Social support buffering of the relation between low income and elevated blood pressure in at-risk African-American adults.

Socioeconomic disadvantage has been linked to elevated blood pressure (BP), and the purpose of this study was to assess whether interpersonal social supports buffer these adverse relations in African-American adults. In three communities matched demographically, a subsample of participants (N = 204) of the Positive Action for Today's Health trial provided measures of perceived social support, annual household income, and BP. Multiple regression analyses with cross-product interactions were conducted using follow-up data.

Misuse of stimulant medication among college students: a comprehensive review and meta-analysis.

The misuse of stimulant medication among college students is a prevalent and growing problem. The purpose of this review and meta-analysis is to summarize the current research on rates and demographic and psychosocial correlates of stimulant medication misuse among college students, to provide methodological guidance and other ideas for future research, and to provide some preliminary suggestions for preventing and reducing misuse on college campuses. Random-effects meta-analysis found that the rate of stimulant medication misuse among college students was estimated at 17 % (95 % CI [0.

Disruptive Behavior Disorders and Marijuana Use: The Role of Depressive Symptoms.

Objective: The present study sought to examine the relations among disruptive behavior disorders (DBDs; ie, attention-deficit/hyperactivity disorder [ADHD], conduct disorder [CD], oppositional defiant disorder [ODD]), depressive symptoms, and marijuana use among a sample of late adolescents and emerging adults.

Method: A total of 900 students (75.8% female, 80.

Is implementation fidelity associated with improved access to care in a school-based Child and Family Team model?

Effective child and family centered service planning is crucial to addressing vulnerable children's needs. However, there is limited evidence about what facets of these processes improve service use and outcomes. The current study used a Poisson random effects hazard model to test correlations between fidelity to NC's Child and Family Support Team model and time to service receipt, using case management data for 3396 children served by that program during the 2008-2009 school year.

Reading and phonological skills in boys with fragile X syndrome.

Although reading skills are critical for the success of individuals with intellectual disabilities, literacy has received little attention in fragile X syndrome (FXS). This study examined the literacy profile of FXS. Boys with FXS (n = 51; mean age 10.

Context-dependent pathways of the transmission of risk from communities to individuals.

Research has consistently documented the role of environmental risk factors in the onset of delinquent behavior among youth. Less is known about the processes through which these contextual risks are translated to individual youth behavior. The aim of the current study is to examine the role of family risk factors in the transmission of community risk.

Neuronal injury in the motor cortex after chronic stroke and lower limb motor impairment: a voxel-based lesion symptom mapping study.

Many studies have examined motor impairments using voxel-based lesion symptom mapping, but few are reported regarding the corresponding relationship between cerebral cortex injury and lower limb motor impairment analyzed using this technique. This study correlated neuronal injury in the cerebral cortex of 16 patients with chronic stroke based on a voxel-based lesion symptom mapping analysis. Neuronal injury in the corona radiata, caudate nucleus and putamen of patients with chronic stroke could predict walking speed.

Does distress intolerance moderate the link between ADHD symptoms and number of sexual partners?

Previous research demonstrates that ADHD symptoms are related to increased risky sexual behavior. Distress intolerance (DIT) has also been linked to risk behavior and may also be related to increased risky sexual behavior. Thus, we evaluated the degree to which DIT moderated the link between ADHD symptoms and number of casual and monogamous sexual partners.

Predicting high-risk versus -risk substance use during late adolescence from early adolescent risk factors using Latent Class Analysis.

Much of the existing risk factor literature focuses on identifying predictors of low-levels of substance use versus higher-levels of substance use. In this paper, we explore more nuanced patterns of alcohol, tobacco, and other drug (ATOD) use during late adolescence. Our aims were to: 1) identify subgroups of youth with qualitatively different patterns of ATOD use; and 2) explore whether membership among qualitatively distinct, high-risk classes could be predicted based on early adolescent risk factors.

A longitudinal study of the effects of instrumental and emotional social support on physical activity in underserved adolescents in the ACT trial.

Background: Few previous studies have examined the influence of instrumental and emotional social support on physical activity (PA) longitudinally in underserved adolescents.

Purpose: This longitudinal study was a secondary analysis of the Active by Choice Today (ACT) trial examining whether instrumental social support predicts increases in PA in underserved adolescents, above and beyond emotional social support provided by family or peers.

Methods: Students in the sixth grade (N = 1,422, 73 % African American, 54 % female, M age = 11 years) in the ACT trial participated.

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

HIV-1 enters the central nervous system early in infection; although HIV-1 does not directly infect neurons, HIV-1 may cause a variety of neurological disorders. Neuronal loss has been found in HIV-1, but synaptodendritic injury is more closely associated with the neurocognitive disorders of HIV-1. The HIV-1 transactivator of transcription (Tat) protein causes direct and indirect damage to neurons.

Project SHINE: effects of parent-adolescent communication on sedentary behavior in African American adolescents.

Objective: This study examined parenting variables (communication, monitoring) as moderators of a family-based intervention for reducing sedentary behavior (SB) in African American adolescents. As a secondary aim, a similar model was tested using adolescent weight status as the outcome.

Methods: African American adolescents (n = 73; 12.

Associations among environmental supports, physical activity, and blood pressure in African-American adults in the PATH trial.

High blood pressure disproportionately affects African-American adults and is a leading cause of stroke and heart attack. Engaging in recommended levels of physical activity reduces blood pressure, and social and physical environmental supports for physical activity may increase engagement in physical activity. Based on social cognitive theory within a bioecological framework, the present study tested hypotheses that perceived peer social support for physical activity and neighborhood walkability would be positively associated with physical activity, and that physical activity would mediate their relation with blood pressure.

