Cell cycle arrest of human bronchial epithelial cells modulated by differences in chemical components of particulate matter.

There is increasing interest in understanding the role of airborne chemical components in modulating the cell cycle of human bronchial epithelial (HBE) cells that is associated with burden of cardiopulmonary disease. To address this need, our study collected ambient PM (particles with aerodynamic diameter less than or equal to 10 μm) and PM (particles with aerodynamic diameter less than or equal to 2.5 μm) across four sampling sites in Beijing during the year of 2015.

Thymol derivatives with antibacterial and cytotoxic activity from the aerial parts of .

Three new thymol derivatives, 7-formyl-9-isobutyryloxy-8-hydroxythymol (1), 7,9-di-isobutyryloxy-8,10-dehydrothymol (2) and 2α-methoxyl-3β-methyl-6-methylol-2,3-dihydrobenzofuran (3), along with five known ones (4-8), were isolated from the aerial parts of the invasive plant . Their structures were elucidated by extensive spectroscopic analysis and they were all isolated from the aerial part of for the first time. These compounds, except 8, selectively showed antimicrobial activity against three Gram-(+) and two Gram-(-) bacterial strains.