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The prevalence of , a pathogen, has decreased globally in the last decade. To date, the management of has focused on a reactive approach, whereby those diagnosed are treated with antimicrobials and acid suppression in combination. This review article provides an overview of the shift in the management of from a reactive approach towards a proactive 'screen and treat' approach; the article reflects the current pharmacological landscape for treatment by exploring similarities such as the first-line prescription of quadruple therapy in most countries and provides a summary table of the best practice guidance from Europe, Asia, and North America.

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