Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation with Pre Induction IV Fentanyl Versus Combination of IV Fentanyl and Sub Lingual Nitroglycerin Spray.

Introduction: Endotracheal intubation is one of the most invasive stimuli in anesthesia and it's often accompanied by a hemodynamic pressor response. The purpose of this study was to investigate the efficacy of a single pre-induction 2 µg/kg bolus injection of fentanyl followed by two puffs of nitroglycerin sub lingual spray (400 µg /spray) with a thiopentone/suxamethonium sequence in the attenuation of the hemodynamic response to endotracheal intubation in normotensive patients.

Material And Methods: The study consisted of 80 randomly selected ASA physical status I/II male/female adults who were aged between 18 through 60 years and scheduled for elective surgery.

The cicadas of Argentina with new records, a new genus and fifteen new species (Hemiptera: Cicadoidea: Cicadidae).

The Argentine cicada fauna is determined. A total of 108 species belonging to 37 genera, eight tribes, and three subfamilies of cicadas are represented in the Argentine cicada fauna. One genus and 15 species are described as new to science: Torresia Sanborn & Heath gen.

Is patient confidentiality compromised with the electronic health record?: a position paper.

In order for electronic health records to fulfill their expected benefits, protection of privacy of patient information is key. Lack of trust in confidentiality can lead to reluctance in disclosing all relevant information, which could have grave consequences. This position paper contemplates whether patient confidentiality is compromised by electronic health records.

Breast Self-examination and Health Beliefs in Grenadian Women.

Background: Breast cancer incidence and mortality are rising in Grenada, and there is a lack of knowledge about women's beliefs about breast self-examination (BSE).

Objective: The objective of this study was to quantify and identify patterns of beliefs about health and BSE in Grenadian women to help plan targeted community interventions.

Methods: In this descriptive cross-sectional study of 110 women in a community parish in Grenada, sociodemographic data and health beliefs were collected using a self-administered questionnaire.

The use of human amnion/chorion membrane in the clinical setting for lower extremity repair: a review.

Unsuccessful healing represents a significant medical dilemma for both patients and clinicians and create a financial burden on the health care system. Despite the efforts of physicians, many injuries fail to heal with standard care alone. For decades human amniotic membrane composed of both amnion and chorion has shown remarkable therapeutic potential, but only recent preservation methods have allowed its widespread use.

Revisiting the bound on axion-photon coupling from globular clusters.

We derive a strong bound on the axion-photon coupling g(aγ) from the analysis of a sample of 39 Galactic Globular Clusters. As recognized long ago, the R parameter, i.e.

The two-step mechanochemical synthesis of porphyrins.

Porphyrin synthesis under solvent-free conditions represents the "greening" of a traditional synthesis that normally requires large amounts of organic solvent, and has hindered the industrial-scale synthesis of this useful class of molecules. We have found that the four-fold acid-catalysed condensation of aldehyde and pyrrole to yield a tetra-substituted porphyrin is possible through mechanochemical techniques, without a solvent present. This represents one of the still-rare examples of carbon-carbon bond formation by mechanochemistry.

Genomics Analysis of Replicative Helicase DnaB Sequences in Proteobacteria.

Replicative Helicase DnaB interacts with DnaA, DnaC, DnaG, and DNA polymerase III to commence replication, increase the movement rate of the replication fork, and to assemble part of the primosome. The formation of the replication fork is limited by the ability to load DnaB to the DNA, thus DnaB has shown to be vital to a large extent. In the absence of DnaB, the replication fork is not maintained and in a state of inactivity the replication fork degrades and collapses.

Train the Brain: Novel Electroencephalography Data Indicate Links between Motor Learning and Brain Adaptations.

EEG differences were examined between part and whole practice in the learning of a novel motor task. Recording was done at 4 sites (i.e.

Adverse childhood experiences in the lives of female sex offenders.

This study explored the prevalence of early trauma in a sample of U.S. female sexual offenders (N = 47) using the Adverse Childhood Experiences (ACE) scale.

Retinal ganglion cell polarization using immobilized guidance cues on a tissue-engineered scaffold.

Cell transplantation therapies to treat diseases related to dysfunction of retinal ganglion cells (RGCs) are limited in part by an inability to navigate to the optic nerve head within the retina. During development, RGCs are guided by a series of neurotrophic factors and guidance cues; however, these factors and their receptors on the RGCs are developmentally regulated and often not expressed during adulthood. Netrin-1 is a guidance factor capable of guiding RGCs in culture and relevant to guiding RGC axons toward the optic nerve head in vivo.

Variation in BAS-BIS profiles across categories of cigarette use.

Cigarette smoking is a major health concern, especially among college students. Research suggests a number of individual difference variables may be useful for identifying people at risk of becoming smokers and their likelihood of successfully quitting. The current study focuses on individual differences relating to Behavioral Inhibition System sensitivity (BIS) and the fun seeking, reward responsiveness, and drive aspects of Behavioral Approach System sensitivity (BAS).

Evaluation of ActiGraph's low-frequency filter in laboratory and free-living environments.

Unlabelled: The ActiGraph (AG) is the most commonly used research-grade physical activity monitor. Although several investigators have examined the effects of the "low-frequency extension" (LFE) on step counts in the free-living environment, a direct comparison with a valid criterion method is lacking. We sought to determine the accuracy of the AG's LFE to measure step counts during laboratory and free-living activities in two versions of the device (GT1M and GT3X).

Treatment of suspected acute perforated appendicitis with antibiotics and interval appendectomy.

