Olıgosarcoma: A Rare Case Report Wıth Dıstınct Features.

Oligosarcoma is a recently identified entity characterized by sarcomatous changes originating from oligodendroglioma. As of our current understanding, sarcomatous components are infrequent in glial tumors. The World Health Organization (WHO) classification describes sarcomatous features as a rare pattern in grade 3 oligodendrogliomas.

Mental health service utilization among patients followed up in tertiary HIV/AIDS clinics in Turkey: A need for integrated care.

Objectives: Mental health (MH) care for people living with HIV (PLWH) emerges as an important unmet need, yet there are no integrated HIV-MH clinics in Turkey. Our aim is to determine MH service use and its associated factors in PLWH followed up in the HIV/AIDS outpatient clinics in Istanbul/Turkey.

Methods: A cross-sectional study was conducted at the HIV/AIDS outpatient clinics of the Infectious Diseases (ID) departments in hospitals affiliated with the ACTHIV-IST Study Group.

Prognostic significance of actionable next-generation sequencing multigene panel in esophageal cancer treatment.

Objective: Next-generation sequencing (NGS) has been offered as a large-scale and effective genomic analyzing tool. In this research, we seek to examine the possible benefits of an actionable mutation panel in association with clinical and pathological features in the treatment of esophageal cancer.

Patients And Methods: In our study, 85 cases whose diagnosis of carcinoma was confirmed histopathologically either by endoscopic biopsy or esophageal surgery between 2010 and 2020 were identified from the hospital database.

Evaluation of histopathological findings in very old people (≥ 80 years old) in Turkish population.

Background: The lesions observed in very old populations exhibit a wide spectrum of characteristics. Histopathological evaluation may be necessary for accurate diagnosis in this demographic. There is limited amount of data on the histopathological evaluation of lesions in very old patients.

Anatomical insights into medial-sided talar dome osteochondral lesions: a comparative analysis of unilateral and bilateral cases and healthy controls using MRI measurements.

Background: The etiology of medial-sided talar osteochondral lesions (OCLs) remains insufficiently understood.

Purpose: To identify anatomical risk factors contributing to the development of unilateral or bilateral OCL of the talus on the medial side, utilizing morphological parameters derived from magnetic resonance imaging (MRI).

Material And Methods: In this retrospective study, 24 ankle MRI scans from 12 patients exhibiting bilateral OCLs of the talar dome on the medial side, 24 ankle MRIs from 24 patients with unilateral medial-sided OCLs, and 24 healthy controls matched for age, sex, and side within each group were analyzed.

Can smartphone cameras help with diagnostic adequacy in renal biopsy?

Background: In this prospective study, we evaluated whether a sufficient number of glomeruli were achieved using the 8× magnification of smartphone cameras.

Purpose: To increase the percutaneous ultrasound-guided renal biopsy (PURB) diagnostic value with a method that has not been tried before and reduce the need for repetition of the procedure.

Material And Methods: A total of 39 adult patients who underwent PURB were included in our study.

Optimizing analgesia for endometrial biopsy: A prospective, randomized comparative study.

Aim: This prospective, randomized, observational study aimed to compare the efficacy of intrauterine lidocaine, oral dexketoprofen, cervical lidocaine spray, and paracervical block with prilocaine for pain management during outpatient endometrial biopsy (EMB).

Methods: One hundred ninety-seven women aged 18-75 undergoing EMB were randomly assigned to one of four groups: intrauterine lidocaine (n = 49), oral dexketoprofen (n = 48), cervical lidocaine spray (n = 50), or paracervical block with prilocaine (n = 50). Pain intensity was assessed using a visual analog scale (VAS) immediately post-procedure and at 30 min, with additional analgesia needs recorded at 60 min.

Identifying predictors of persistent post-earthquake dizziness among adolescents after the 2023 earthquakes in Türkiye: A cross-sectional, multicenter study.

Objective: The impacts of earthquakes on the mental health of individuals have been well-documented. Additionally, individuals frequently report experiencing dizziness akin to seasickness or carsickness. This phenomenon, termed "post-earthquake dizziness syndrome" (PEDS), has garnered increasing attention due to its unclear etiology.

Single Mutation Different Clinical Findings: IGLL1 Defect.

Agammaglobulinemia is a rare inherited immunodeficiency disorder characterized by low or absent B cells with absent immunoglobulins. While X-linked agammaglobulinemia (XLA) is the most common type other genetic forms of agammaglobulinemia have been identified. During early childhood, passively transferred maternal Immunoglobulin G protects against various infections.

Clinical Presentation of Cat Scratch Disease in Pediatric Patients-A Single-Center Study.

Objective: Cat scratch disease (CSD) is the infectious disease caused by Bartonella henselae. Its typical presentation is regional lymphadenopathy. Also it may present with symptoms related to involved organs or disseminated disease with fever of unknown origin (FUO).

