933 results match your criteria: "Baskent University İstanbul Research Hospital[Affiliation]"

Article Synopsis
  • - The study investigates how spinal stabilization exercises affect functional exercise capacity in individuals with transtibial amputation, comparing these exercises with a conventional physiotherapy program over an 8-week period.
  • - Results showed significant improvements in functional exercise capacity, step count, and deep spinal muscle strength for the group that included spinal stabilization exercises, compared to the control group.
  • - The findings suggest that integrating spinal stabilization exercises into rehabilitation could enhance physical capacity and mobility in amputees, highlighting the importance of targeted exercise programs.
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  • Epilepsy is a common chronic brain disease with genetic roots, and this study aims to analyze facial measurements in both epilepsy patients and healthy individuals to find characteristics that might influence epilepsy diagnosis.
  • The research included 120 epilepsy subjects and 60 healthy controls, measuring different facial angles and lengths using CT scans to compare the two groups.
  • The results indicated specific facial measurements were significantly different in epilepsy patients, suggesting that epilepsy may influence certain facial features, though no age-related changes were observed in healthy subjects.
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Hypertensive disorders of pregnancy are significant contributors to maternal and perinatal morbidity and mortality. The definition, classification, and management of these disorders have evolved over time. Notably, the disease classification enables caretakers to manage the disease as well as safeguard maternal and fetal health.

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Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP).

Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed.

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  • Sodium-glucose cotransporter-2 inhibitors (SGLT2i) help lower blood glucose and sodium levels by promoting their excretion in urine, leading to benefits like reduced heart failure (HF) hospitalizations in patients with type 2 diabetes (T2DM) and cardiovascular (CV) risks.
  • Clinical trials like DAPA-HF and EMPEROR-Reduced demonstrate that SGLT2i medications (dapagliflozin and empagliflozin) significantly reduce CV mortality and HF hospitalizations in heart failure patients, whether they have T2DM or not.
  • Recent studies, including EMPEROR-Preserved and DELIVER, also support the effectiveness of SGLT2is in treating heart
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Objective: Unicornuate uterus, which is a rare congenital anomaly, has been associated with obstetric and perinatal complications. The aim of this study is to evaluate the reproductive outcomes of patients with unicornuate uterus, and also to compare them with outcomes of infertile patients without a Müllerian anomaly.

Methods: Retrospective analyses of the data of 18-40 year old infertile patients with unicornuate uterus diagnosed in between January 2012 and December 2022, and a control group with the same number of patients, with age and infertility durations matched were performed.

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This study aims to investigate the effects of a neurofeedback system on cognitive skills, as measured by the Wechsler Intelligence Scale for Children-Revised (WISC-R), in a cohort of 100 children aged 8 to 12 who were diagnosed with attention deficit. A randomized single-blind sham control group design was employed, with 50 participants assigned to the experimental group receiving neurofeedback training and 50 participants assigned to the sham group receiving simulated training. Participants were selected through random sampling from individuals seeking assistance at a specialized education center over the course of one year (May 2021-2022).

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  • Post-COVID interstitial lung disease (ILD) is a condition affecting COVID-19 survivors, characterized by persistent respiratory symptoms and lung function abnormalities, often identified through CT scans.
  • A study analyzed data from 375 patients who experienced lingering symptoms three months after recovering from COVID-19, finding that 262 of them (about 70%) had post-COVID ILD, with common symptoms including shortness of breath, exercise intolerance, fatigue, and cough.
  • Risk factors for developing post-COVID ILD included active smoking and having been admitted to intensive care during the acute phase of the disease; typical CT findings included ground glass opacities and fibrotic changes, indicating lung damage.
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Objective: Primary hypophysitis might be challenging to diagnose, and there is a lack of evidence regarding optimal treatment strategies due to rarity of the disease. We aim to investigate the clinical features and compare the outcomes of different management strategies of primary hypophysitis in a large group of patients recruited on a nationwide basis.

Design: A retrospective observational study.

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Introduction: Patients with airway diseases who bear the burden of smoking need access to smoking cessation support. We aimed to investigate the impact of immediately scheduled appointments on access to smoking cessation clinics compared with usual care in this patient group.

Methods: This multicenter, prospective, randomized, open-label study was conducted between November 2022 and June 2023 at pulmonary outpatient clinics.

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Objective: Laparoscopic hysterectomy has become an increasingly used surgery in recent years. The aim of this study was to evaluate the clinical features and perioperative outcomes of patients who underwent laparoscopic hysterectomy for benign or malignant indications in a single center during a period of eight years.

Material And Methods: Data of patients who underwent laparoscopic hysterectomy in the gynecological oncology department of a university hospital over a period of eight years was analyzed retrospectively.

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  • Latent tuberculosis infection (LTBI) screening is essential for solid organ transplant (SOT) recipients, but many centers in Turkey are not adequately performing these screenings.
  • In a study involving 766 SOT patients, 46.9% tested positive for LTBI, but only about half of those treated were registered, and there was a low completion rate of treatment.
  • The findings highlight the need for better TB risk assessment and adherence to national guidelines to improve pre-transplant care for SOT recipients in Turkey.
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Background/aims:  Although hepatocellular carcinoma (HCC) usually develops in cirrhotic livers, HCCs could also arise in non-cirrhotic livers. We aimed to compare the characteristics and survival of cirrhotic- and non-cirrhotic HCCs.

