1,264 results match your criteria: "Basilar Artery Thrombosis"

Stents are increasingly used for coiling difficult aneurysms, to reduce the risk of recurrences, or to modify blood flow. Currently, available bifurcation aneurysm models are ill-suited to assess stent performance before clinical use. We designed a new animal model of wide-neck canine Y-type bifurcation aneurysm (such as middle cerebral artery (MCA) bifurcation) and previously reported one of T-type (such as basilar bifurcation).

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  • Basilar artery strokes are hard to diagnose due to their varied symptoms, but quick identification is crucial to prevent serious issues.
  • A 28-year-old woman was admitted after experiencing convulsive activity and confusion, which led to a diagnosis of nonocclusive basilar artery thrombosis and additional strokes from imaging tests.
  • Her recent preeclampsia highlights the importance of recognizing pregnancy-related stroke risks and the need for prompt imaging to improve outcomes in such cases.
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  • Managing giant partially thrombosed intracranial aneurysms is challenging due to high recurrence rates and a lack of standardized treatment methods.
  • A case study of a 62-year-old man with a giant aneurysm at the basilar artery received successful two-stage endovascular treatment, including a balloon occlusion test and stent-assisted WEB embolization.
  • Post-treatment, imaging confirmed no recanalization, and the patient had stable recovery with no neurological deficits after 12 months, showcasing the effectiveness of this advanced treatment approach.
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  • Antiphospholipid syndrome (APS) is a rare autoimmune disorder in children that can result in thrombosis, characterized by the presence of specific antibodies.
  • A six-year-old girl was diagnosed with hemolytic anemia and later developed neurological and cardiovascular issues, revealing APS, which manifested with intravascular hemolysis and coagulation abnormalities.
  • After comprehensive treatment involving immunoglobulins and glucocorticoids, the patient's condition significantly improved, highlighting the importance of recognizing APS in pediatric cases.
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  • Vertebral artery dissection (VAD) is a rare but serious condition caused by tearing in the vertebral artery, leading to symptoms like headache and dizziness, and requires timely diagnosis for better outcomes.
  • A young male patient experienced severe headache and seizures, and imaging revealed bilateral VAD and complications like brainstem infarcts, but digital subtraction angiography missed the dissection.
  • High-resolution magnetic resonance imaging (HRMRI) successfully confirmed the diagnosis of VAD and supported the patient's treatment plan, ultimately leading to significant recovery after rehabilitation.*
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  • - The study focuses on the rise of invasive fungal sinusitis, particularly mucormycosis, in post-COVID-19 patients in India, highlighting the importance of early diagnosis through neuroimaging to improve survival rates.
  • - Researchers analyzed MR imaging from 91 confirmed cases, finding that over half of the patients (51.6%) had advanced disease with intracranial spread, with significant complications such as cavernous sinus involvement and osteomyelitis.
  • - The results showed that unlike non-COVID-19 cases, there were no instances of certain severe complications like thrombosis in the studied COVID-19-associated cases, emphasizing unique patterns in disease manifestation.
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  • Giant thrombosed posterior circulation aneurysms are rare but can lead to severe complications, with treatment options involving high risks of recurrence and complications.
  • A 47-year-old woman underwent microsurgical clipping for a right giant thrombosed basilar artery-superior cerebellar artery aneurysm, utilizing double protective bypass techniques to reduce the risk of complications.
  • The patient initially faced some recovery challenges but ultimately showed significant improvement with no deficits after 6 months, highlighting the effectiveness of protective bypasses in such surgical interventions.
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Repeated basilar tip occlusion associated with atlantooccipital assimilation: A case report.

J Stroke Cerebrovasc Dis

December 2024

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan; Department of Neurosurgery, Tokyo General Hospital, Tokyo, Japan.

