1,587 results match your criteria: "Behavioral Sciences Research Center[Affiliation]"

Article Synopsis
  • GABA receptors are linked to drug addiction, sleep issues, and aging, but their interrelationships are not well researched; this study focuses on how blocking these receptors influences methamphetamine (METH) reward memory in sleep-deprived rats.
  • Adult and adolescent male Wistar rats underwent seven days of rapid-eye movement sleep deprivation and then were conditioned with METH before testing their memory retrieval after administering the GABA receptor agonist baclofen.
  • Baclofen reduced METH reward memory retrieval in both age groups, with stronger effects seen in adolescents, and the high dose lowered GABA overexpression in adolescent rats, suggesting age and sleep deprivation play significant roles in addiction mechanisms.
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This methodological study aimed to assess the psychometric properties of the Persian version of the scale for evaluating self-care behaviors with arteriovenous fistula. This cross-sectional study with a methodological design was planned and conducted in 2022. The Scale of the Assessment of Self-Care Behaviors with Arteriovenous Fistula was translated into Persian.

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Article Synopsis
  • - Social anxiety disorder (SAD), or social phobia, is a common psychiatric condition marked by intense fear of social situations, often co-occurring with depression and substance abuse issues.
  • - Despite its prevalence, effective management of SAD can be hindered when doctors focus on related mental health complications instead of the disorder itself.
  • - The study examines how serotonin influences the development of SAD and discusses potential treatment strategies targeting serotonin metabolism, although the underlying mechanisms and treatment effectiveness remain unclear.
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Objective: The purpose of the present study was to design the Farsi Scale of Sexual-Reproductive Needs and Concerns of never-married women over 35 and to assess its psychometric properties.

Materials And Methods: This mixed method research had two phases. The first phase was qualitative (Conventional Content Analysis).

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Article Synopsis
  • Tuberculosis, particularly smear-positive pulmonary tuberculosis (SPPTB), is a significant public health concern in Iran, necessitating an analysis of its effective reproduction number and patient demographics from 2011 to 2021 to inform control strategies.
  • A historical cohort study found that while SPPTB cases declined overall, a significant portion of patients faced delays in diagnosis, and there were notable differences in transmission rates across provinces, with certain areas showing higher effective reproduction numbers.
  • Despite a general decrease in effective reproduction numbers from 2011 to 2020, a rise was noted post-COVID-19, stressing the importance of targeted health interventions in regions with persistent high incidence rates.
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Introduction: Hand hygiene in nurses is the most effective factor in controlling nosocomial infections. The objective of this study was to assess the effectiveness of motivational interviews and teach-back on the rate of hand hygiene compliance in Intensive Care Unit nurses.

Methods: A quasi-experimental study with pre-test and post-test design was performed.

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Electrochemical biosensors in early detection of Parkinson disease.

Clin Chim Acta

January 2025

Psychiatry and Behavioral Sciences Research Center, Addiction Institute, and Department of Psychiatry, School of Medicine, Mazandaran University of Medical Sciences, Sari,Iran. Electronic address:

Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting the motor system, with symptoms including tremors, rigidity, bradykinesia, and postural instability. Affecting over six million people globally, PD's pathophysiology is marked by the loss of dopaminergic neurons in the substantia nigra. Early diagnosis is crucial for effective management, yet current methods are limited by low sensitivity, high cost, and the need for advanced equipment.

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Article Synopsis
  • Polyps are a common issue for women, leading to symptoms like bleeding and infertility, and they may develop into more serious conditions.
  • A study in Isfahan analyzed 1004 patients who underwent hysteroscopic polypectomy, revealing a 63.8% improvement in symptoms but a 14.2% recurrence rate.
  • The findings suggest that hysteroscopic polypectomy is highly effective with few complications, and using scissors for the procedure reduces the chance of recurrence compared to using graspers.
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Childhood maltreatment, alexithymia and impulsivity are related to bipolar disorder (BD), but the role of potential underlying mechanisms of this link, such as extreme sensory processing, in BD are unclear. This study compared sensory processing patterns between individuals with BD-I or BD-II and between those with and without alexithymia and childhood maltreatment. Additionally, the study aimed to examine the role of extreme sensory processing in the relationship between childhood trauma, alexithymia and impulsivity with both depression and mania in a sample of hospitalized individuals with BD (n = 300).

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Article Synopsis
  • Major psychotic disorders like schizophrenia and schizoaffective disorder have unclear causes, but recent studies indicate that inflammation and immune factors, specifically Interleukin 17 (IL-17), may play a role.
  • A case-control study involving 101 participants showed significantly higher serum levels of IL-17 A and CCL20 in major psychotic disorder patients compared to healthy controls, correlating with the severity of the disorders.
  • The findings suggest that measuring IL-17 A and CCL20 could help in understanding the pathology of major psychotic disorders and inform diagnosis and treatment strategies.
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Sepsis is associated with brain injury and acute brain inflammation, which can potentially transition into chronic inflammation, triggering a cascade of inflammatory responses that may lead to neurological disorders. Minocycline, recognized for its potent anti-inflammatory properties, was investigated in this study for its protective effects against sepsis-induced brain injury. Adult male C57 mice pretreated with minocycline (12.

