The Beijing Sentence Corpus II: A cross-script comparison between traditional and simplified Chinese sentence reading.

We introduce a sentence corpus with eye-movement data in traditional Chinese (TC), based on the original Beijing Sentence Corpus (BSC) in simplified Chinese (SC). The most noticeable difference between TC and SC character sets is their visual complexity. There are reaction time corpora in isolated TC character/word lexical decision and naming tasks.

Optimal dose and type of exercise improve walking velocity in adults with Parkinson's disease: a systematic review and Bayesian network meta-analysis.

To examine the dose-response relationship between specific types of exercise for improving walking velocity in Parkinson's disease (PD). This systematic review and network meta-analysis included searches of PubMed, Medline, Embase, PsycINFO, Cochrane Library, and Web of Science were searched from inception until February 18th, 2024. Data analysis was performed using R software with the MBNMA and RJAGS packages.

Effects of acute PM purification on cognitive function and underlying mechanisms: Evidence from integrating alternative splicing into multi-omics.

The relationship between fine particulate matter (PM) and cognition has been extensively investigated. However, the causal impact of acute PM purification on cognition improvement and the underlying biological mechanisms remain relatively opaque. Our double-blinded randomized controlled trial assessed the impact of acute PM purification on executive function, underpinned by multi-omics approaches including alternative splicing (AS) analysis.

Intratumoral Collagen Deposition Supports Angiogenesis Suggesting Anti-angiogenic Therapy in Armored and Cold Tumors.

A previous study classifies solid tumors based on collagen deposition and immune infiltration abundance, identifying a refractory subtype termed armored & cold tumors, characterized by elevated collagen deposition and diminished immune infiltration. Beyond its impact on immune infiltration, collagen deposition also influences tumor angiogenesis. This study systematically analyzes the association between immuno-collagenic subtypes and angiogenesis across diverse cancer types.

Exploratory Analysis of Unstable Surface Training: A Systematic Review and Meta-Analysis for Chronic Ankle Instability.

Objective: To conduct an exploratory systematic review and meta-analysis to evaluate the effect of unstable surface training on balance and hop function in individuals with chronic ankle instability (CAI).

Data Sources: Four major electronic databases were searched, including Cochrane Library, PubMed, Embase, and Web of Science, from January 1, 2000 to June 20, 2024.

Study Selection: Randomized controlled trials that compare unstable surface training with either general intervention or no intervention in individuals with CAI were included.

Effects of Supplementation With Different Specificities of Dietary Fiber on Health-Related Indicators in Adults With Overweight or Obesity: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Context: Dietary fiber (DF) exhibits variations in its chemical and physical complexity, as well as in its utilization by the gut microbiota. However, the impact of these differences on the health status of adults with overweight or obesity remains unclear.

Objective: This meta-analysis aimed to explore the varying effects of supplementing with different specificities of DF on the health of adults with overweight or obesity, providing guidance on selecting DF supplementation to improve health status.

Unveiling whole body vibration squat intensity insight from oxygen consumption and heart rate response.

This study explored the effects of training weight and amplitude in whole-body vibration (WBV) on exercise intensity, indicated by oxygen consumption (VO) and heart rate. In LOAD-study: ten participants performed squats under non-WBV and WBV (30 Hz 2 mm) conditions at 0%, 40%, and 80% bodyweight (BW). In AMPLITUDE-study: eight participants performed squats under non-WBV, low-amplitude WBV (30 Hz 2 mm), and high-amplitude WBV (30 Hz 4 mm) conditions with 0% and 40%BW.

Recent Advances in Nontargeted Screening of Chemical Hazards in Foodstuffs.

The emergence of several chemical substances continues to enrich and facilitate the development of food science, but their irrational use also poses a threat to food safety and human health. Nontargeted screening (NTS) has become an important tool for rapid traceability and efficient identification of chemical hazards in food matrices. NTS in food analysis is highly integrated with sample pretreatment, instrumental analysis platforms, data acquisition and analysis, and toxicology.

Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of osteochondral lesions of the talus.

Background: Surgical management methods for Hepple IV-V osteochondral lesions of the talus (OLT) are diverse. This study aimed to compare the clinical efficacy of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting in the treatment of medial Hepple IV-V OLT.

Methods: A retrospective analysis of clinical data from patients who underwent surgical treatment for Hepple IV-V OLT (2020-2023) was conducted.

Characterization of dynamic features in the walking videos of patients with adolescent idiopathic scoliosis based on moving entropy.

Adolescent idiopathic scoliosis (AIS), which typically occurs in patients between the ages of 10 and 18, can be caused by a variety of reasons, and no definitive cause has been found. Early diagnosis of AIS or timely recognition of progression is crucial for the prevention of spinal deformity and the reduction of the risk of surgery or postponement. However, it remains a significant challenge.