Article Synopsis
  • An 82-year-old man experienced multiple strokes caused by vertebral artery dissection linked to a condition called atlanto-occipital assimilation.
  • Despite attempts to treat him with thrombectomy and medication changes, he suffered from recurring strokes due to damage to the vertebral artery and abnormal neck movements.
  • This case emphasizes the rare connection between atlanto-occipital assimilation and strokes, underlining the need to consider structural issues in stroke treatment.
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  • A healthily 37-year-old male experienced BAO symptoms just 30 minutes after the onset, following a recent COVID-19 vaccination, and underwent two mechanical thrombectomy procedures within 24 hours due to reocclusion.
  • The patient showed significant improvement after repeated treatments, leaving the hospital with a low NIHSS score, indicating good recovery potential following rehabilitation.
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  • Crossing Y-stent-assisted coiling (CYSAC) is a promising method for treating challenging wide-neck bifurcation aneurysms, although it can be technically difficult.
  • A study involving 37 patients treated with Y-stent-assisted coiling using LVIS EVO stents showed that a significant majority (83.8%) achieved excellent occlusion immediately after treatment, with high success rates maintained over an average follow-up of nearly 33 months.
  • The researchers' "drill turn" technique for stent crossing was effective, leading to safe outcomes and stable occlusion rates, demonstrating the method's feasibility for treating these aneurysms.
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Facial Colliculus and Sixth Nerve Nuclear Infarct as a Sentinel Sign of a Thrombosed Basilar Artery Aneurysm.

J Neuroophthalmol

September 2024

Department of Neurology (LB, JK), University of Illinois COM Peoria, Peoria, Illinois; Department of Neurology (LB, JK), OSF Illinois Neurological Institute, Peoria, Illinois; and College of Medicine (AH), St. George's University, True Blue, Grenada.

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  • Thromboembolic (TE) events, which can arise even with proper dual antiplatelet therapy, are serious complications following flow diversion (FD) procedures used to treat aneurysms, leading to significant morbidity and mortality.
  • A study was conducted on 651 FD procedures in 591 patients from 2013 to 2023, revealing a TE event rate of 5.8%, with permanent deficits in 20 patients and 4 fatalities linked to vascular occlusions.
  • Factors such as aspirin resistance, age, and aneurysm characteristics were identified as predictors for the occurrence of TE events, particularly highlighting the high morbidity associated with large-vessel occlusions in the middle cerebral artery.
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  • The Contour Neurovascular System (CNS) is a new device designed to treat intracranial aneurysms by disrupting blood flow within the aneurysm sac, focusing on cases where previous treatments have failed.
  • In a study involving ten patients with recurring aneurysms, various factors such as technical success, complications, and angiographic outcomes were evaluated, revealing no serious complications during the procedure.
  • Results showed a 50% complete occlusion rate of aneurysms at follow-up, indicating that the CNS could be effective, especially for certain aneurysm shapes; however, more research is needed to determine which types of aneurysms benefit most from this treatment.
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  • The study investigates the Thrombus Enhancement Sign (TES) in patients with basilar artery occlusion undergoing endovascular treatment, aiming to understand its connection to stroke subtype and recanalization success.
  • Among 151 patients, 77% were TES-positive, showing strong associations with cardioembolic and cryptogenic strokes, as well as distinct thrombus composition.
  • TES-positive patients experienced better outcomes, such as faster procedure times and higher recanalization success rates, with TES being a significant predictor of successful treatment outcomes.
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  • - The case describes a patient with untreated hypertension exhibiting symptoms consistent with Wallenberg syndrome, such as dizziness, vomiting, and altered consciousness, emphasizing the importance of recognizing these symptoms early.
  • - Comprehensive assessments, including MRI and MRA, revealed ischemic lesions caused by basilar artery thrombosis related to the patient's hypertension, highlighting the critical role of imaging in diagnosing cerebrovascular conditions.
  • - The patient's lack of treatment for hypertension and related risks underlines the necessity for proactive patient care and risk factor management to prevent serious complications like cerebral artery thrombosis.
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  • Flow diversion treatment for bifurcation aneurysms raises concerns about ischemic events, particularly when covering the posterior cerebral artery (PCA) during the procedure.
  • A study analyzed 28 patients with basilar and proximal PCA aneurysms over 10 years, finding that exclusion of the PCA occurred in 15 cases, with an 80.8% success rate in occluding the aneurysms.
  • Despite some patients experiencing thromboembolic complications, the occurrence was not significantly higher in those where the PCA was covered, and there was no notable difference in post-treatment disability between the two groups.
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  • * An 80-year-old patient with an enlarging aneurysm affecting her sixth cranial nerve was found to have anatomical challenges that ruled out traditional endovascular options like transradial or transfemoral access.
  • * This case highlights a new combined approach using microsurgery for accessing the vertebral artery, allowing for effective treatment of complex aneurysms when standard methods are too risky.
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  • Basilar artery occlusion (BAO) can result from either embolism or thrombosis due to basilar stenosis, with the latter (BAOS) leading to worse clinical outcomes compared to embolic occlusions (BAOE).
  • A study involving 199 patients found that specific brain regions, particularly the medulla oblongata and inferior pons, played a critical role in predicting unfavorable early outcomes after BAO, with BAOS patients having larger infarct volumes.
  • Successful reperfusion was more common in BAOE patients, indicating that differences in occlusion type and brain stem infarct patterns significantly impact recovery and outcomes after treatment.
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  • - The study investigates the effectiveness of anticoagulant treatments for nonocclusive thrombi in patients with acute ischemic stroke or transient ischemic attack, revealing that both unfractionated and low molecular weight heparin were used on 52 patients diagnosed via CT angiography.
  • - Results showed that 96% of patients achieved complete thrombus resolution within two weeks, with cervical segment internal carotid arteries being the most affected; common underlying conditions included atherosclerosis and atrial fibrillation.
  • - Importantly, no major bleeding complications arose from anticoagulant use, leading to favorable functional outcomes post-treatment as assessed by the modified Rankin scale.
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  • Standalone coil embolization is often ineffective for partially thrombosed intracerebral aneurysms (PTIA) due to risks of recurrence if coils migrate into the thrombus.
  • A 63-year-old male with a history of a basilar artery aneurysm underwent successful coil embolization using a Target 3D Coil, leading to complete disappearance of the aneurysm and improved nerve function after five years.
  • The design of the Target 3D Coil likely prevented migration into the thrombus, aiding in the successful resolution of the aneurysm.
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  • * The echocardiogram identified significant heart defects, including an interrupted aortic arch and a large ventricular septal defect, but the presence of a patent ductus arteriosus prevented immediate complications from this reversed flow.
  • * Ultimately, the infant was diagnosed with DiGeorge syndrome, underwent corrective surgery for the interrupted aortic arch, and restored normal blood flow in the basilar artery, highlighting the critical nature of recognizing these congenital vascular anomalies.
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IV Thrombolysis in Basilar Artery Occlusion: Outcomes and Comparison With Endovascular Thrombectomy.

