Case of a Man with Hemichorea and Behavioral Changes: "A Red Herring".

Background: Progressive supranuclear palsy (PSP)-pallido-nigro-luysian atrophy (PNLA) is a neuropathological entity thought to be a variant of classic PSP. Clinical features and pathologic hallmarks are the same in both conditions; however, age and order of symptom onset, disease duration and prognosis, and distribution and density of pathology differentiate the 2 entities.

Objectives: This study presents a PSP-PNLA case confirmed pathologically with a clinical presentation of hemichorea/ballism, spasticity, progressive hemiparesis, and a frontal behavioral syndrome with relative cognitive sparing early in the disease course.

Development and evaluation of a self-administered on-line test of memory and attention for middle-aged and older adults.

There is a need for rapid and reliable Internet-based screening tools for cognitive assessment in middle-aged and older adults. We report the psychometric properties of an on-line tool designed to screen for cognitive deficits that require further investigation. The tool is composed of measures of memory and executive attention processes known to be sensitive to brain changes associated with aging and with cognitive disorders that become more prevalent with age.

Effects of age-related hearing loss and background noise on neuromagnetic activity from auditory cortex.

Aging is often accompanied by hearing loss, which impacts how sounds are processed and represented along the ascending auditory pathways and within the auditory cortices. Here, we assess the impact of mild binaural hearing loss on the older adults' ability to both process complex sounds embedded in noise and to segregate a mistuned harmonic in an otherwise periodic stimulus. We measured auditory evoked fields (AEFs) using magnetoencephalography while participants were presented with complex tones that had either all harmonics in tune or had the third harmonic mistuned by 4 or 16% of its original value.

Brain signal variability as a window into the bidirectionality between music and language processing: moving from a linear to a nonlinear model.

There is convincing empirical evidence for bidirectional transfer between music and language, such that experience in either domain can improve mental processes required by the other. This music-language relationship has been studied using linear models (e.g.

Attention and visuospatial working memory share the same processing resources.

Attention and visuospatial working memory (VWM) share very similar characteristics; both have the same upper bound of about four items in capacity and they recruit overlapping brain regions. We examined whether both attention and VWM share the same processing resources using a novel dual-task costs approach based on a load-varying dual-task technique. With sufficiently large loads on attention and VWM, considerable interference between the two processes was observed.

Dissociable memory- and response-related activity in parietal cortex during auditory spatial working memory.

Attending and responding to sound location generates increased activity in parietal cortex which may index auditory spatial working memory and/or goal-directed action. Here, we used an n-back task (Experiment 1) and an adaptation paradigm (Experiment 2) to distinguish memory-related activity from that associated with goal-directed action. In Experiment 1, participants indicated, in separate blocks of trials, whether the incoming stimulus was presented at the same location as in the previous trial (1-back) or two trials ago (2-back).

Exploring the recognition memory deficit in Parkinson's disease: estimates of recollection versus familiarity.

Current theories postulate that recognition memory can be supported by two independent processes: recollection (i.e. vivid memory for an item and the contextual details surrounding it) versus familiarity (i.

A Collaborative Approach to Workforce Transformation: Food and Nutrition Services Staff Education.

Recent health care system changes have required the food and nutrition services workforce to learn new job skills, and to work with significantly less supervision. At Baycrest Centre for Geriatric Care (892 beds), the Food and Nutrition and the Education and Organizational Development Departments collaborated to budget for, plan, and implement an educational program to transform a traditional food service workforce into an effective self-managing team. The workforce actively participated in a needs assessment process to identify the skills and behaviours requiring change.