Effects of different tennis racket string tension on forehand stroke effect and racket dynamic impact.

This study investigates the effect of varying tennis racket string tension on stroke effect and the dynamic response of the racket. Using the YSV dynamic acceleration signal acquisition system and a portable radar speed gun collect data on racket acceleration, stress-strain signals, and ball speed from 15 male athletes. Stroke accuracy and depth were assessed according to the International Tennis Number.

Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials.

Background: Brain-derived neurotrophic factor (BDNF) may help middle-aged and older adults resist age-related neurodegenerative conditions and psychiatric disorders. Recent studies suggested that Traditional Chinese exercises (TCEs) may be a promising strategy to improve the BDNF levels of these populations, while the effectiveness has yet to be definitively confirmed due to the variances in the study designs and observations. Therefore, this systematic review and meta-analysis aimed to examine the effects of TCEs intervention on BDNF in middle-aged and older adults.

The Effect of Perceived Groove in Music on Effective Brain Connectivity during Cycling: An F-NIRS Study.

Introduction: Perceived groove, a complex and integrated musical characteristic, is considered a core factor in inducing synchronization between movement and music. This study aimed to employ functional near-infrared spectroscopy (fNIRS) to explore the effective connectivity (EC) changes among brain regions during cycling activities under different perceived groove conditions.

Methods: In a randomized crossover design, 18 university students performed 3-min cycling tasks under high (HG) and low (LG) perceived groove music conditions.

Peficitinib suppresses diffuse-type tenosynovial giant cell tumor by targeting TYK2 and JAK/STAT signaling.

Diffuse-type tenosynovial giant cell tumor (dTGCT) is a destructive but rare benign proliferative synovial neoplasm. Although surgery is currently the main treatment modality for dTGCT, the recurrence risk is up to 50%. Therefore, there is a great need for effective drugs against dTGCT with minor side effects.

Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials.

Background: Physical activity (PA) interventions have been shown to yield positive effects on cognitive functions. However, it is unclear which type of PA intervention is the most effective in children and adolescents with Neurodevelopmental Disorders (NDDs). This study aimed to compare the effectiveness of different types of PA interventions on cognitive functions in children and adolescents with NDDs, with additional analyses examining intervention effects across specific NDD types including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD).

Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake.

Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes with the total energy expenditure (TEE). In this study, we used the International Atomic Energy Agency Doubly Labeled Water Database to derive a predictive equation for TEE using 6,497 measures of TEE in individuals aged 4 to 96 years.

MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy.

Background: Breast cancer had been the most frequently diagnosed cancer among women, making up nearly one-third of all female cancers. Hormone receptor-positive breast cancer (HR+BC) was the most prevalent subtype of breast cancer and exhibited significant heterogeneity. Despite advancements in endocrine therapies, patients with advanced HR+BC often faced poor outcomes due to the development of resistance to treatment.

Shaping sustainable perceptions: The role of metaphors in Olympic news discourse.

The dissemination of sustainable development concepts in large international events like the Olympics has garnered great attention. As a major international sports event, the Beijing Winter Olympics served as an important platform for showcasing China's sustainable development philosophy through its official news coverage. In this context, metaphor, as a powerful cognitive tool, plays a crucial role in shaping public perception and facilitating the dissemination of values by mapping concrete source domains onto abstract target domains.

Patients with jumping sign exhibit rotational and bony structural abnormalities consistent with high-grade J-sign in recurrent patellar dislocation.

Purpose: To propose a new sign of patellar maltracking in recurrent patellar dislocation (RPD) and compare the differences in lower limb rotational and bony structural abnormalities among the different signs.

Patients And Methods: A retrospective study included 279 patients (mean age: 22 years; female: 81%) who underwent primary surgery for RPD over the past 4 years was performed. The patients were grouped based on the characteristics of patellar tracking: low-, moderate- and high-grade J-sign.

Effects of non-pharmacological interventions on depressive and anxiety symptoms in pregnant women: a systematic review and network meta-analysis.

Background: Given the distinctive physiological characteristics of pregnant women, non-pharmacological therapies are increasingly being used to improve depressive and anxiety symptoms. Our objective was to explore and compare the impact of various non-pharmacological interventions in improving depressive and anxiety symptoms, and to identify the most effective strategies for pregnant women with depressive and/or anxiety symptoms.

Methods: We conducted a systematic search of PubMed, Embase, the Cochrane Library, and Web of Science for randomized controlled trials (RCTs) that compared non-pharmacological interventions to usual care, from the inception of each database up to October 5, 2024.