Improving speech intelligibility in noise and spatial perception: the critical role of hearing aid microphone position.

Introduction: Hearing aid (HA) manufacturers have introduced behind-the-ear (BTE) models where the microphone is positioned in the ear canal, which could impact auditory performance by distorting the pinna's acoustic cues. This study aimed to compare two different BTE HAs with varying microphone positions: the receiver in the ear (RITE) and the transducer in the ear (TIE).

Methods: The study involved 10 participants who had never used HAs before.

A descriptive analysis of 21 patients with pulmonary amyloidosis: An observational study.

Pulmonary amyloidosis is an extremely rare disease, often detected incidentally because of its asymptomatic nature and potential to result in fatal outcomes. In this study, we aimed to present the clinical and radiological features of patients diagnosed with pulmonary amyloidosis by biopsy. This descriptive study included 21 patients with pathologically diagnosed pulmonary amyloidosis.

Visual recovery following pituitary adenoma surgery: prognostic value of optical coherence tomography and suprasellar tumour volume.

Objective: The aim of this study is to investigate the effects of preoperative parameters such as retinal nerve fiber layer (RNFL) thickness, visual acuity (VA), visual field (VF), and tumour volume on postoperative outcomes in patients with pituitary adenoma.

Design: Retrospective study.

Participants: Two-hundred and seventy-six eyes from 142 patients were included.

The treatment efficacy of 7.5% dapsone gel in papulopustular rosacea: a prospective study.

Introduction: Topical dapsone has a level A recommendation for the treatment of papulopustular rosacea; however, its treatment efficacy has not been studied previously. The aim of this study is to evaluate the safety and efficacy of topical 7.5% dapsone gel applied once daily at night in the treatment of papulopustular rosacea.

Expanding the Genetic and Phenotypic Spectrum of Mowat-Wilson Syndrome: A Study of 10 Turkish Patients With an Intrafamilial Recurrence Caused by First Intragenic Large Deletion.

Mowat-Wilson syndrome (MWS) is a complex disorder caused by heterozygous ZEB2 gene variations creating haploinsufficiency. The main clinical features are evolving facial dysmorphism, intellectual disability, eye and brain malformations, and various organ anomalies. Our study examines 10 Turkish patients, who had clinical diagnosis, underwent evaluation, clinical investigations, and genetic tests in multiple tertiary centers across Türkiye, and were molecularly diagnosed with MWS.

Integrating PET/CT, radiomics and clinical data: An advanced multi-modal approach for lymph node metastasis prediction in prostate cancer.

The involvement of lymph nodes critically affects patient outcomes in prostate cancer. While traditional risk models use factors like stage and PSA levels, the detection of lymph node involvement through modalities like PET targeting PSMA with Ga radiotracer plays a pivotal role in guiding treatments ranging from prostatectomy to pelvic radiotherapy. This study aims to create a deep learning model to predict lymph node involvement in intermediate to high-risk prostate cancer patients using Ga-PSMA PET/CT imagery, radiomics features, and various clinical parameters.

Safety and feasibility of robotic surgery in geriatric patients with rectal cancer.

Background: The incidence of rectal cancer is increasing in the elderly population, yet the safety of surgical interventions in this group, particularly robotic surgery, is still debated. This study aims to investigate the safety and short-term postoperative outcomes of robotic surgery in geriatric patients (aged ≥ 70 years) with rectal cancer.

Patients: Patients diagnosed with rectal cancer and undergoing robotic surgery between March 2021 and September 2023 were divided into two groups based on age: the elderly group (aged ≥ 70 years) and the younger group (aged < 70 years), totaling 108 patients.

Sural-to-medial femoral cutaneous amplitude ratio in early diagnosis of uremic neuropathy.

Introduction: Medial femoral cutaneous (MFC) sensory nerve action potentials (SNAPs) can be easily recorded using distal stimulation. This study aimed to identify a new parameter using MFC SNAPs for the early electrophysiological diagnosis of length-dependent axonal polyneuropathy (LDAP) associated with uremic neuropathy.

Methods: Patients with chronic renal failure who were referred to the electrodiagnostic laboratory due to symptoms suggesting polyneuropathy were included.

Impact of uterine cavity filling pressure levels on pain and procedure duration in diagnostic hysteroscopy: A retrospective cohort study.

Aim: This study investigates the impact of intracavitary pressure levels on pain, visualization quality, and procedure duration in office hysteroscopy, comparing standard pressures (60-100 mmHg) with high pressures (110-150 mmHg).

Methods: We conducted a retrospective cohort study involving non-menopausal women undergoing diagnostic hysteroscopy at a tertiary clinic. Patients were categorized into two groups based on intracavitary pressure: the standard pressure group (60-100 mmHg; n = 72) and the high-pressure group (110-150 mmHg; n = 37).