Materials And Methods:  Data of HCC patients between 2011 and 2021 in a single tertiary center was evaluated retrospectively.

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This study aimed to determine the effectiveness of extracorporeal shockwave lithotripsy (SWL) performed in the early period (within the first 24 hours). Data of patients who underwent SWL with a diagnosis of unilateral radiopaque 5 to 10 mm upper ureteral stones were retrospectively examined. Patients were divided into 2 groups.

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Background: Premenstrual syndrome (PMS) is characterized by physical, cognitive, emotional, and behavioral symptoms that appear during the luteal phase of the menstrual cycle, disappear after menstruation, and are recurrent in every cycle. PMS significantly affects the social and academic lives of adolescents, and historically, it has been neglected by healthcare professionals. We aimed to evaluate the current point prevalence of PMS in Turkish adolescents presented to a tertiary adolescent medicine clinic.

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Article Synopsis
  • This study focuses on 17α Hydroxylase/17,20 Lyase Deficiency (17OHD), a rare form of adrenal hyperplasia, highlighting its clinical features such as delayed puberty and hypertension commonly diagnosed in late adolescence.
  • Researchers analyzed data from 97 cases across the country, revealing that hypertension was present in 65% and hypokalemia in 34% of patients, with a significant number requiring antihypertensive treatment.
  • The findings suggest that early diagnosis can be guided by hypertension and hypokalemia, while the final heights of patients generally fall within normal ranges, though the connection between genetic mutations and clinical outcomes remains unclear.
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  • This study aimed to compare childhood-onset schizophrenia (COS) and early-onset schizophrenia (EOS) in terms of clinical characteristics, treatment approaches, and factors influencing prognosis.
  • It involved analyzing data from 31 COS and 66 EOS patients, assessing their symptoms and treatment effectiveness using established scales during both acute and stable phases.
  • Significant differences were found in treatment outcomes and symptom severity between the two groups, with COS patients showing higher comorbidities and requiring more complex treatments, highlighting the need for early diagnosis and specific predictors for better management of schizophrenia.
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Objective: Heart failure is a leading cause of death and the most common diagnosis leading to hospitalization. Its awareness is lower than that of other cardiovascular diseases, both in the general population and among patients with heart failure (HF). This study aimed to establish the current level of knowledge about HF in patients with HF with reduced ejection fraction (HFrEF) and mildly reduced ejection fraction (HFmrEF) in Türkiye.

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Comparison of two methods for treatment of 1-2 cm kidney stones in pediatric patients: mini PCNL and RIRS.

Langenbecks Arch Surg

July 2024

Department of Urology, Adana City Training and Research Hospital, Health Sciences University, Adana, Türkiye.

Objective: This study aimed to compare the results of retrograde intrarenal surgery (RIRS) and mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of 1-2 cm kidney stones in pediatric patients.

Methods: The records of patients under the age of 18 years who were diagnosed with unilateral 1-2 cm kidney stones for the first time and underwent endoscopic surgery between February 2008 and April 2022 were retrospectively examined. The patients were divided into two groups: mini-PCNL and RIRS surgery.

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Objectives: We explored the prognostic utility of the unique combination of C-reactive-protein-to-albumin ratio (CAR) and significant weight loss (WL > 5%) over the preceding 6 months, namely, the CARWL score, in stage IIIC non-small-cell lung cancer (NSCLC) patients who underwent concurrent chemoradiotherapy (CCRT).

Methods: For each patient, the CAR was calculated using C-reactive protein and albumin measurements obtained on the first day of CCRT: CAR = C-reactive protein ÷ albumin. The availability of an ideal CAR cutoff that may categorize patients into two distinct progression-free (PFS) and overall survival (OS) outcomes was explored by employing receiver operating characteristic (ROC) curve analysis.

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Introduction: This study purpose of determining the short-term effects of kinesio taping on drooling in children with cerebral palsy (CP).

Methods: CP were randomly divided into 3 groups as the kinesio tape ( = 16), sham tape ( = 16), and control ( = 16) groups. The drooling severity and frequency were assessed with the Drooling Severity and Frequency Scale, and the amount of saliva was measured by the 5-minute drooling quotient.

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Cytokine expression profiles in children and adolescents with tic disorders.

Sci Rep

July 2024

Faculty of Engineering and Natural Sciences, Molecular Biology, Genetics and Bioengineering Program, Sabanci University, 34956, Tuzla, Istanbul, Turkey.

The etiology of tic disorders (TDs) is not precisely known, although several lines of evidence suggest involvement of the immune system in pathogenesis. Here, we aimed to determine the expression levels of pro-inflammatory and anti-inflammatory cytokines in children with TD and compare them with those of healthy controls. Furthermore, we also evaluated their association with clinical variables in the TD group.

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Article Synopsis
  • * A study conducted whole-exome sequencing (WES) on 303 IEI patients in Türkiye, achieving likely genetic diagnoses for 41.1% and discovering 52 novel variants, as well as new potential IEI genes in six patients.
  • * The findings emphasize the importance of cross-cohort outcomes in IEI research and aim to enhance collaboration between clinical and scientific communities.
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Background: This study aimed to provide nuanced insights in managing patients with a history of coronavirus disease 2019 (COVID-19) pneumonia undergoing coronary artery bypass grafting.

Methods: This retrospective cohort study involved 168 patients (131 males, 37 females; mean age: 61.2±9.

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