1 results match your criteria: "Basic Medicine Department of North China Coal Medical College[Affiliation]"
[Effect of edaravone on extracellular signal-regulated kinase 1/2 pathway following severe traumatic brain injury in rats].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
April 2010
Basic Medicine Department of North China Coal Medical College, Tangshan 063000, Hebei, China.
Article Synopsis
- The study investigates the protective effects of edaravone on severe traumatic brain injury (TBI) in rats, aiming to understand its underlying mechanisms.
- Two hundred and seventy-three male rats were divided into four groups: control, model (TBI), low-dose, and high-dose edaravone treatment, with various assessments made on brain tissue damage and neuron apoptosis over time.
- Results indicated that edaravone treatment reduced neuronal damage, apoptosis, and improved learning and memory function compared to untreated TBI rats, suggesting a therapeutic potential for edaravone in TBI recovery.