193 results match your criteria: "Beijing Research Center for Preventive Medicine[Affiliation]"

Article Synopsis
  • Organophosphate esters (OPEs) and their metabolites (mOPEs) are increasingly recognized as harmful environmental pollutants, prompting the need for better analytical methods to measure them in human samples.
  • This study developed a streamlined analytical technique using cold-induced liquid-liquid extraction (CI-LLE) and HPLC-MS/MS to simultaneously detect 18 OPEs and 10 mOPEs in human serum, urine, and milk.
  • Results confirmed that the method had high sensitivity (with detection limits as low as 0.1 pg/mL), good recovery rates (80-123%), and minimal interference from the sample matrix, highlighting the widespread presence of OPEs and mOPEs in humans.
View Article and Find Full Text PDF
Article Synopsis
  • This study analyzed data from hospitals and vaccine administration records in Beijing, focusing on individuals vaccinated between January 2016 and December 2018 who experienced acute cardiovascular events.
  • The research involved 1,647 participants, revealing that the risk of cardiovascular events was reduced to 0.76 times the baseline level during 29-365 days post-vaccination.
  • The protective effect of the influenza vaccine was stronger in younger people and those without a history of cardiovascular issues, indicating that vaccines might help prevent cardiovascular diseases.
View Article and Find Full Text PDF

Time interval distribution of hepatitis B vaccine immunization among infants in China from 2017 to 2021.

Hum Vaccin Immunother

December 2024

Department of Laboratorial Science and Technology & Vaccine Research Center, School of Public Health, Peking University, Beijing, P. R. China.

Infant hepatitis B vaccine coverage in China is high, with over 95% of infants immunized; however, high vaccine coverage can often mask low timeliness. The vaccination interval between the second and third doses is not clearly defined by immunization guidelines in China. This retrospective cohort study assessed the time interval distribution of hepatitis B vaccination among a cohort of randomly selected live births from the Centers for Disease Control and Prevention across four provinces or municipalities in China between January 2017 and December 2021.

View Article and Find Full Text PDF

Debates surrounding the efficacy of influenza vaccination for survival benefits persist, and there is a lack of data regarding its duration of protection. A self-controlled case series (SCCS) and a 1:4 matched case-control study were conducted using the National Health Interview Survey (NHIS) and public-use mortality data from 2005 to 2018 in the United States. The SCCS study identified participants who received influenza vaccination within 12 months before the survey and subsequently died within 1 year of postvaccination.

View Article and Find Full Text PDF

Objective: To understand the epidemiological distribution characteristics of mountain-type zoonotic visceral leishmaniasis (MT-ZVL) in Yangquan City, Shanxi Province, China, from 2006 to 2021, to explore the influencing factors leading to the re-emergence of the epidemic, and to provide a basis for the formulation of targeted control strategies.

Methods: Case information spanning from 2006 to 2021 in Yangquan City was collected for a retrospective case-control study conducted from June to September 2022. A 1:3 matched ratio was employed.

View Article and Find Full Text PDF

Background: The COVID-19 pandemic has experienced various phases including outbreaks, a global health crisis, and eventual de-escalation from a public health emergency of international concern, significantly affecting the delivery and utilization of healthcare services. This study aimed to evaluate the impact of the COVID-19 pandemic on the coverage rate of routine immunization in children under varying prevalence conditions.

Methods: We conducted a retrospective, population-based cohort study in Beijing, China, utilizing stratified random sampling by birthdate to obtain a sample of 29,811 participants.

View Article and Find Full Text PDF

Governments must decide which vaccine priority to include in their public health programs. Using the modified Delphi and entropy method, we developed an indicator framework for vaccine inclusion at the national, provincial, municipal, and district/county levels, each containing three dimensions. In total, 4 primary indicators, 17 secondary indicators, and 45 tertiary indicators were selected, covering vaccine-preventable diseases, candidate vaccines, and social drivers of the supply and demand sides.

View Article and Find Full Text PDF

The intranasal spray COVID-19 vaccine was made available for the first time in China, it is necessary to understand receivers' satisfaction and experience toward the vaccine to help optimize vaccination service. A self-administered multicenter cross-sectional questionnaire survey was conducted in Beijing, China, in December 2022. The vaccination experience was evaluated through three dimensions: immediate tolerance, smooth progress, and time-saving.

View Article and Find Full Text PDF

Incidence and trends of 17 notifiable bacterial infectious diseases in China, 2004-2019.

BMC Infect Dis

May 2023

The State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong-Da Street, Fengtai District, Beijing, 100071, China.

Background: Certain bacterial infectious diseases are categorized as notifiable infectious diseases in China. Understanding the time-varying epidemiology of bacterial infections diseases can provide scientific evidence to inform prevention and control measures.