Background: Initial antibiotics with planned interval appendectomy (interval AP) have been used to treat patients with complicated perforated appendicitis; however, little experience exists with this approach in children with suspected acute perforated appendicitis (SAPA). We sought to determine the outcome of initial antibiotics and interval AP in children with SAPA.

Methods: Over an 18-month period, 751 consecutive patients underwent appendectomy including 105 patients with SAPA who were treated with initial intravenous antibiotics and planned interval AP ≥ 8 weeks after presentation.

Role of cell cycle regulatory molecules in retinoic acid- and vitamin D3-induced differentiation of acute myeloid leukaemia cells.

The important role of cell cycle regulatory molecules in all trans-retinoic acid (ATRA)- and vitamin D3-induced growth inhibition and differentiation induction has been intensively studied in both acute myeloid leukaemia primary cells and a variety of leukaemia cell lines. Cyclin-dependent kinases (CDK)-activating kinase has been demonstrated to interact with retinoic acid receptor (RAR)α in acute promyelocytic leukaemia cells, and inhibition of CDK-activating kinase by ATRA causes hypophosphorylation of PML-RARα, leading to myeloid differentiation. In many cases, downregulation of CDK activity by ATRA and vitamin D3 is a result of elevated p21- and p27-bound CDKs.

MESAFace, a graphical interface to analyze the MESA output.

Unlabelled: MESA (Modules for Experiments in Stellar Astrophysics) has become very popular among astrophysicists as a powerful and reliable code to simulate stellar evolution. Analyzing the output data thoroughly may, however, present some challenges and be rather time-consuming. Here we describe MESAFace, a graphical and dynamical interface which provides an intuitive, efficient and quick way to analyze the MESA output.

Competition and the impact of online hospital report cards.

Information on the quality of healthcare gives providers an incentive to improve care, and this incentive should be stronger in more competitive markets. We examine this hypothesis by studying Pennsylvanian hospitals during the years 1995-2004 to see whether those hospitals located in more competitive markets increased the quality of the care provided to Medicare patients after report cards rating the quality of their Coronary Artery Bypass Graft programs went online in 1998. We find that after the report cards went online, hospitals in more competitive markets used more resources per patient, and achieved lower mortality among more severely ill patients.

For love or money: registered nurses who return to hospital practice.

Aim: This commentary explores the value that returning nurses bring to the hospital setting.

Background: Nurses who have left hospital practice, usually due to family obligations, often return once the children are older. They return because they love nursing or they need to make money.

A Rare Case of Aggressive Digital Adenocarcinoma of the Lower Extremity, Masquerading as an Ulcerative Lesion that Clinically Favored Benignancy.

A rare case report of Aggressive Digital Adenocarcinoma (ADPCa) is presented complete with a literature review encompassing lesions that pose potential diagnostic challenges. Similarities between basal cell carcinoma (BCC), marjolin's ulceration/squamous cell carcinoma (MSCC) and ADPCa are discussed. This article discusses potential treatment options for ADPCa and the need for early biopsy when faced with any challenging lesion.

Human acellular dermal wound matrix: evidence and experience.

A chronic wound fails to complete an orderly and timely reparative process and places patients at increased risk for wound complications that negatively impact quality of life and require greater health care expenditure. The role of extracellular matrix (ECM) is critical in normal and chronic wound repair. Not only is ECM the largest component of the dermal skin layer, but also ECM proteins provide structure and cell signalling that are necessary for successful tissue repair.

Effects of language of assessment on the measurement of acculturation: measurement equivalence and cultural frame switching.

The present study used a randomized design, with fully bilingual Hispanic participants from the Miami area, to investigate 2 sets of research questions. First, we sought to ascertain the extent to which measures of acculturation (Hispanic and U.S.

Perceived context of reception among recent Hispanic immigrants: conceptualization, instrument development, and preliminary validation.

Context of reception has been discussed widely in the sociological and anthropological literature, but no measures of this construct exist. We designed a measure of perceived context of reception and provide initial support for the factorial validity, internal consistency reliability, and incremental and discriminant validity of scores generated by this measure. A sample of 302 recent-immigrant Hispanic parent-adolescent dyads from Miami and Los Angeles completed the new perceived context of reception measure, as well as measures of perceived discrimination; Hispanic/American cultural practices, values, and identifications; and depressive symptoms.

Finding the best antibody dilution by repeated immunostaining of the same tissue section.

One can find the optimal antibody dilution for immunostaining by repeated staining on the same tissue section by using a less dilute antibody for each attempt. Using secondary antibody and horseradish peroxidase conjugated to a dextran polymer, a section stained repeatedly with several dilutions of antibody appears as good as a section stained with only the last dilution.

Fundaments of optical far-field subwavelength resolution based on illumination with surface waves.

We present a general discussion about the fundamental physical principles involved in a novel class of optical superlenses that permit to realize in the far-field direct non-scanning images with subwavelength resolution. Described superlenses are based in the illumination of the object under observation with surface waves excited by fluorescence, the enhanced transmission of fluorescence via coupling with surface waves, and the occurrence of far-field coherence-related fluorescence diffraction phenomena. A Fourier optics description of the image formation based on illumination with surface waves is presented, and several recent experimental realizations of this technique are discussed.

Variations of the origin of the arcuate artery.

Background: The purpose of this study was to investigate the origin of the arcuate artery.

Methods: This cadaveric study was performed on 20 feet from ten cadavers of both sexes (age range, 61-94 years).

Results: The results indicate that the arcuate artery originated from the dorsalis pedis artery in 13 of 20 specimens (65%) and from the lateral tarsal artery in 6 of 20 (30%), and a variation in origination was noted in 1 of 20 specimens (5%).