5 results match your criteria: "Basel University Hospital and Basel University[Affiliation]"
Structured diagnostic assessment of hand eczema in cleaning workers.
J Dtsch Dermatol Ges
May 2021
Dermatology, Basel University Hospital and Basel University, Basel, Switzerland.
Hand dermatitis is a widespread problem among cleaners. In most cases, it is caused by a combination of wet work and contact with irritants, which can result in irritant (toxic) contact dermatitis. In some cases, the irritant contact eczema then evolves into allergic contact dermatitis, although not all cases of allergic contact dermatitis are preceded by irritant contact dermatitis.
View Article and Find Full Text PDFUse of acoustic cardiography immediately following electrical cardioversion to predict relapse of atrial fibrillation.
J Atr Fibrillation
June 2017
Inovise Medical, Inc., Beaverton, Oregon, USA.
Predicting atrial fibrillation (AF) recurrence after successful electrical cardioversion (ECV) is difficult. The main aim of this study was to investigate whether acoustic cardiography (AUDICOR® 200) immediately post-ECV might provide indices for AF relapse following cardioversion. Acoustic cardiography parameters included Electromechanical Activation Time (EMAT), Left Ventricular Systolic Time (LVST), QRS duration, heart rate and third heart sound intensity (S3 Strength).
View Article and Find Full Text PDFThe Immunology of CD1- and MR1-Restricted T Cells.
Annu Rev Immunol
May 2016
Department of Biomedicine, Basel University Hospital and Basel University, CH-4031 Basel, Switzerland; email: , ,
CD1- and MHC-related molecule-1 (MR1)-restricted T lymphocytes recognize nonpeptidic antigens, such as lipids and small metabolites, and account for a major fraction of circulating and tissue-resident T cells. They represent a readily activated, long-lasting population of effector cells and contribute to the early phases of immune response, orchestrating the function of other cells. This review addresses the main aspects of their immunological functions, including antigen and T cell receptor repertoires, mechanisms of nonpeptidic antigen presentation, and the current evidence for their participation in human and experimental diseases.
View Article and Find Full Text PDFOsteogenic graft vascularization and bone resorption by VEGF-expressing human mesenchymal progenitors.
Biomaterials
July 2013
Cell and Gene Therapy, Department of Biomedicine, Basel University Hospital and Basel University, Basel, Switzerland.
Article Synopsis
- Rapid vascularization of tissue-engineered osteogenic grafts is crucial for bone repair, and VEGF plays a key role in promoting vascular growth.
- A study using genetically modified human bone marrow-derived stromal/stem cells (BMSC) expressing rat VEGF showed a threefold increase in vascular density in grafts after 8 weeks in a rat model, with well-structured vascular networks.
- However, the excess VEGF led to a decrease in bone quantity and increased osteoclast recruitment, indicating a risk of disrupting bone balance, which complicates its use in clinical applications for bone tissue engineering.
Induction of aberrant vascular growth, but not of normal angiogenesis, by cell-based expression of different doses of human and mouse VEGF is species-dependent.
Hum Gene Ther Methods
February 2013
Cell and Gene Therapy, Department of Biomedicine and Department of Surgery, Basel University Hospital and Basel University, Basel CH-4031, Switzerland.
Therapeutic angiogenesis by vascular endothelial growth factor (VEGF) gene delivery is an attractive approach to treat ischemia. VEGF remains localized around each producing cell in vivo, and overexpression of mouse VEGF(164) (mVEGF(164)) induces normal or aberrant angiogenesis, depending strictly on its dose in the microenvironment in vivo. However, the dose-dependent effects of the clinically relevant factor, human VEGF(165) (hVEGF(165)), are unknown.
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