Methods: Yearly incidence data for all 17 major notifiable bacterial infectious diseases (BIDs) at the province level were obtained from the National Notifiable Infectious Disease Reporting Information System in China between 2004 and 2019.

View Article and Find Full Text PDF

Epidemiological features of Streptococcus pneumoniae in patients with acute respiratory tract infection in Beijing, China during 2009-2020.

J Infect Public Health

May 2023

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Department of Laboratorial Science and Technology & Vaccine Research Center, School of Public Health, Peking University, Beijing 100191, China; Global Center for Infectious Disease and Policy Research & Global Health and Infectious Diseases Group, Peking University, Beijing 100191, China. Electronic address:

Background: Streptococcus pneumoniae (S. pneumoniae) is one of the common pathogens causing acute respiratory tract infection (ARTI). The study aimed to investigate the prevalence of S.

View Article and Find Full Text PDF

Industry Distribution Characteristics of Benzene-Exposed Workers with Cytopenia - Four Provinces, China, 2020.

China CDC Wkly

December 2022

Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing Municipality, China.

What Is Already Known About This Topic?: Benzene is harmful to the hematopoietic system and can cause leukemia. However, benzene is still being used in various industries including furniture, rubber, plastic products, and metal product manufacturing.

What Is Added By This Report?: The white blood cell count of workers in general equipment, special equipment, chemical raw materials, and chemical products manufacturing decreased significantly.

View Article and Find Full Text PDF

Triclosan (TCS), triclocarban (TCC), and -chloro--xylenol (PCMX) are some of the most widely used antibiotics because of their broad-spectrum and highly-efficient bactericidal effects. In the context of disinfection, the National Standard GB 38598-2020 stipulates that the contents of the effective ingredients present in a disinfectant must be specified, wherein their range must fall within 90%-110% of the specified central value. To ensure a suitable product quality, analysis by high performance liquid chromatography (HPLC) is recommended by both the GB/T 27947-2020 and GB/T 34856-2017.

View Article and Find Full Text PDF

Human exposure to a mixture of endocrine disruptors and serum levels of thyroid hormones: A cross-sectional study.

J Environ Sci (China)

March 2023

NHC Key Laboratory of Food Safety Risk Assessment, Chinese Academy of Medical Science Research Unit (No. 2019RU014), China National Center for Food Safety Risk Assessment, Beijing 100022, China.

Article Synopsis
  • The study investigated the impact of multiple endocrine disruptors (EDCs) on thyroid hormones in 177 healthy adults from China, measuring both serum thyroid hormone levels and urinary EDCs.
  • Results showed that, after accounting for various factors, bisphenol F (BPF) significantly correlated with lower levels of several thyroid hormones, while certain phthalate metabolites were positively linked to thyroid hormones.
  • The researchers highlighted a dose-response relationship between the mixture of EDCs and thyroid hormone levels, particularly emphasizing the strong influence of BPF on thyroid function, suggesting that even low-level EDC exposure could disrupt hormonal balance in healthy adults.
View Article and Find Full Text PDF

A case-control study of urinary concentrations of bisphenol A, bisphenol F, and bisphenol S and the risk of papillary thyroid cancer.

Chemosphere

January 2023

Research Unit of Food Safety, Chinese Academy of Medical Sciences (No. 2019RU014); NHC Key Lab of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment (CFSA), Beijing 100022, China.

Article Synopsis
  • The global incidence of thyroid cancer, particularly papillary thyroid cancer (PTC), has significantly risen, with some endocrine disruptors possibly linked to cancer processes, though specific relationships with bisphenol analogs remain uncertain.
  • A case-control study investigated the relationship between urinary concentrations of bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS) and the risk of PTC, finding a positive association with BPF while BPA and BPS showed negative associations.
  • The results indicated that BPF exposure increases PTC risk, notably in non-smoking women, warranting further research to confirm these findings.
View Article and Find Full Text PDF

Acute hepatitis of unknown aetiology among children around the world.

Infect Dis Poverty

November 2022

Department of Laboratorial Science and Technology & Vaccine Research Center, School of Public Health, Peking University, No. 38 Xue-Yuan Road, Haidian District, Beijing, 100191, People's Republic of China.

By 26 August 2022, the number of cases of acute hepatitis of unknown etiology (AHUA) has drastically increased to 1115 distributed in 35 countries that fulfill the World Health Organization definition. Several hypotheses on the cause of AHUA have been proposed and are being investigated around the world. In the recent United Kingdom (UK) report, human adenovirus (HAdV) with adeno-associated virus (AAV) co-infection is the leading hypothesis.

