1,340 results match your criteria: "Beijing 100010; Huairou Hospital of Beijing Hospital of TCM[Affiliation]"

To compare the efficacy and safety of low-power holmium laser enucleation of the prostate (LP-HoLEP) with plasma kinetic resection of prostate (PKRP). Sixty-three patients treated with transurethral LP-HoLEP (observation group) and 68 patients treated with transurethral PKRP (control group) at Beijing Hospital of Traditional Chinese Medicine from November 2019 to November 2022 were retrospectively compared with regard to operation duration, intra-operative blood loss, prostate resection ratio, postoperative bladder irrigation time, postoperative indwelling urinary catheter time, postoperative urinary incontinence incidence, International Prostate Symptom Scale (IPSS), maximum urine flow rate (Qmax), and residual urine volume (RUV). In both groups, postoperative IPSS, Qmax, and RUV were significantly improved compared to preoperative values (P < 0.

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Biotransformation analysis of daidzin in vitro based on fecal bacteria and probiotics.

J Pharm Biomed Anal

December 2024

Guang'an Men Hospital, China Academy of Chinese Medical Sciences, Beijing 100010, China. Electronic address:

Daidzin, as one of isoflavone glycosides, has been reported to have multiple activities with few absorbed into body. However, the metabolic behavior of daidzin by intestinal flora has not been researched, that this defect severely constrains its applications. In this study, daidzin and its metabolites were qualitatively and quantitatively analyzed by HPLC and ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) in the fermentation system for daidzin and fecal bacteria.

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Invasive meningococcal disease, caused by (), is a critical global health issue, necessitating swift and precise diagnostics for effective management and control. Here, we introduce a novel diagnostic assay, NM-RT-MCDA, that combines multiple cross displacement amplification (MCDA) with real-time fluorescence detection, targeting a specific gene region in the genome. The assay utilizes a primer set designed for high specificity and incorporates a fluorophore-quencher pair with a restriction endonuclease site for real-time monitoring.

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A liquid chromatography-tandem mass spectrometry method was established and validated for determining the concentrations of costunolide(CO), piperine(PI), agarotetrol(AG), glycyrrhizic acid(GL), vanillic acid(VA), and glycyrrhetinic acid(GA) in rat plasma. This method was then applied to the toxicokinetic study of these six compounds in rats with chronic cerebral ischemia(CCI) following multiple oral doses of Zhachong Shisanwei Pills. Finally, the effects of continuous multiple-dose administration of Zhachong Shisanwei Pills on the liver of CCI rats were investigated.

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Inter-regional input-output (IRIO) tables are essential for socioeconomic and environmental analysis. This paper compiled a continuous time series of Chinese IRIO tables with a detailed regional and sectoral classification, covering a longer period from 1987 to 2017 than existing Chinese IRIO tables. Additionally, we integrated the China provincial CO emission inventory data (1987-2017) to analyze trends and identify the main driving factors behind regional economic linkages and carbon emissions changes.

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Modifying effects of prenatal exposure to rare earth elements on birth outcomes through maternal thyroid function in early pregnancy.

Environ Pollut

December 2024

Department of Nutrition and Food Safety, Peking Union Medical College, Research Unit of Food Safety, Chinese Academy of Medical Sciences, Beijing, 100010, China; NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, 100010, China. Electronic address:

The potential health effects of exposure to rare earth elements (REEs) remain largely unexplored. This prospective cohort study aimed to elucidate the association between early pregnancy REE exposure and maternal thyroid function, as well as neonatal birth outcomes, in a cohort of pregnant women in Beijing, China. Additionally, the study explored the mediating role of thyroid homeostasis in the effects of REE exposure.

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Enhanced Basal-Plane Catalytic Activity of MoS by Constructing an Electron Bridge for High-Performance Lithium-Sulfur Batteries.

Nano Lett

December 2024

Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Negative Carbon Technologies, Soochow University, Suzhou 215123, China.

MoS is a promising sulfur host material for lithium-sulfur (Li-S) batteries, but its low conductivity and limited active edge sites largely inhibit the catalytic activity toward the conversion of lithium polysulfides (LiPSs). Herein, we propose an electron bridge strategy by combining interlayer structure modification and electronic modulation to activate the basal-plane catalytic activity of MoS for the highly efficient catalytic conversion of LiPSs. As validated by experimental characterizations and theoretical calculations, the proposed strategy not only creates a conductive network but also induces delocalized electron redistribution within the MoS basal planes, leading to facilitated interfacial charge transfer kinetics and accelerated LiPSs redox kinetics.

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For HCQ retinopathy with CME, acupuncture combined with periocular injection can be used to improve the CME and protect the central vision. Subsequent research endeavors involving a more extensive cohort and extended observation periods are warranted to evaluate the effectiveness and safety profile of the intervention.

