2,965 results match your criteria: "Beijing Jishuitan Hospital[Affiliation]"
Orphanet J Rare Dis
December 2024
Thrombosis Research Center, Beijing Jishuitan Hospital, Capital Medical University, Xicheng District, Beijing, 100035, China.
Background: Identification of mutations in the SERPINC1 has illuminated the intricate pathways underlying antithrombin (AT) deficiency. Our group identified a variation in the SERPINC1 gene (c.964 A > T, p.
View Article and Find Full Text PDFMol Med Rep
March 2025
School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China.
Rotator cuff tears (RCT) can cause shoulder pain, weakness and stiffness, significantly affecting daily life. Analysis of the GSE103266 dataset revealed significant changes in the mTOR/PI3K/Akt signaling pathway and lipid metabolism‑related pathways, suggesting that fatty infiltration may affect RCT. The analysis indicated that the ubiquitin ligase NEDD4 plays a critical role in RCT.
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Foot and Ankle Surgery, Beijing Jishuitan Hospital, Capital Medical University, No.31, Xinjiekou East Street, Xicheng District, Beijing, 100035, China.
Background: Hallux valgus (HV) is a multiplanar deformity and surgical treatment is often guided by two-dimensional radiographic parameters. This study assessed the reliability and accuracy of the AIR classification(The first metatarsal head's lateral edge can be delineated as angular (type A), round (type R), or intermediate (type I) through visual inspection or circle measurements on weight-bearing radiographs.)commonly used in clinical settings to categorize the shape of the lateral edge of the first metatarsal head, against measurements from weight-bearing computed tomography (WBCT).
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Orthopaedics and Traumatology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China.
Background: Early weight bearing is crucial for fracture healing after osteosynthesis for intertrochanteric fractures (ITFs). The optimal period to start weight bearing after surgery is still under debate. The aim of this study was to compare immediate weight bearing (IWB) as tolerated with delayed weight bearing (DWB) following intramedullary fixationin elderly ITF patients.
View Article and Find Full Text PDFMol Neurobiol
December 2024
Joint Laboratory for Research & Treatment of Spinal Cord Injury in Spinal Deformity, Laboratory for Clinical Medicine, Capital Medical University, Fengtai District, Beijing, 100069, China.
Distraction spinal cord injury (DSCI) is a severe complication following scoliosis correction surgery, for which there are currently no effective clinical treatments. This study aims to evaluate the inhibitory effects of rutin, a natural product, on inflammation in DSCI and to investigate the underlying mechanisms. In vitro, microglial cells were exposed directly to rutin to assess its ability to inhibit lipopolysaccharide (LPS)-induced inflammation.
View Article and Find Full Text PDFCardiovasc Diabetol
December 2024
Cardiology Department, Beijing Anzhen Hospital, Anzhen Road No. 2, Chaoyang District, Beijing, China.
Background: Atherogenic index of plasma (AIP) has been recommended as a marker of plasma atherogenicity. The impact of AIP on plaque characteristics is not fully understood.
Purpose: The study investigates the relationship between AIP and coronary plaque features in patients with acute coronary syndrome (ACS).
Eur Radiol
December 2024
Department of Radiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Objectives: Our study aimed to elucidate synovial plica (SP) of the elbow histological characteristics and the anatomical relationship with adjacent structures. Subsequently, we sought to assess the relationship between SP and clinical symptoms as well as magnetic resonance imaging (MRI) features in patients with chronic lateral epicondylitis.
Methods: MRI was performed on eight cadaveric elbows specimens.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
December 2024
Department of Orthopedics, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Objective: To compare the mid- and long-term effectiveness of patellar resurfacing versus non-resurfacing in primary total knee arthroplasty (TKA).
Methods: Twenty-six patients who underwent bilateral TKA between March 2013 and September 2015 were selected as the study subjects. One side was randomly chosen for patellar resurfacing (resurfacing group), and the other side was not (control group).
Zhonghua Wai Ke Za Zhi
December 2024
Department of Orthopedic Oncology Surgery, Beijing Jishuitan Hospital, Capital Medical University, National Center for Orthopedics, Peking University Fourth Clinical Medical College, Beijing100035, China.