View Article and Find Full Text PDF

The objective of this study is to investigate the epidemiological and clinical characteristics of the acute respiratory tract infections (ARTI) caused by respiratory syncytial virus (RSV) among the population of all age categories in Beijing, China. Outpatients and inpatients with ARTI were enrolled from 35 sentinel hospitals in Beijing between March 2015 and February 2019. They were interviewed and their medical records were collected using a standardized form.

View Article and Find Full Text PDF

This real-world study explores the effect of coronavirus disease 2019 (COVID-19) inactivated vaccines on the prevention of asymptomatic or mild Delta or Omicron variant infections progressing to pneumonia. Association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia cases and vaccination was measured with a multivariable logistic regression, stratified by genotype and age groups. We recruited 265 cases (111 (41.

View Article and Find Full Text PDF

[The progress on post-exposure prophylaxis of tetanus immunological preparation in adults].

Zhonghua Yu Fang Yi Xue Za Zhi

July 2022

Institute for Immunizations and Vaccines, Beijing Center for Disease Control and Prevention, Beijing 100050, China Beijing Research Center for Preventive Medicine, Beijing 100050, China.

The tetanus has been eliminated in the pregnancy women and newborns in China. However, there is a gap for adult tetanus immunization, and the risk of tetanus infection cannot be ignored. In order to clearly understand the effect of the tetanus to human beings and the current use of tetanus immunological preparation for adult post-exposure prophylaxis, the incidence of the tetanus, the use status of tetanus immunological preparation and recommendations for post-exposure prophylaxis at home and abroad were reviewed and summarized, which may provide academic evidence for post-exposure prophylaxis procedures and use of tetanus immunological preparation.

View Article and Find Full Text PDF

Background: The purpose of this study was to assess the level of knowledge, attitude and practice of COVID-19 among staff in China-Guinea Friendship Hospital, and to confirm the effect of nosocomial infection management.

Methods: This cross-sectional study was conducted in December 2021. Information on socio demographic data, knowledge, attitude and practices related to COVID-19 was collected through a self-administered questionnaire.

View Article and Find Full Text PDF

Objective: To analyze the influenza vaccination trend of hospitalized elderly people (≥ 60 years old) in Beijing from 2013 to 2019.

Methods: The influenza vaccination status and hospitalization information of elderly people were extracted from the Beijing Elderly Influenza Vaccination database (2013-2019) and the Beijing Urban Employee Basic Medical Insurance database (2013-2019), se-parately. The influenza vaccine coverage rates and annual percentage change were calculated to compare the vaccination trends of elderly people hospitalized due to different diseases.

View Article and Find Full Text PDF

Cholera Caused by a New Clone of Serogroup O1 - Beijing Municipality, China, June 2021.

China CDC Wkly

January 2022

Beijing Center for Disease Prevention and Control, Beijing Research Center for Preventive Medicine, Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing, China.

View Article and Find Full Text PDF

Industry Distribution Characteristics of Benzene-Induced Leukemia - 7 PLADs, China, 2005-2019.

China CDC Wkly

April 2022

Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.

What Is Already Known About This Topic?: In the 1980s. benzene-induced leukemia (BIL) mainly occurred in shoemaking and painting industries. Now the industry distribution of benzene-induced leukemia may have changed over time.

View Article and Find Full Text PDF

Genetic diversity and epidemiological features of respiratory syncytial virus, Beijing, 2015-2019: A multicenter and all-age groups study.

J Infect

July 2022

College of Public Health, Capital Medical University. No.10 West, You'anmen Avenue, Fengtai District, Beijing 100069, PR China; Institute for Immunization and Prevention, Beijing Center for Disease Control and Prevention, Beijing Research Center for Preventive Medicine, No.16 Hepingli Middle Street, Dongcheng District, Beijing 100013, PR China. Electronic address:

Objective: To investigate the genetic variability and the epidemiological features of respiratory syncytial virus (RSV) in Beijing during five consecutive seasons from 2015 to 2019.

Methods: We collected 36,927 samples (ages ranged from 1 day to 101 years old) from cases with acute respiratory tract infections (ARTI) using the Respiratory Pathogens Surveillance System (RPSS) in Beijing, 2015-2019. G gene sequencing and phylogenetic analysis were performed to identify RSV genotypes, clusters, and amino acid (aa) changes.

View Article and Find Full Text PDF

Understanding immune memory to COVID-19 vaccines is critical for the design and optimal vaccination schedule for curbing the COVID-19 pandemic. Here, we assessed the status of humoral and cellular immune responses at 1, 3, 6, and 12 months after two-dose CoronaVac vaccination. A total of 150 participants were enrolled, and 136 of them completed the study through the 12-month endpoint.

View Article and Find Full Text PDF