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Long-term weight change, incident cardiovascular disease and all-cause mortality among diabetic adults.

Diabetes Res Clin Pract

January 2025

Center for Evidence-Based Medicine, Capital Institute of Pediatrics, Beijing 100020, China. Electronic address:

Article Synopsis
  • The study investigated how weight changes from young adulthood to middle age affect the risk of cardiovascular disease (CVD) and all-cause mortality in diabetic adults in the U.S.
  • Researchers analyzed data from the NHANES survey covering a span of 29.4 years, focusing on adults aged 40-79 who provided information on their weight at age 25 and 10 years before enrollment.
  • They found that weight loss was linked to a lower risk of CVD and mortality compared to maintaining obesity, with a significant potential reduction in CVD cases if individuals had maintained a non-obese status throughout their lives.
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  • Heat shock protein A4 is found to be highly expressed in cutaneous malignant melanoma (CMM) and its levels correlate with poor patient prognosis.* -
  • Research showed that targeting this protein can inhibit melanoma cell growth and it has diagnostic potential as indicated by ROC curve analysis.* -
  • Analysis of gene variations and protein interactions suggests that heat shock protein A4 plays a role in immune suppression in the tumor microenvironment of CMM.*
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Influence of vitamin D supplementation and the vaginal microenvironment on human papillomavirus infection.

Afr J Reprod Health

October 2024

Department of Gynecology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.

Article Synopsis
  • The study investigated how the vaginal microenvironment affects HPV infection and the role of vitamin D in this context, using data from 512 participants categorized into HPV positive and negative groups.
  • It was found that the high-risk HPV (HR-HPV) group had higher abnormal rates of certain microbial and biochemical markers compared to the HPV negative group, indicating a link between these factors and HPV infection.
  • Vitamin D supplementation showed promise in reducing the persistence of HR-HPV after treatment, while also improving overall nutritional and metabolic health by lowering inflammation and other risk factors.
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  • * A study found that 24-hour systolic BPV showed a positive correlation with unilateral degrees of renal artery stenosis, suggesting that as stenosis increases, BPV also rises.
  • * However, no significant relationship was observed between BPV and bilateral renal artery stenosis, highlighting the need for further research on BPV and its implications in ARAS patients.
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  • The study aimed to assess the impact of Kuanxiong Aerosol (KXA) on coronary microcirculation in patients with unstable angina undergoing elective percutaneous coronary intervention (PCI).
  • Patients were divided into a trial group receiving KXA and a control group, with evaluations of coronary microcirculation resistance (IMR) and cardiac markers both before and after the procedure.
  • Results showed that the trial group had a significantly lower IMR after PCI, suggesting KXA may improve coronary microvascular dysfunction, although differences in myocardial injury rates were not statistically significant.
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  • The study aimed to assess how Weichang'an pill (WCAP) affects functional dyspepsia (FD) in rats, focusing on brain-gut peptides and gut microbiota as potential treatment mechanisms.
  • Researchers created an FD rat model and divided the rats into different treatment groups, including those receiving WCAP and a control for comparison, then measured gastrointestinal motility and gut microbiota composition.
  • Results showed that WCAP improved FD symptoms by enhancing gastric emptying, regulating brain-gut peptide levels, and restoring gut microbiota balance, suggesting it could be an effective treatment for FD.
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Simulating the multi-media fate of perfluorooctane sulfonate (PFOS) and its precursors in the Bohai coastal region of China.

Sci Total Environ

December 2024

State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China.

PFOS and its precursors are of great concern due to their persistence and widespread presence in the environment. However, few studies have been conducted on their transformation and fate at a regional scale. We aim to address this gap by investigating their fate in the Bohai coastal region of China.

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Low-temperature ethylenediamine (EDA)/urea pretreatment had been demonstrated to be an efficient pretreatment method for enzymatic hydrolysis and bioethanol production. For high-value utilization of the third main components of lignocellulosic biomass, the physicochemical structure characteristics and biological activities of low-temperature EDA/urea pretreated lignin (EUL) were comprehensively investigated in the present study. The results demonstrated that the pretreatment process facilitated the depolymerization of lignin, resulting in notable reduction in molecular weight and polydispersity index from 2.

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The differential orbitofrontal activity and connectivity between atypical and typical major depressive disorder.

Neuroimage Clin

November 2024

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Institute of Traditional Chinese Medicine, Beijing 100010, China. Electronic address:

Objective: Atypical major depressive disorder (MDD) is a distinct subtype of MDD, characterized by increased appetite and/or weight gain, excessive sleep, leaden paralysis, and interpersonal rejection sensitivity. Delineating different neural circuits associated with atypical and typical MDD would better inform clinical personalized interventions.

