3 results match your criteria: "Basic Medical College of Gannan Medical University[Affiliation]"

Article Synopsis
  • Antiviral innate immunity is driven by type I interferon (IFN-I) and interferon-stimulated genes (ISGs), with regulation influenced by various factors and signaling adaptors.
  • Ubiquitination, a common posttranslational modification, plays a key role in controlling the antiviral signaling pathway, primarily through the action of E3 ubiquitin ligases.
  • Understanding these regulatory mechanisms can help researchers discover new therapeutic targets for viral infections, and the text focuses on identifying a specific RING Finger family protein that modulates the RIG-I-mediated IFN-I pathway via ubiquitination.
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Objective: The purpose of this systematic review was to explore the value of the expression level of the triggering receptor expressed on myeloid cell-1 (TREM-1) in the diagnosis and prognosis of neonatal sepsis.

Methods: A comprehensive search was performed to identify the diagnostic and prognostic predictive values of the TREM-1 expression level in neonatal sepsis. Based on the retrieval strategy, Cochrane Library, Embase, Ovid, ProQuest, PubMed, Scopus, and Web of Science databases were searched from inception to February 2022.

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Innate Immune Evasion by Human Respiratory Syncytial Virus.

Front Microbiol

March 2022

Neonatal/Pediatric Intensive Care Unit, Children's Medical Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Respiratory syncytial virus (RSV) is the leading cause of severe respiratory infection in young children. Nearly all individuals become infected in their early childhood, and reinfections with RSV are common throughout life. Primary infection with RSV is usually involved in the symptom of bronchiolitis and pneumonia in the lower respiratory tract, which accounts for over 3 million hospitalizations and approximately 66,000 deaths annually worldwide.

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