuptake inhibitors (SSRIs) are the primary choice for antidepressant therapy in cancer patients with depression. Programmed death-1 and programmed cell death-ligand 1 (PD-1/PD-L1) play a critical role in immune checkpoint inhibitors. To date, there have been no studies reporting adverse events (AEs) associated with the real-world use of PD-1/PD-L1 inhibitors-SSRIs combination.

Bidirectional associations among gallstone disease, non-alcoholic fatty liver disease, kidney stone disease.

Background: A body of evidence has suggested bidirectional relationships among gallstone disease (GSD), non-alcoholic fatty liver disease (NAFLD), and kidney stone disease (KSD). However, the results are inconsistent, and studies on this topic in China are relatively few. Our goal is to explore the bidirectional associations among these three diseases through a multicenter study, systematic review, and meta-analysis.

The digital transformation of nursing practice: an analysis of advanced IoT technologies and smart nursing systems.

Facing unprecedented challenges due to global population aging and the prevalence of chronic diseases, the healthcare sector is increasingly relying on innovative solutions. Internet of Things (IoT) technology, by integrating sensing, network communication, data processing, and security technologies, offers promising approaches to address issues such as nursing personnel shortages and rising healthcare costs. This paper reviews the current state of IoT applications in healthcare, including key technologies, frameworks for smart nursing platforms, and case studies.

The effectiveness of theta burst stimulation for motor recovery after stroke: a systematic review.

Background: Stroke is the second leading cause of death and the third leading cause of disability worldwide. Motor dysfunction is a common sequela, which seriously affects the lives of patients. Theta burst stimulation (TBS) is a new transcranial magnetic therapy for improving motor dysfunction after stroke.

Aquatic therapy for spastic cerebral palsy: a scoping review.

Background: Cerebral palsy (CP) is a group of dysfunction syndrome. Spastic CP is the most common form of CP. As a specific treatment, aquatic therapy (AT) can improve spasticity, increase range of motion, and increase muscle strength due to its particular properties.

Liver transplantation and comprehensive rehabilitation in the reversal of hepatic myelopathy: a case report.

Hepatic myelopathy (HM) is a rare complication of end-stage chronic liver disease, primarily presenting as symmetrical lower limb weakness that progresses to spastic paralysis without sensory or sphincter dysfunction. We report a case of decompensated cirrhosis associated with hepatitis B virus and HM. The patient showed significant recovery after liver transplantation (LT) and comprehensive rehabilitation training.

Constructing a nomogram for the recurrence of tibial osteomyelitis after debridement surgery based on platelet to lymphocyte ratio at admission: a dual-center retrospective study from China.

Aim: To construction of a nomogram to predict the prognosis of patients with tibial osteomyelitis after debridement surgery.

Method: This study used binary logistic regression analysis to identify clinical independent predictive factors, and then used R language to construct a nomogram.

Result: The results showed that WBC (3.

Intermittent hypoxia training improves cerebral blood flow without cognitive impairment.

Objective: Brief exposure to intermittent hypoxia has been shown to potentially induce protective effects in the body. Animal studies suggest that intermittent hypoxia could increase cerebral blood flow and confer resistance to subsequent hypoxic-ischemic injury, yet clinical investigations are limited. This study aimed to evaluate the impact of a moderate short-term intermittent hypoxia protocol on cerebral blood flow and cognitive performance.

Knowledge mapping and research trends of brain-computer interface technology in rehabilitation: a bibliometric analysis.

Background: Although the application of brain-computer interface (BCI) technology in rehabilitation has been extensively studied, a systematic and comprehensive bibliometric analysis of this area remains lacking. Thus, this study aims to analyze the research progress of BCI technology in rehabilitation through bibliometric methods.

Methods: The study retrieved relevant publications on BCI technology in rehabilitation from the Web of Science Core Collection (WoSCC) between January 1, 2004, and June 30, 2024.

Clinical efficacy evaluation and safety study of Qishen Tongmai Yin I combined with moxibustion therapy on ASO: A retrospective study.

This study aimed to assess the therapeutic efficacy of moxibustion assisted therapy in combination with Qishen Tongmai Yin No. 1 on arteriosclerosis obliterans (ASO) patients. The impact on clinical symptoms, sign scores, foot dorsum temperature, foot dorsum artery blood flow, and overall clinical efficacy were analyzed.

Tofacitinib for ulcerative colitis: A promising treatment option.

A single center retrospective clinical study revealed the efficacy and safety of tofacitinib in the treatment of ulcerative colitis (UC). This study has clinical reference value but also has some limitations. Previous studies, including this clinical trial, have shown that tofacitinib could be a promising treatment option for UC, but further clinical research is required to prove this point.

Face Recognition-Driven Video Game for Dysphagia Rehabilitation in Stroke Patients: A Pilot Randomized Controlled Trial.

Objective: To explore the feasibility and effectiveness of face recognition-driven video game (FR-VG) swallowing training for stroke patients with dysphagia.

Design: A single-blind pilot randomized controlled trial.

Setting: A rehabilitation center.

Technology acceptance of the video game-based swallowing function training system among healthcare providers and dysphagia patients: A qualitative study.

Objective: Dysphagia is highly prevalent worldwide, causing serious complications. Video-game based rehabilitation training can increase dysphagia patient motivation and adherence. However, the acceptance of video game systems by patients and healthcare providers is still not fully explored.

A novel esterase regulates Klebsiella pneumoniae hypermucoviscosity and virulence.

Klebsiella pneumoniae, an emerging multidrug-resistant pathogen, exhibits hypermucoviscosity (HMV) as a critical virulence trait mediated by its capsular polysaccharide (CPS). Recent discoveries have determined acetylation as a significant modification for CPS, although its impact on HMV and virulence was previously unknown. This study elucidates the roles of two enzymes: Klebsiella pneumoniae Acetylated CPS Esterase (KpACE), an esterase that removes acetyl groups from CPS, and WcsU, an acetyltransferase that adds acetyl groups to CPS.

P4HB regulates the TGFβ/SMAD3 signaling pathway through PRMT1 to participate in high glucose-induced epithelial-mesenchymal transition and fibrosis of renal tubular epithelial cells.

Background: Diabetic nephropathy (DN) is a common complication of diabetes mellitus, and Prolyl 4-Hydroxylase Subunit Beta (P4HB) expression is increased in high glucose (HG)-induced renal tubular epithelial cells (TECs). But it's role in HG-induced TECs remains to be elucidated.

Methods: The HK-2 cells were induced using HG and transfected with SiRNA-P4HB.

Liver Function-Related Indicators and Risk of Gallstone Diseases-A Multicenter Study and a Systematic Review and Meta-Analysis.

We aim to examine the association between liver function-related indicators and gallstone disease (GSD) risk. The subjects who participated in the China Multicenter Physical Examination Cohort (CMPEC) were enrolled. Relative odds ratios (ORs) with 95% CIs and standardized mean differences (SMDs) were applied to investigate the effect of liver function-related indicators and GSD risk.