Methods: Using resting-state fMRI, we investigated the voxel-level regional homogeneity (ReHo) and functional connectivity (FC) in 55 patients with atypical MDD, 51 patients with typical MDD, and 49 healthy controls (HCs).

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Optimized single-bath dyeing of bio-based nylon 56/cotton blends with vat dyes: Mechanistic insights and process enhancements.

Int J Biol Macromol

January 2025

National Engineering Laboratory for Advanced Yarn and Fabric Formation and Clean Production, Technology Institute, Wuhan Textile University, Wuhan, Hubei 430200, China. Electronic address:

Nylon 56/cotton (N/C) blended fabrics have excellent durability and can cater to various clothing needs. However, the quality and value of textile garments are significantly influenced by the dyeing process. Due to variations in the structure and characteristics of nylon 56 and cotton fibers in blended fabrics, achieving consistent coloration is challenging, resulting in noticeable color discrepancies.

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Balancing Defects and Microcrystals in Carbon Anodes by Molecular Chemistry Method for Sodium-Ion Batteries.

Small

November 2024

State Key Laboratory of Chemical Resource Engineering, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China.

Article Synopsis
  • Carbon-based materials with a good balance of defects and microcrystals show potential as effective anode materials for sodium-ion batteries (SIBs), offering better capacity and conductivity.
  • The molecular chemistry technique involving cross-linking and defect repair helps manage the trade-off between active sites and conductivity limitations in these materials.
  • The resulting carbon material improves ion transfer and increases capacity significantly, from 162.5 to 336.5 mAh g, demonstrating a successful approach to enhancing SIB performance through microstructural regulation.
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The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization (WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community.

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Role of Immune Inflammation in Recurrent Spontaneous Abortions.

J Inflamm Res

November 2024

Department of Gynecology and Obstetrics, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People's Republic of China.

Objective: This study aimed to investigate the role of immune inflammation in recurrent spontaneous abortions (RSA).

Methods: In this study, decidua tissues from 12 patients were collected. These included six individuals with RSA in the RSA group and six in the control group.

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  • The study investigates the tensile properties and nanoscale phase structures of various modified asphalts, including virgin asphalt and three specific modifications, using advanced testing methods like force-ductility tests and atomic force microscopy (AFM).
  • The results indicate that while all three modified asphalts exhibit ductile fracture traits, SBS&CR asphalt requires less activation energy during stretching compared to SBS and SBS&TiO, suggesting a difference in energy efficiency during the process.
  • Furthermore, SBS&CR and SBS&TiO asphalts displayed superior tensile properties and resistance to aging, with TiO enhancing phase stability by reducing polar molecule aggregation and surface roughness while showing a more pronounced aging effect on SBS&CR asphalt.
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The traditional scoliosis examination based on X-ray film is not suitable for large-scale screening, and it is also not suitable for dynamic evaluation during rehabilitation. Therefore, based on computer vision technology, this paper puts forward an evaluation method of scoliosis with different photos of the back taken by mobile phones, which involves three aspects: first, based on the key point detection model of YOLOv8, an algorithm for judging the type of spinal coronal curvature is proposed; second, an algorithm for evaluating the coronal plane of the spine based on the key points of the human back is proposed, aiming at quantifying the deviation degree of the spine in the coronal plane; third, the measurement algorithm of trunk rotation (ATR angle) based on multi-scale automatic peak detection (AMPD) is proposed, aiming at quantifying the deviation degree of the spine in sagittal plane. The public dataset and clinical paired data (mobile phone photo and X-ray) are used to test.

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  • The study analyzed the characteristics and outcomes of COVID-19 patients during a Beijing Omicron outbreak, focusing on the impact of vaccination status on clinical severity and survival rates.
  • Data was collected from 1495 cases, showing that vaccination, especially booster shots, significantly reduced disease severity and increased survival time compared to non-vaccinated individuals.
  • Results indicated that elderly patients with pre-existing health conditions had a higher risk of severe illness and death, highlighting the importance of vaccination in this vulnerable population.
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  • - The study evaluates whether Taiwan will continue to provide coverage for nirmatrelvir/ritonavir (NMV/r) for high-risk COVID-19 patients, considering its clinical benefits and impact on healthcare resources.
  • - A decision tree model was used to compare the current utilization rates of NMV/r (80%) against a scenario where coverage is not extended (0%), leading to significant differences in hospitalizations, bed days, and mortality.
  • - The analysis suggests that continued use of NMV/r could significantly decrease healthcare-related burdens and fatalities associated with mild-to-moderate COVID-19 cases in Taiwan.
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