Neurology

April 2024

From the Departments of Neurology (S.R., J.R., T.S., P.J.L., D.S.) and Radiology (P.V.), Helsinki University Hospital and University of Helsinki, Finland; Department of Clinical Therapeutics (G.G.), National and Kapodistrian University of Athens, Greece; School of Biomedical Engineering and Imaging Sciences (G.G.), King's College London; and Institute of Cardiovascular Science (G.G.), University College London, United Kingdom.

Article Synopsis
  • - The study examines the outcomes of intravenous thrombolysis (IVT) in patients with basilar artery occlusion (BAO) and compares it to endovascular thrombectomy (EVT), noting that IVT has often been underrepresented in prior studies despite being effective beyond the usual treatment window.
  • - Data from a cohort of 376 patients treated between 1995-2022 reveals that 65.2% received only IVT, with about 46.5% achieving favorable outcomes at 3 months, although there was a notable mortality rate of 35.9%.
  • - Factors like younger age and less severe symptoms were linked to better outcomes for those treated solely with IVT, and the research used advanced
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Basilar artery perforator aneurysms: a comparison with non-perforator saccular aneurysms.

Acta Neurochir (Wien)

March 2024

Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD, UK.

Article Synopsis
  • - The study investigates basilar artery perforator aneurysms (BAPAs), which are rare compared to regular aneurysms, focusing on their presentation, imaging features, and outcomes.
  • - Researchers analyzed cases of BAPAs from a neurovascular database and found that out of 739 patients with subarachnoid hemorrhage, 9 had BAPAs, which were more common in males but showed similar severity to non-perforator aneurysms.
  • - Most BAPAs were initially missed on CT angiography, but showed significant enhancement on vessel wall imaging; the majority spontaneously thrombosed with conservative management, leading to no complications or rebleeds.
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