The Carrot and the Stick: A Cross-Sectional Study of the Influences on Responsible Merchant Practices to Reduce Underage Drinking.

Alcohol merchants (N=331) completed a cross-sectional survey assessing their attitudes and beliefs about underage drinking, its likely consequences, requirements for responsible beverage service (RBS) training, and performance of RBS practices and checking IDs. Merchants requiring more rigorous RBS training (i.e.

Partner discrepancies in distressed marriages.

Spousal discrepancy theory posits that partners with wide personality differences are at risk for marital distress. In this study, we assessed links between partner personality and interpersonal characteristics and marital distress in 244 couples who sought marital therapy. The sample was divided into three subgroups according to marital duration.

Imputational modeling of spatial context and social environmental predictors of walking in an underserved community: the PATH trial.

Background: This study examined imputational modeling effects of spatial proximity and social factors of walking in African American adults.

Purpose: Models were compared that examined relationships between household proximity to a walking trail and social factors in determining walking status.

Methods: Participants (N=133; 66% female; mean age=55 years) were recruited to a police-supported walking and social marketing intervention.

Predictors of Academic Achievement for School Age Children with Sickle Cell Disease.

Background: Children with sickle cell disease (SCD) are at risk for neurocognitive impairment and poor academic achievement, although there is limited research on factors predicting academic achievement in this population. This study explores the relative contribution to academic achievement of a comprehensive set of factors, such as environmental (socioeconomic status), disease-related (stroke, transfusion therapy, adherence), and psychosocial variables (child behavior, child quality of life (QoL)), controlling for intellectual functioning (IQ).

Methods: Eighty-two children with SCD completed measures assessing IQ and academic achievement, while parents completed questionnaires assessing adherence, child behavior, and child quality of life.

Weight status as a moderator of the relationship between motivation, emotional social support, and physical activity in underserved adolescents.

Objective: This study examined weight status as a moderator of the relationship between motivation (controlled, autonomous, regulatory), emotional social support (parents, peers) and moderate-to-vigorous physical activity (MVPA) in underserved adolescents (ethnic minority, low-income).

Methods: Participants from the Active by Choice Today Trial (n = 1,416; 54% girls, 73% African American, 52% overweight/obese) completed baseline measures, including height and weight, psychosocial surveys, and 7-day accelerometry estimates. Weight status was defined by body mass index z-score (zBMI).

Effects of parenting style and parent-related weight and diet on adolescent weight status.

Objective: This study examined the interaction between parental limit setting of sedentary behaviors and health factors (weight status, physical activity [PA], fruit and vegetable [FV] intake) on standardized body mass index (zBMI) in African American adolescents.

Methods: Data were from 67 parent-adolescent dyads. Parental limit setting, PA and FV intake were assessed via self-report, and objective height and weight measurements were collected.

Do ADHD symptoms moderate the relation between positive alcohol expectancies and alcohol-related outcomes?

Research indicates that attention-deficit/hyperactivity disorder (ADHD) may be a risk factor for heavy alcohol use and related problems. Research also suggests that positive alcohol expectancies (i.e.

A longitudinal assessment of the associations among response access, attention problems, and aggression during childhood.

Children with ADHD symptoms often display social competence deficits, yet mechanisms for their social difficulties remain unclear. Using data from the normative sample of non-intervention respondents (N = 387; 50 % male; 49 % non-European-American; age at initial assessment: M = 6.5 years, SD = 0.

Neural correlates of race-related social evaluations for African Americans and white Americans.

Objective: To examine differences in patterns of brain activation associated with a race-related social evaluative task for a sample of African American and White American adults.

Method: Participants were exposed to images of White American and African American targets embedded in various contexts across three emotional valences: angry/hostile, happy/joyful, and neutral/ambiguous. Functional magnetic resonance imaging was used to measure brain activity.

Formative process evaluation for implementing a social marketing intervention to increase walking among African Americans in the Positive Action for Today's Health trial.

Objectives: Evaluating programs targeting physical activity may help to reduce disparate rates of obesity among African Americans. We report formative process evaluation methods and implementation dose, fidelity, and reach in the Positive Action for Today's Health trial.

Methods: We applied evaluation methods based on an ecological framework in 2 community-based police-patrolled walking programs targeting access and safety in underserved African American communities.

Accelerometry cut points for physical activity in underserved African Americans.

Background: Despite their increased use, no studies have examined the validity of Actical accelerometry cut points for moderate physical activity (PA) in underserved (low-income, high-crime), minority populations. The high rates of chronic disease and physical inactivity in these populations likely impact the measurement of PA. There is growing concern that traditionally defined cut points may be too high for older or inactive adults.

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

The interactive effects of HIV-1 infection and methamphetamine (METH) abuse in producing cognitive dysfunction represent a serious medical problem; however, the neural mechanisms underlying this interactive neurotoxicity remain elusive. In this study, we report that a combination of low, sub-toxic doses of METH + HIV-1 Tat 1-86 B, but not METH + HIV-1 gp120, directly induces death of rodent midbrain neurons in vitro. The effects of D1- and NMDA-receptor specific antagonists (SCH23390 and MK-801, respectively) on the neurotoxicity of different doses of METH or HIV-1 Tat alone and on the METH + HIV-1Tat interaction in midbrain neuronal cultures suggest that the induction of the cell death cascade by METH and Tat requires both dopaminergic (D1) and N-methyl D-aspartate (NMDA) receptor-mediated signaling.