Giant cell tumor of bone (GCTB) is a common locally aggressive junctional primary bone tumor, whose clinical treatment becomes more difficult once combined with pathological fracture. Extended curettage and en-bloc resection are common surgical procedures for treating GCTB, and drugs such as receptor activator of nuclear factor-κB ligand(RANKL) inhibitors and bisphosphonates have been successfully used. Curettage is recommended for patients with Campanaccigrade Ⅱor Campanaccigrade Ⅲ with localized soft tissue invasion only and simple fractures with intact bone structure.
View Article and Find Full Text PDFBeijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Urology, Beijing Jishuitan Hospital, Capital Medical Universitay, Beijing 100035, China.
Objective: To evaluate the surgical methods for treating distal urethral stricture.
Methods: The clinical data of 80 patients with distal urethral stricture in Beijing Jishuitan Hospital, Captial Medical University between January 2018 and December 2022 were retrospectively collected. Including male genital lichen sclerosus (MGLS) 33 cases, iatrogenic injury 25 cases, postoperative hypospadias 12 cases, and other causes such as trauma 10 cases.
World J Gastrointest Oncol
December 2024
Graduate School, Peking University China-Japan Friendship School of Clinical Medicine, Beijing 100029, China.
Background: The 5-year survival rate of patients with colorectal cancer (CRC) in China is only 56.9%, highlighting the need for new therapeutic drugs. Previous studies have shown that matrine exhibits antitumor effects by inducing apoptosis.
View Article and Find Full Text PDFInt J Womens Health
December 2024
Department of Gynecology and Obstetrics, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, People's Republic of China.
Background: Endometriosis and its associated gynecological diseases such as female infertility and primary ovarian failure (POF), impose a long-term disease burden on women. This study aims to explore the causal relationships between these conditions through a two-sample bidirectional Mendelian randomization (MR) study.
Methods: We utilized large-scale GWAS data and conducted bidirectional MR analyses using methods such as Inverse Variance Weighted (IVW) and MR-Egger to assess the causal relationships between endometriosis and female infertility, POF, amenorrhoea, and oligomenorrhoea.
Orthop Surg
December 2024
Department of Radiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Objectives: Benign and malignant intraosseous schwannomas are rare, and primarily documented in case reports. This study aims to elucidate the differences in clinical features and imaging manifestations between these tumors. This will help clinicians identify malignant lesions at an early stage, reliable guide treatment decisions, and accurately predict outcomes.
View Article and Find Full Text PDFArthroscopy
December 2024
Department of Orthopaedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Faculty of Medicine, Universitas Trisakti, Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia.
Purpose: To evaluate the minimum 12-month clinical and radiological outcomes of combined superior capsular reconstruction (SCR) and lower trapezius transfer (LTT) for posterosuperior irreparable massive rotator cuff tears (IMRCTs).
Methods: Patients with posterosuperior IMRCTs and severe fatty infiltration (Goutallier grades 3 or more) in the infraspinatus who underwent SCR +LTT were retrospectively reviewed. A double-folded fascia lata autograft with one layer of polypropylene mesh inside was used for SCR and an Achilles tendon allograft was used to connect the tendon of lower trapezius to the greater tuberosity.
Int Immunopharmacol
January 2025
Department of Orthopaedics, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, PR China. Electronic address:
Intervertebral disc degeneration (IVDD) is the primary cause of low back pain (LBP). Enhanced inflammation and reactive oxygen species (ROS) levels can cause apoptosis, which is one of the initial factors of IVDD. Our previous study showed that daphnetin (DAP) alleviates IVDD; however, the underlying mechanisms remain unknown.
View Article and Find Full Text PDFJ Knee Surg
December 2024
Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Capital Medical University, Fourth Clinical College of Peking University, Beijing, China.
Introduction: An adductor canal block (ACB) is widely accepted as a regional nerve block for pain management following total knee arthroplasty (TKA). However, no consensus exists concerning whether the analgesic effect is greater when joint surgeons perform intra-articular ACBs (IA-ACBs) or when anesthesiologists perform ultrasound-guided ACBs (UG-ACBs). We hypothesized that intra-articular ACBs (IA-ACBs) performed by joint surgeons and UG-ACBs performed by anesthesiologists based on peri-articular injections (PAI) would yield equivalent analgesic effects.
