6 results match your criteria: "Beijing Hospital of Ministry of Public Health[Affiliation]"

Glargine insulin/gliclazide MR combination therapy is more effective than premixed insulin monotherapy in Chinese patients with type 2 diabetes inadequately controlled on oral antidiabetic drugs.

Diabetes Metab Res Rev

October 2015

Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai, China.

Background: The aim of this study is to compare the efficacy and safety of once-daily insulin glargine plus gliclazide modified release combination therapy versus twice-daily premixed insulin monotherapy in Chinese type 2 diabetic patients insufficiently controlled by oral antidiabetic agents.

Methods: In a 12-week, multicenter, randomized, parallel-group clinical trial, patients with poor glycaemic control (fasting plasma glucose ≥ 7.0 mmol/L and 7.

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Effect of indomethacin and lactoferrin on human tenocyte proliferation and collagen formation in vitro.

Biochem Biophys Res Commun

November 2014

Centre for Nanohealth, College of Medicine, Swansea University, Singleton Park, Swansea, UK SA2 8PP. Electronic address:

Article Synopsis
  • NSAIDs like indomethacin are commonly used for injuries and post-surgery, but high doses can inhibit the growth and collagen formation of human tenocytes (tendon cells).
  • Lactoferrin, an anabolic agent, promotes tenocyte survival and collagen production, especially in low serum conditions.
  • When combined with indomethacin, lactoferrin can partially counteract the negative effects of the NSAID on tenocyte growth and health, indicating its potential as a supportive treatment.
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In vitro two-dimensional and three-dimensional tenocyte culture for tendon tissue engineering.

J Tissue Eng Regen Med

March 2016

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

In order to examine the differentiation potential of the tenocytes expanded in our defined culture medium (reported previously) and the effect of sequential combination of the two culture conditions on human tenocytes, a two-dimensional and three-dimensional experimental approach was used. Human tenocytes were sequentially exposed to 1% fetal bovine serum (FBS) + 50 ng/ml platelet-derived growth factor-BB (PDGFBB ) + 50 ng/ml basic fibroblast growth factor (bFGF) for the first 14 days (expansion phase) followed by a further 14-day culture in the presence of 10 ng/ml transforming growth factor β-3 plus 50 ng/ml insulin-like growth factor 1, but in the absence of serum (differentiation phase). The results showed that by sequential treatment of human tenocytes maintaining a long-term two-dimensional tenocyte culture in vitro for up to 28 days was possible.

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Objective: To compare the phonetic parameters changes of titanium denture base materials to that of conventionally processed poly methyl methacrylate (PMMA) resin.

Methods: Forty-two edentulous patients were included in this study. Each patient received two sets of dentures.

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Objective: To study the relationship between cholelithiasis and previous cholecystectomy for colorectal cancer.

Method: Retrospectively, the frequency of occurrence of gallstones and cholecystectomy for 238 patients with colorectal cancer diagnosed pathologically was compared with that of 395 matched controls for age and sex. The patients were checked by type B ultrasonography or had cholelithiasis and underwent cholecystectomy.

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