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Article Synopsis
  • The study focused on the importance of managing bleeding during nose surgery (rhinoplasty) to minimize surgical complications and improve visibility for surgeons.
  • In a double-blind clinical trial involving 98 patients, researchers compared the effects of two substances—tranexamic acid and phenylephrine—on bleeding during the procedure.
  • Results indicated that the phenylephrine group experienced significantly less bleeding compared to the tranexamic acid group, suggesting phenylephrine is better for reducing bleeding in rhinoplasty.
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Background: Postpartum depression is a major psychiatric disorder that affects the mother-baby attachment and may impair cognitive development of the child.

Objective: This study aimed to evaluate the effect of curcumax (including ginger, turmeric, and black pepper) on postpartum depression in reproductive-aged women.

Material And Methods: This was a randomized controlled trial in which 124 women were recruited and randomly assigned into two groups of curcumax (n=62) and placebo (n=62) who consumed curcumax or placebo for 8 weeks (one capsule each day).

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Cerebral ischemia has the highest global rate of morbidity and mortality. It occurs when a sudden occlusion develops in the arterial system, and consequently some parts of the brain are deprived from glucose and oxygen due to the cessation of blood flow. The ensuing reperfusion of the ischemic area results in a cascade of pathological alternations like neuronal apoptosis by producing excessive reactive oxygen species (ROS), oxidative stress and neuroinflammation.

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Background: Caring for COVID-19 patients has caused high stress and burnses. Therefore, the current research aims to develop and validate an educational-therapeutic package based on psychological flexibility for COVID-19 nurses.

Materials And Methods: The approach of this research was Exploratory Sequential Mixed Method, which was carried out in 2019 to 2021.

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Background And Aims: Overweight and obesity are on the rise worldwide and may affect female sexual function. The aim of this study was to investigate the relationship between sexual function in normal and overweight pregnant women with gestational diabetes mellitus (GDM).

Methods: This cross-sectional study was conducted in overweight and normal-weight pregnant women with GDM in Sari, Iran.

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Article Synopsis
  • - This study investigates the challenges faced in nursing education in Iran by examining the experiences of nursing tutors to enhance the quality of nursing care.
  • - Conducted over nine months with 18 experienced tutors, the research collected data through interviews and observations, ultimately employing a grounded theory approach to analyze and categorize the educational challenges.
  • - The findings identified three main categories of challenges in nursing education and emphasized the importance of need-based education, focusing on improving tutor skills, managing educational settings, and encouraging student engagement.
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Background: women post-menopause, are faced with various physical, emotional, and relational challenges. One such aspect that tends to be overlooked is the impact of menopause on sexual well-being. This study aimed to elucidate the concept of enriching the sexual life of women post-menopause.

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Background: Paying attention to palliative care has accelerated in Iran in the last 10 years. Considering the trend of aging, increasing burden of chronic diseases and increasing health costs, planning and development of palliative care is necessary in the future. This study was conducted with the aim of explaining the alternative scenarios of palliative care in the health system of Iran until the horizon of 2030.

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Introduction: Evidence declared lipopolysaccharide (LPS) initiates inflammatory responses by stimulating the abandon of cytokines, which may perturb organ function. On the other side, it has been suggested Cedrol has potential properties, including anti-inflammatory and anti-oxidative activities. Herein, this study was done to assess the protective effect of Cedrol against LPS-associated heart damage.

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The Relationship Between Iron and Zinc Deficiency and Aphthous Stomatitis: A Systematic Review and Meta-Analysis.

Adv Biomed Res

April 2024

Department of Epidemiology and Biostatistics, School of Health, Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Article Synopsis
  • Recurrent aphthous stomatitis (RAS) is a common oral ulcer condition with unknown causes, and this study explores how iron and zinc deficiencies may relate to its occurrence.
  • The systematic review included 22 studies out of an initial 1,383, using databases and specific criteria to ensure quality and relevance.
  • The results showed that patients with RAS had significantly lower levels of serum iron and zinc compared to healthy individuals, indicating a potential link between these deficiencies and the disease.
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Can infliximab serve as a new therapy for neuropsychiatric symptoms?

Naunyn Schmiedebergs Arch Pharmacol

September 2024

Electrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.

Article Synopsis
  • * Tumor necrosis factor alpha (TNFα) is an inflammatory substance that plays a role in these disorders, making its inhibition a relevant target for treatment.
  • * Infliximab, a medication used for inflammatory conditions, has shown promise in improving issues like cognitive dysfunction, depression, and anxiety, suggesting it could be an effective option for treating neuropsychiatric disorders. *
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