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Background: African animal trypanosomosis (AAT) is one of the most serious diseases with ongoing detrimental effects on animal health and food production.

Methods: A cross-sectional study was conducted in the Bedele and Dedesa districts of Buno Bedele Zone, Southwest Ethiopia, to determine the prevalence of trypanosomosis and its vector distributions in small ruminants. Blood samples collected from a total of 384 small ruminants were examined for trypanosomosis via hematological analysis.

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