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The effect of nano-hydroxyapatite on white spot lesions: A systematic review and meta-analysis.

J Dent

December 2024

Cariology in Relation to Minimally Invasive Dentistry/Oral Bioengineering, Institute of Dentistry, Queen Mary University of London, Barts and the Royal London Dental Hospital, Turner Street, London, E1 2AD, UK. Electronic address:

Objectives: To assess the effect of nano-hydroxyapatite (nano-HAP) either with or without fluoride on white spot lesions (WSLs) in terms of remineralisation and colour change.

Data Sources: An electronic search was carried out in MEDLINE via PubMed, Scopus, Web of Science, LILACS, Embase, Cochrane Library, Google Scholar, Grey literature, and hand search. There were no limitations in terms of language and date (till August 2024) and all studies meeting the inclusion criteria were included.

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