2 results match your criteria: "Beijing Institute of Geriatrics and Xuanwu Hospital of Capital University of Medical Sciences[Affiliation]"
Genetic association between low-density lipoprotein receptor-related protein gene polymorphisms and Alzheimer's disease in Chinese Han population.
Neurosci Lett
October 2008
Department of Neurology and Neurobiology, Key Laboratory of Neurodegenerative Diseases for Ministry of Education, Beijing Institute of Geriatrics and Xuanwu Hospital of Capital University of Medical Sciences, 100053 Beijing, China.
Alzheimer's disease (AD) is the most common neurodegenerative disorders in the elderly. Low-density lipoprotein receptor-related protein (LRP), as a receptor of apolipoprotein E (APOE), APP, and alpha2 macroglobulin (alpha2-M), keeps the balance between degeneration and production of beta-amyloid protein (Abeta) clearance. Its gene had been defined as a candidate gene for AD, but the results were not universal.
View Article and Find Full Text PDFA common A340T variant in PINK1 gene associated with late-onset Parkinson's disease in Chinese.
Neurosci Lett
December 2006
Department of Neurobiology and Neurology, Beijing Institute of Geriatrics and Xuanwu Hospital of Capital University of Medical Sciences, Beijing 100053, China.
Parkinson's disease (PD) is a complex neurodegenerative disease with genetic risk factors. Common variants in genes implicated in hereditary forms of parkinsonism may be predisposing factors for sporadic PD. Recent studies have demonstrated that mutations in PINK1 (PARK6 locus) gene, encoding PTEN-induced kinase 1, are associated with both familial recessive and sporadic early onset parkinsonism.
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