View Article and Find Full Text PDFAnn Plast Surg
January 2025
From the Department of Burn and Plastic, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Background: Deep burns to the upper abdomen that involve the submammary fold can lead to downward contracture and may cause significant asymmetry in a single breast, which can cause serious aesthetic and psychological problems, especially when they occur during childhood or before puberty. The objective of this study was to establish a practical treatment approach for postburn unilateral breast reconstruction after downward contracture.
Method: We conducted this retrospective review of patients with postburn unilateral breast deformity who underwent reconstruction using the expanded lateral thoracic flap and torso advancement flap from 2016 through 2021.
Kidney Dis (Basel)
December 2024
Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Background: Precise regulation of cell-cell communication is vital for cell survival and normal function during embryogenesis. The Wnt protein family, a highly conserved and extensively studied group, plays a crucial role in key cell-cell signaling events essential for development and regeneration. Congenital anomalies of the kidney and urinary tract (CAKUT) represent a leading cause of chronic kidney disease in children and young adults, and include a variety of birth abnormalities resulting from disrupted genitourinary tract development during embryonic development.
View Article and Find Full Text PDFOrthop Surg
December 2024
Department of Orthopaedics and Traumatology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Objective: Plate fixation is the preferred method for treating forearm shaft fractures. However, it remains controversial regarding the necessity of implant removal after bone union. This review aims to assess refracture risk after plate removal.
View Article and Find Full Text PDFTissue Eng Part C Methods
December 2024
National Center for Orthopaedics, Beijing Jishuitan Hospital, Capital Medical University, Beijing Research Institute of Traumatology and Orthopaedics, Beijing, 100035, P.R. China.
The failure of orthopedic implants can significantly impact patients physiologically, psychologically, and economically. A bibliometric study of the field of surface modification for antimicrobial purposes in orthopedic implants provides insights into its developmental trajectory and offers valuable predictions for future advancements, thus playing a pivotal role in guiding research in this domain. Relevant publications on surface modification for antimicrobial purposes in orthopedic implants published between 2014 and 2024 were selected from the Web of Science (Core Collection) dataset and analyzed using VOSviewer and Citespace.
View Article and Find Full Text PDFACS Biomater Sci Eng
December 2024
Department of Spine Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
In this study, we explore the cartilage defect repair mechanism by phosphocreatine-grafted chitosan hydrogels loaded with berberine-treated ATDC5 cells (CSMP@BBR@ATDC5). Under the optimal concentrations of LPS and BBR ideal conditions, ATDC5 cell toxicity and proliferation were detected with AM/PI and EdU staining. Additionally, qPCR and Western blot were employed to detect the expression of the SIRT1/BMP4 signaling pathway and chondrogenic-related factors in ATDC5 cells.
View Article and Find Full Text PDFPLoS One
December 2024
Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Objective: This study aimed to compare the surgical outcomes in patients with endometrial cancer who underwent either single-port laparoscopic hysterectomy (SPLH) or multi-port laparoscopic hysterectomy (MPLH).
Methods: We conducted a systematic literature search from the earliest records available up to May 2023. The databases searched included PubMed, Embase, ClinicalTrials.
Hip Int
December 2024
Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Purpose: Considering the low survival rate for the numerous hip-preserving procedures developed for treating early-stage osteonecrosis of the femoral head (ONFH), this study aimed to evaluate short-term clinical outcomes following avascular necrosis (AVN) CAGE implantation.
Methods: 58 hips with early-stage ONFH (44 with Association Research Circulation Osseous [ARCO] stage 2 and 14 with stage 3A) treated with the AVN CAGE between August 2018 and December 2021 were included. The survival rates were analysed using radiographic progression and conversion to subsequent total hip arthroplasty (THA) as endpoints.
J Hand Surg Eur Vol
December 2024
Department of Hand Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
We report a case series of trans-trapezium carpometacarpal dislocation of the thumb and propose a classification to help with decision-making for this injury.
View Article and Find Full Text PDFMed Gas Res
December 2024
Department of Knee Preservation Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Medical ozone is a molecule composed of three oxygen atoms with anti-inflammatory, analgesic, and antioxidant functions. Ozone therapy (O3 or O2- O3) for knee osteoarthritis has gradually received increasing attention from researchers in recent years. Here, we discuss the research hotspots and development trends of ozone therapy for knee osteoarthritis through literature visualization and analysis.
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